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Q0W6L7 (SYR_UNCMA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:UNCMA_22090
ORF Names:RCIX568
OrganismUncultured methanogenic archaeon RC-I [Complete proteome] [HAMAP]
Taxonomic identifier351160 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanocellalesMethanocellaceaeMethanocella

Protein attributes

Sequence length563 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 563563Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018142

Regions

Motif119 – 12911"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q0W6L7 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: B6BE5762112717D7

FASTA56363,244
        10         20         30         40         50         60 
MYLKLLEEAG RLMKQAVADA GYTVEDMSLV ESQHADVSSS LPFRLAKELK KNPKEIAAAI 

        70         80         90        100        110        120 
VEKMGKSEYI DRVEATGAYI NFYASQKYIT DSLKEILSEK KFFELEPNGI KVILEHTSAN 

       130        140        150        160        170        180 
PTGPLHVGRG RNPIIGDTLA RLLRAGGYDL EVQYYVDDMG KQEATIVWGY DHLDRIKPGK 

       190        200        210        220        230        240 
PDTDKPDHEI VEVYRAATDL RKSDEAVEKE ISEILNAYEH MDPATAVKFR EMVERCLEGQ 

       250        260        270        280        290        300 
KMTLARMNVF YDRFVWESDF VRDGSVNKAV KKLAESQYAT TKDGALALDL SSFGMDKEFV 

       310        320        330        340        350        360 
LTRADGTSLY TTRDIAFHVW KLARCDRAIN VLGEDQKLAM QRLNAALSIL GEKKAPTIVF 

       370        380        390        400        410        420 
YSFVSLPEGR MSTRKGVVVN LDDLLDEAVE RAYVEVDKRR KDIPEEKKRQ IAEAVGIGAV 

       430        440        450        460        470        480 
RFDIVRVAPE KSITFKWETA LDFEKQGAPF IQYAHARCCS ILEKAKPGEY DASMLREPEE 

       490        500        510        520        530        540 
AALVKKIAMM PYVIKNASTE LKPHVIAIYA RELAEAFNQF YRVSPVLIAE PELKEARLAL 

       550        560 
VEASRKALAA SLGMLGIAAI EEM 

« Hide

References

[1]"Genome of rice cluster I archaea -- the key methane producers in the rice rhizosphere."
Erkel C., Kube M., Reinhardt R., Liesack W.
Science 313:370-372(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM114193 Genomic DNA. Translation: CAJ35976.1.
RefSeqYP_685302.1. NC_009464.1.

3D structure databases

ProteinModelPortalQ0W6L7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING351160.RCIX568.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAJ35976; CAJ35976; RCIX568.
GeneID5144438.
KEGGrci:RCIX568.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247213.
KOK01887.
OMANPNGPLH.
ProtClustDBCLSK2789673.

Enzyme and pathway databases

BioCycUMET351160:GJT4-2269-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR_UNCMA
AccessionPrimary (citable) accession number: Q0W6L7
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 5, 2006
Last modified: April 16, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries