Reviewed, UniProtKB/Swiss-Prot Q0VTD7 (HEM6_ALCBS)

Names and origin

Protein names

Recommended name:
    Coproporphyrinogen-III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3

Gene names

Name:	hemF
Ordered Locus Names:	ABO_0135

Organism

Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]

Taxonomic identifier

393595 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Alcanivoracaceae › Alcanivorax

Protein attributes

Sequence length	302 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. HAMAP MF_00333
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. HAMAP MF_00333
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the aerobic coproporphyrinogen-III oxidase family.

Ontologies

Keywords
Biological process	Porphyrin biosynthesis
Cellular component	Cytoplasm
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW porphyrin biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	coproporphyrinogen oxidase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 302	302	Coproporphyrinogen-III oxidase, aerobic HAMAP MF_00333		PRO_1000119784

Sequences

	Sequence		Length	Mass (Da)
	Q0VTD7-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 8B2F3DBF3A58E31F	FASTA	302	34,744
	10 20 30 40 50 60 MSEVSLQAVK DYLLDLQDRI CDALGAEDGA ATFREDSWER EQGGGGRSRV LENGAVIEKG 70 80 90 100 110 120 GVNFSHVFGE QLPPSATEAR PELAGRSFQA MGVSLVIHPK NPYVPTSHAN VRFFVAEKEG 130 140 150 160 170 180 EAPVWWFGGG FDLTPYYGFE EDVVHWHQTA KVACQPFGKE IYPEFKTWCD DYFYLKHRNE 190 200 210 220 230 240 PRGVGGLFFD DLNRFDFDTS FALMRSIGDA YVPAYQPILA RRKDHEFGDR ERQFQLYRRG 250 260 270 280 290 300 RYVEFNLVYD RGTIFGLQSG GRTESILMSL PPLVRWDYDY HPEPNSAESE LYHKFLIHRE WV

References

[1]

"Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium Alcanivorax borkumensis." Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M., Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C., Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B., McHardy A.C., Meyer F. , Nechitaylo T., Puehler A., Regenhardt D., Rupp O., Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J., Weidner S., Kaiser O., Golyshin P.N. Nat. Biotechnol. 24:997-1004(2006) [PubMed: 16878126] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM286690 Genomic DNA. Translation: CAL15583.1.
RefSeq	YP_691855.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q0VTD7.
Genome annotation databases
GeneID	4213624.
GenomeReviews	Gene locus ABO_0135 in contig AM286690_GR.
KEGG	abo:ABO_0135.
NMPDR	fig|393595.12.peg.134.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0VTD7.
OMA	VKAYLLD.
Enzyme and pathway databases
BioCyc	ABOR393595:ABO_0135-MON.
Family and domain databases
HAMAP	MF_00333. [Tree]
InterPro	IPR001260. Coprogen_oxidas. IPR018375. Coproporphyrinogen-3_ox_CS. [Graphical view]
Gene3D	G3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHER	PTHR10755. Coprogen_oxidas. 1 hit.
Pfam	PF01218. Coprogen_oxidas. 1 hit. [Graphical view]
PIRSF	PIRSF000166. Coproporphyri_ox. 1 hit.
PRINTS	PR00073. COPRGNOXDASE.
PROSITE	PS01021. COPROGEN_OXIDASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HEM6_ALCBS

Accession

Primary (citable) accession number: Q0VTD7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	September 5, 2006
Last modified:	November 3, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)