Q0W0W0 (Q0W0W0_UNCMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401

Gene names

Name:	msrA HAMAP MF_01401 EMBL CAJ37983.1
Ordered Locus Names:	UNCMA_02830
ORF Names:	RRC241 EMBL CAJ37983.1

Organism

Uncultured methanogenic archaeon RC-I [Complete proteome] [HAMAP] EMBL CAJ37983.1

Taxonomic identifier

351160 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › environmental samples

Protein attributes

Sequence length	163 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 EMBL CAJ37983.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	19	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	Q0W0W0 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 1A44B25BDA4FFA8B	FASTA	163	18,497
	10 20 30 40 50 60 MSGERQSSKQ EKATFGAGCF WHVEDAFLKE PGVISTQSGF MGGTTENPTY EEVCTGRTGH 70 80 90 100 110 120 TEVVEVTYDP DKVTYDRLLD VFWSIHDPTQ VNRQGPDIGV QYRSVIFYHN AEQQKLAEAS 130 140 150 160 RERIQKASSK PIATSIEPAG KFYRAEEYHQ RYFEKTGRRC CGV

References

[1]	"Genome of rice cluster I archaea -- the key methane producers in the rice rhizosphere." Erkel C., Kube M., Reinhardt R., Liesack W. Science 313:370-372(2006) [PubMed: 16857943] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM114193 Genomic DNA. Translation: CAJ37983.1.
RefSeq	YP_687309.1. NC_009464.1.
3D structure databases
ProteinModelPortal	Q0W0W0.
SMR	Q0W0W0. Positions 6-159.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0W0W0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5143104.
GenomeReviews	Gene locus UNCMA_02830 in contig AM114193_GR.
KEGG	rci:RRC241.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG08844.
HOGENOM	HBG748152.
OMA	EDKIVTE.
PhylomeDB	Q0W0W0.
ProtClustDB	PRK14054.
Enzyme and pathway databases
BioCyc	UMET351160:RRC241-MONOMER.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q0W0W0_UNCMA

Accession

Primary (citable) accession number: Q0W0W0

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)