ID   Q0VSG5_ALCBS            Unreviewed;       453 AA.
AC   Q0VSG5;
DT   05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2006, sequence version 1.
DT   27-MAR-2024, entry version 91.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAL15883.1};
DE            EC=4.6.1.1 {ECO:0000313|EMBL:CAL15883.1};
GN   OrderedLocusNames=ABO_0435 {ECO:0000313|EMBL:CAL15883.1};
OS   Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 /
OS   SK2).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Alcanivoracaceae; Alcanivorax.
OX   NCBI_TaxID=393595 {ECO:0000313|EMBL:CAL15883.1, ECO:0000313|Proteomes:UP000008871};
RN   [1] {ECO:0000313|EMBL:CAL15883.1, ECO:0000313|Proteomes:UP000008871}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2
RC   {ECO:0000313|Proteomes:UP000008871};
RX   PubMed=16878126; DOI=10.1038/nbt1232;
RA   Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M.,
RA   Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C.,
RA   Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B.,
RA   McHardy A.C., Meyer F., Nechitaylo T., Puehler A., Regenhardt D., Rupp O.,
RA   Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J.,
RA   Weidner S., Kaiser O., Golyshin P.N.;
RT   "Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium
RT   Alcanivorax borkumensis.";
RL   Nat. Biotechnol. 24:997-1004(2006).
CC   -!- SIMILARITY: Belongs to the adenylyl cyclase class-3 family.
CC       {ECO:0000256|ARBA:ARBA00005381}.
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DR   EMBL; AM286690; CAL15883.1; -; Genomic_DNA.
DR   RefSeq; WP_011587721.1; NC_008260.1.
DR   AlphaFoldDB; Q0VSG5; -.
DR   STRING; 393595.ABO_0435; -.
DR   KEGG; abo:ABO_0435; -.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG5000; Bacteria.
DR   HOGENOM; CLU_042376_0_0_6; -.
DR   OrthoDB; 9806704at2; -.
DR   Proteomes; UP000008871; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:CAL15883.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008871};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        137..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          157..209
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          243..375
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   453 AA;  49834 MW;  907E8F42FF7C7FF3 CRC64;
     MTILGTLLLN NQLSRMRDQA DSFGTAIAQQ LANTVREPLL ADDTFFLKVQ LNNLTRSESV
     RGAALFGRDG NLTDKAGILP LAASPLHEQV KRWDLEDEPI TTYYAPIKIS DVVAGHTAIS
     LSDRPIMAAR QAVRDTMITA TLIMSVIAIV VAFLISRRLA QPIHDLLAAT SAMRKGDLNY
     RIQDRRNDEI GGLIEAYNTM AHGMLEKDQV ERVLQRFVSP SVARNMMADL DQVQLGGRDV
     SATVIFADIV GFTRLSENLA PDAIADMLNV YFDAITTATS FYRGTIDKYM GDCAMIVFGV
     PEKDDEHLFH ALCCAVMIQR LVKRLNEYRN ARGETTVTFR IGINSGAMLA GNLGSRDRMQ
     YTVVGDAVNL ASRLSNMAGG NEIIAAAPLL SNPNIASRVR ATECGAMRIR GKEQPVSTHR
     IDGVHALSET LMEQRIAQFL AKLNTEHERV QGE
//