Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q0W0X1

- DNLI_UNCMA

UniProt

Q0W0X1 - DNLI_UNCMA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

DNA ligase

Gene

lig

Organism
Uncultured methanogenic archaeon RC-I
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.UniRule annotation

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

Cofactori

a divalent metal cationUniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei249 – 2491ATPUniRule annotation
Active sitei251 – 2511N6-AMP-lysine intermediateUniRule annotation
Binding sitei256 – 2561ATPUniRule annotation
Binding sitei271 – 2711ATPUniRule annotation
Binding sitei301 – 3011ATPUniRule annotation
Binding sitei342 – 3421ATPUniRule annotation
Binding sitei418 – 4181ATPUniRule annotation
Binding sitei424 – 4241ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-HAMAP
  4. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
  3. DNA biosynthetic process Source: InterPro
  4. DNA recombination Source: UniProtKB-HAMAP
  5. DNA repair Source: UniProtKB-HAMAP
  6. DNA replication Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication

Keywords - Ligandi

ATP-binding, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciUMET351160:GJT4-304-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP]UniRule annotation
Gene namesi
Name:ligUniRule annotation
Ordered Locus Names:UNCMA_02940
ORF Names:RRC227
OrganismiUncultured methanogenic archaeon RC-I
Taxonomic identifieri351160 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanocellalesMethanocellaceaeMethanocella
ProteomesiUP000000663: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 568568DNA ligasePRO_0000365268Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi351160.RRC227.

Structurei

3D structure databases

ProteinModelPortaliQ0W0X1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000036008.
KOiK10747.
OMAiVPIVIPY.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPiMF_00407. DNA_ligase.
InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0W0X1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLFKELVSLY ESLRSTSSRL EKTAMIAAFL QQAPVDELPV IVTFLTGRIF
60 70 80 90 100
PEWDQRKIGI ASQSMIKIIS TITHNPEDAV VESYKKTGHL GVTAEEMFQK
110 120 130 140 150
RRQVTFFEPE DITVKEVAET FYEIARSSGA GSSAKKQKIL IGLLHRATTP
160 170 180 190 200
KEAHYIVSLT IEYVLSGAKE GVMEDAIGQA FGATLDQVRR AHMLTSDLGE
210 220 230 240 250
TARIAKTEGA AGLEAITIRP MRPVRPMLAQ NVSSIREALD TMGGVAEFEM
260 270 280 290 300
KYDGARLQIH KVGKDVKLYS RRLEDLTDAL PEIVGYVRES VKSDTAILDS
310 320 330 340 350
ECIAIDKDTG RPIPFQNILT RLRRIHKVEE TQKQFPLILR PFDVLFNQGQ
360 370 380 390 400
STIDLPLRER RKILEEIVIA TDSVIQPARA LVTDQEEKAQ ELFEESVKSG
410 420 430 440 450
NEGLMGKDLN ATYTPGVRGK KMVKIKSVLD TLDLAIVSAE WGHGRKAGWL
460 470 480 490 500
TSFEVAALDE ETGDYVILGR VASGFSDEQL IEMTEKLKPL ITGEHGRIVD
510 520 530 540 550
VRPEIIVEVK FEEIQKSPIY SSGYALRFPR LVRVRDDLSP EEVNSFTRVM
560
NIYNVQQRYS ISENGLRK
Length:568
Mass (Da):63,701
Last modified:September 5, 2006 - v1
Checksum:iC2F4F34F06A1FB48
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM114193 Genomic DNA. Translation: CAJ37972.1.
RefSeqiYP_687298.1. NC_009464.1.

Genome annotation databases

EnsemblBacteriaiCAJ37972; CAJ37972; RRC227.
GeneIDi5143728.
KEGGirci:RRC227.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM114193 Genomic DNA. Translation: CAJ37972.1 .
RefSeqi YP_687298.1. NC_009464.1.

3D structure databases

ProteinModelPortali Q0W0X1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 351160.RRC227.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ37972 ; CAJ37972 ; RRC227 .
GeneIDi 5143728.
KEGGi rci:RRC227.

Phylogenomic databases

eggNOGi COG1793.
HOGENOMi HOG000036008.
KOi K10747.
OMAi VPIVIPY.

Enzyme and pathway databases

BioCyci UMET351160:GJT4-304-MONOMER.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPi MF_00407. DNA_ligase.
InterProi IPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome of rice cluster I archaea -- the key methane producers in the rice rhizosphere."
    Erkel C., Kube M., Reinhardt R., Liesack W.
    Science 313:370-372(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiDNLI_UNCMA
AccessioniPrimary (citable) accession number: Q0W0X1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: September 5, 2006
Last modified: November 26, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3