Reviewed, UniProtKB/Swiss-Prot Q0W1C7 (PDAD_UNCMA)

Names and origin

Protein names

Recommended name:
    Pyruvoyl-dependent arginine decarboxylase
      Short name=PvlArgDC
    EC=4.1.1.19
Cleaved into the following 2 chains:
    1- Recommended name:
            Pyruvoyl-dependent arginine decarboxylase subunit beta
    2- Recommended name:
            Pyruvoyl-dependent arginine decarboxylase subunit alpha

Gene names

Name:	pdaD
Ordered Locus Names:	UNCMA_04430
ORF Names:	RRC25

Organism

Uncultured methanogenic archaeon RC-I [Complete proteome] [HAMAP]

Taxonomic identifier

351160 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › environmental samples

Protein attributes

Sequence length	166 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	L-arginine = agmatine + CO2. HAMAP MF_01404
Cofactor	Pyruvoyl group By similarity. HAMAP MF_01404
Sequence similarities	Belongs to the pdaD family.

Ontologies

Keywords
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	arginine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 44	44	Pyruvoyl-dependent arginine decarboxylase subunit beta By similarity		PRO_1000068403
	Chain	45 – 166	122	Pyruvoyl-dependent arginine decarboxylase subunit alpha By similarity		PRO_1000068404
Sites
	Site	44 – 45	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	45	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0W1C7-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: A971F8C24DB7D886	FASTA	166	18,471
	10 20 30 40 50 60 MRQGLVPKKV FFTSGVGRHR EMLESFEMAL RDAGIEKFNL VTVSSILPPD CEIVQKSEGL 70 80 90 100 110 120 PSLYPGEIVF TVMSRNSSNE PSRRIAASIG CAIPKDPVKN FGYLSEHHSY GETEQYAGMY 130 140 150 160 AEKLAENMLF TWTKEKPGKT MNISKTAEVD DEGNWTTVIS AAVFIL

References

[1]	"Genome of rice cluster I archaea -- the key methane producers in the rice rhizosphere." Erkel C., Kube M., Reinhardt R., Liesack W. Science 313:370-372(2006) [PubMed: 16857943] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM114193 Genomic DNA. Translation: CAJ37816.1.
RefSeq	YP_687142.1.
3D structure databases
SMR	Q0W1C7. Positions 5-44.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0W1C7.
Genome annotation databases
GeneID	5143395.
GenomeReviews	Gene locus UNCMA_04430 in contig AM114193_GR.
KEGG	rci:RRC25.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG07911.
HOGENOM	HBG539680.
OMA	ISEYHAY.
Family and domain databases
HAMAP	MF_01404. PvlArgDC. [Tree]
InterPro	IPR016104. Pyr-dep_his/arg-deCO2ase. IPR016105. Pyr-dep_his/arg-deCO2ase_sand. IPR002724. Pyruvoyl-dep_arg_deCO2ase. [Graphical view]
Gene3D	G3DSA:3.50.20.10. Pyr-dep_his/arg-deCO2ase_sand. 1 hit.
Pfam	PF01862. PvlArgDC. 1 hit. [Graphical view]
PIRSF	PIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDom	PD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00286. PvlArgDC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PDAD_UNCMA

Accession

Primary (citable) accession number: Q0W1C7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	September 5, 2006
Last modified:	February 9, 2010
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)