Q0W628 (TRPF_UNCMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	UNCMA_20230
ORF Names:	RCIX795

Organism

Uncultured methanogenic archaeon RC-I [Complete proteome] [HAMAP]

Taxonomic identifier

351160 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Methanomicrobia › Methanocellales › Methanocellaceae › Methanocella › Methanocella arvoryzae

Protein attributes

Sequence length	213 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 213	213	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135		PRO_1000018647

Sequences

	Sequence		Length	Mass (Da)
	Q0W628 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: E35D1BD9081733F2	FASTA	213	22,774
	10 20 30 40 50 60 MTRVKICGTT TPEDALACAV SGADAIGMLV DVRISPRCIT ADQARLITSV LPPFVASVIV 70 80 90 100 110 120 MQPSTPGEVV DAVRKIRPTA VQLHGSEPPD FLKHIKLQVP GVRLIKTIHV GEGGEIEKAR 130 140 150 160 170 180 QYEGVADAIL LDTASARGGG MGITHDWNVS REIIGSVRLP VILAGGLSPK NVAEAIEAAR 190 200 210 PYAVDVCSGV EAEKRKKDLR LVREFIEQVR VTK

References

[1]	"Genome of rice cluster I archaea -- the key methane producers in the rice rhizosphere." Erkel C., Kube M., Reinhardt R., Liesack W. Science 313:370-372(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM114193 Genomic DNA. Translation: CAJ36165.1.
RefSeq	YP_685491.1. NC_009464.1.
3D structure databases
ProteinModelPortal	Q0W628.
ModBase	Search...
Protein-protein interaction databases
STRING	351160.RCIX795.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAJ36165; CAJ36165; RCIX795.
GeneID	5145424.
KEGG	rci:RCIX795.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0135.
HOGENOM	HOG000161598.
KO	K01817.
OMA	RISPRCI.
ProtClustDB	CLSK2789600.
Enzyme and pathway databases
BioCyc	UMET351160:GJT4-2076-MONOMER.
UniPathway	UPA00035; UER00042.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00135. PRAI.
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI_dom. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_UNCMA

Accession

Primary (citable) accession number: Q0W628

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 5, 2006
Last modified:	May 29, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program