Reviewed, UniProtKB/Swiss-Prot Q0VS84 (PTH_ALCBS)

Names and origin

Protein names

Recommended name:
    Peptidyl-tRNA hydrolase
      Short name=PTH
    EC=3.1.1.29

Gene names

Name:	pth
Ordered Locus Names:	ABO_0516

Organism

Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]

Taxonomic identifier

393595 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Alcanivoracaceae › Alcanivorax

Protein attributes

Sequence length	195 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity.
Catalytic activity	N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP MF_00083
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the PTH family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	aminoacyl-tRNA hydrolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 195	195	Peptidyl-tRNA hydrolase HAMAP MF_00083		PRO_0000264000

Sequences

	Sequence		Length	Mass (Da)
	Q0VS84-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: EC91E4A06E8944EB	FASTA	195	21,465
	10 20 30 40 50 60 MADPVRLIVG LGNPGREYED TRHNAGVWYV DALARRQGVF LTEDKKYFGL TATFSFEGET 70 80 90 100 110 120 IRLLVPTTFM NRSGQATAAL ANFFKIPVTQ ILVAHDELDL PPGCARFKQG GGHGGHNGLR 130 140 150 160 170 180 DIISRHGNSR DFYRLRLGIG HPGSADRVTP HVLSKPSKAD RDLIDRAIDE AVHNTADMLR 190 GDLNSAMNRL NGFKA

References

[1]

"Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium Alcanivorax borkumensis." Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M., Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C., Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B., McHardy A.C., Meyer F. , Nechitaylo T., Puehler A., Regenhardt D., Rupp O., Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J., Weidner S., Kaiser O., Golyshin P.N. Nat. Biotechnol. 24:997-1004(2006) [PubMed: 16878126] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM286690 Genomic DNA. Translation: CAL15964.1.
RefSeq	YP_692236.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4211233.
GenomeReviews	Gene locus ABO_0516 in contig AM286690_GR.
KEGG	abo:ABO_0516.
NMPDR	fig|393595.12.peg.512.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0VS84.
OMA	Q0VS84. IKFKTGG.
Enzyme and pathway databases
BioCyc	ABOR393595:ABO_0516-MON.
Family and domain databases
HAMAP	MF_00083. [Tree]
InterPro	IPR001328. Pept_tRNA_hydro. IPR018171. Pept_tRNA_hydro_CS. [Graphical view]
Gene3D	G3DSA:3.40.50.1470. Pept_tRNA_hydro. 1 hit.
PANTHER	PTHR17224. Pept_tRNA_hydro. 1 hit.
Pfam	PF01195. Pept_tRNA_hydro. 1 hit. [Graphical view]
ProDom	PD005324. PeptRNAhydrolase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00447. pth. 1 hit.
PROSITE	PS01195. PEPT_TRNA_HYDROL_1. 1 hit. PS01196. PEPT_TRNA_HYDROL_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PTH_ALCBS

Accession

Primary (citable) accession number: Q0VS84

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	September 5, 2006
Last modified:	June 16, 2009
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)