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Q0VS02 (MURG_ALCBS) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
EC=2.4.1.227
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase
Gene names
Name:murG
Ordered Locus Names:ABO_0598
OrganismAlcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]
Taxonomic identifier393595 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Alcanivoracaceae › Alcanivorax

Protein attributes

Sequence length357 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II) By similarity. HAMAP MF_00033

Catalytic activity

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP MF_00033

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00033

Subcellular location

Cell inner membrane; Peripheral membrane protein By similarity HAMAP MF_00033.

Sequence similarities

Belongs to the glycosyltransferase 28 family. MurG subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 357357UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase HAMAP MF_00033
PRO_1000002610

Sequences

Sequence LengthMass (Da)Tools
Q0VS02 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 29C2D4DE34B32ABB

FASTA35737,658
        10         20         30         40         50         60 
MSGTVLIMAG GTGGHVFPAL AVADQLRTRG FDILWLGAEN GMEGNLVRQY GYEIAELSVS 

        70         80         90        100        110        120 
RLRGGGIKRK LTAPFNLLRA VLQARQLIRA RQPVLAVGFG GFASGPGGLA ARLCKVPVVV 

       130        140        150        160        170        180 
HEQNAVPGLT NRLLSRLSTV TLEGFQGAFG HPQACWVGNP VRPQITALEE PARRYAQHQG 

       190        200        210        220        230        240 
GLRVLVLGGS QGALVLNQDL PELLLAVLGR DIQVRHQCGA GRTAEAAPIY QALGLQAQVS 

       250        260        270        280        290        300 
EFIDDMAEAY GWADLVICRA GALTVAEVAA AGVAALFVPL PSAVDDHQTL NARWLSERGA 

       310        320        330        340        350 
ALLLPQRDLG AVSLAGTLKP VAERGLLAQI AERAREQAMA DSAERAATLC EEVANGR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM286690 Genomic DNA. Translation: CAL16046.1.
RefSeqYP_692318.1. NC_008260.1.

3D structure databases

ProteinModelPortalQ0VS02.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0VS02.

Protein family/group databases

CAZyGT28. Glycosyltransferase Family 28.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4211245.
GenomeReviewsGene locus ABO_0598 in contig AM286690_GR.
KEGGabo:ABO_0598.
NMPDRfig|393595.12.peg.596.
PATRIC20838849. VBIAlcBor124741_0625.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0707.
HOGENOMHBG617076.
OMAAARLCKV.
PhylomeDBQ0VS02.

Enzyme and pathway databases

BioCycABOR393595:ABO_0598-MONOMER.

Family and domain databases

HAMAPMF_00033. MurG.
[Tree]
InterProIPR006009. GlcNAc_MurG.
IPR004276. Glyco_trans_28.
IPR007235. Glyco_trans_28_C.
[Graphical view]
KOK02563.
PANTHERPTHR21015:SF22. PTHR21015:SF22. 1 hit.
PfamPF04101. Glyco_tran_28_C. 1 hit.
PF03033. Glyco_transf_28. 1 hit.
[Graphical view]
TIGRFAMsTIGR01133. MurG. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMURG_ALCBS
AccessionPrimary (citable) accession number: Q0VS02
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 5, 2006
Last modified: January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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