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Q0VS40

- MURA_ALCBS

UniProt

Q0VS40 - MURA_ALCBS

Protein

UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Gene

murA

Organism
Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (05 Sep 2006)
      Previous versions | rss
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    Functioni

    Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.UniRule annotation

    Catalytic activityi

    Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei117 – 1171Proton donorUniRule annotation

    GO - Molecular functioni

    1. UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. cell cycle Source: UniProtKB-KW
    2. cell division Source: UniProtKB-KW
    3. peptidoglycan biosynthetic process Source: UniProtKB-HAMAP
    4. regulation of cell shape Source: UniProtKB-KW
    5. UDP-N-acetylgalactosamine biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Cell cycle, Cell division, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

    Keywords - Ligandi

    Pyruvate

    Enzyme and pathway databases

    BioCyciABOR393595:GHRI-577-MONOMER.
    UniPathwayiUPA00219.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UDP-N-acetylglucosamine 1-carboxyvinyltransferaseUniRule annotation (EC:2.5.1.7UniRule annotation)
    Alternative name(s):
    Enoylpyruvate transferaseUniRule annotation
    UDP-N-acetylglucosamine enolpyruvyl transferaseUniRule annotation
    Short name:
    EPTUniRule annotation
    Gene namesi
    Name:murAUniRule annotation
    Ordered Locus Names:ABO_0560
    OrganismiAlcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
    Taxonomic identifieri393595 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesAlcanivoracaceaeAlcanivorax
    ProteomesiUP000008871: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 420420UDP-N-acetylglucosamine 1-carboxyvinyltransferasePRO_1000023016Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei117 – 11712-(S-cysteinyl)pyruvic acid O-phosphothioketalUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi393595.ABO_0560.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0VS40.
    SMRiQ0VS40. Positions 1-418.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the EPSP synthase family. MurA subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0766.
    HOGENOMiHOG000075602.
    KOiK00790.
    OMAiHGLEQMG.
    OrthoDBiEOG68M4GK.

    Family and domain databases

    Gene3Di3.65.10.10. 2 hits.
    HAMAPiMF_00111. MurA.
    InterProiIPR001986. Enolpyruvate_Tfrase_dom.
    IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
    IPR005750. UDP_GlcNAc_COvinyl_MurA.
    [Graphical view]
    PANTHERiPTHR21090:SF4. PTHR21090:SF4. 1 hit.
    PfamiPF00275. EPSP_synthase. 1 hit.
    [Graphical view]
    SUPFAMiSSF55205. SSF55205. 1 hit.
    TIGRFAMsiTIGR01072. murA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q0VS40-1 [UniParc]FASTAAdd to Basket

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    MDKLIITGGQ RLDGDIRISG AKNAALPILA ATLLADEPVT VGNLPHLQDV    50
    TTLIELLGRM GVHVVIDDRM NVEVNATTIK ELTAPYELVK TMRASILVLG 100
    PMVAHFGKAS VSLPGGCAIG SRPVDIHLRG LEAMGADIEV TNGYVNASVD 150
    GRLKGARIVM DVVTVTGTEN LMMAAALAEG TTYLENAARE PEVVDLADFI 200
    NAMGGKISGA GTDTITIEGV ERLTGCHHQV IADRIETGTY LIAAAITGGR 250
    IKTKDTVPGT LDAVLQKLEE AGAKITTGDD WIELDMQGRR PKAVSLRTAP 300
    YPAMPTDMQA QFMALNLVAE GTGTIVETIF ENRFMHVQEM NRMGADIEVQ 350
    GNTAICRGVE QLTGAPVMAT DLRASASLVI AALAASGETT VDRIYHIDRG 400
    YECIEEKLQS LGAIIRRVPR 420
    Length:420
    Mass (Da):44,690
    Last modified:September 5, 2006 - v1
    Checksum:i0D07B5677C18E2BB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM286690 Genomic DNA. Translation: CAL16008.1.
    RefSeqiYP_692280.1. NC_008260.1.

    Genome annotation databases

    EnsemblBacteriaiCAL16008; CAL16008; ABO_0560.
    GeneIDi4211239.
    KEGGiabo:ABO_0560.
    PATRICi20838769. VBIAlcBor124741_0585.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM286690 Genomic DNA. Translation: CAL16008.1 .
    RefSeqi YP_692280.1. NC_008260.1.

    3D structure databases

    ProteinModelPortali Q0VS40.
    SMRi Q0VS40. Positions 1-418.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 393595.ABO_0560.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAL16008 ; CAL16008 ; ABO_0560 .
    GeneIDi 4211239.
    KEGGi abo:ABO_0560.
    PATRICi 20838769. VBIAlcBor124741_0585.

    Phylogenomic databases

    eggNOGi COG0766.
    HOGENOMi HOG000075602.
    KOi K00790.
    OMAi HGLEQMG.
    OrthoDBi EOG68M4GK.

    Enzyme and pathway databases

    UniPathwayi UPA00219 .
    BioCyci ABOR393595:GHRI-577-MONOMER.

    Family and domain databases

    Gene3Di 3.65.10.10. 2 hits.
    HAMAPi MF_00111. MurA.
    InterProi IPR001986. Enolpyruvate_Tfrase_dom.
    IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
    IPR005750. UDP_GlcNAc_COvinyl_MurA.
    [Graphical view ]
    PANTHERi PTHR21090:SF4. PTHR21090:SF4. 1 hit.
    Pfami PF00275. EPSP_synthase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55205. SSF55205. 1 hit.
    TIGRFAMsi TIGR01072. murA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SK2 / ATCC 700651 / DSM 11573.

    Entry informationi

    Entry nameiMURA_ALCBS
    AccessioniPrimary (citable) accession number: Q0VS40
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: September 5, 2006
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3