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Reviewed, UniProtKB/Swiss-Prot Q0VS00 (DDL_ALCBS)

Last modified November 25, 2008. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    D-alanine--D-alanine ligase
    EC=6.3.2.4
Alternative name(s):
    D-alanylalanine synthetase
    D-Ala-D-Ala ligase
Gene names
Name: ddl
Ordered Locus Names: ABO_0600
OrganismAlcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]
Taxonomic identifier393595 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesAlcanivoracaceaeAlcanivorax

Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Cell wall formation By similarity.

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Subcellular location

CytoplasmBy similarity.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family.

Contains 1 ATP-grasp domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 307307D-alanine--D-alanine ligase
PRO_0000341048

Regions

Domain110 – 299190ATP-grasp
Nucleotide binding136 – 18550ATP By similarity

Sites

Metal binding2531Magnesium or manganese 1 By similarity
Metal binding2661Magnesium or manganese 1 By similarity
Metal binding2661Magnesium or manganese 2 By similarity
Metal binding2681Magnesium or manganese 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0VS00-1 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: CDB08412E311061A

FASTA30732,851
        10         20         30         40         50         60 
MDKRALKERL SRVGRVAVLA GGRSAERAVS LKSGAAVHAG LRNLGLLAEL VDPADKSVDT 

        70         80         90        100        110        120 
LRGFDAAFIA LHGRGGEDGV IQGVLEHLEI PYTGSGVMAS AIGMDKVRTK QLWKGAGLPT 

       130        140        150        160        170        180 
PAFYVAGREE AELGFPVIVK PAHEGSSIGM AKADNTEELG EALVAAEKFD QDVLVEAWVN 

       190        200        210        220        230        240 
GPEYTVAVLG DEALPAIRLQ TPHVFYDFEA KYQSDSTEYL CPAGLDDADE QALRTLALTA 

       250        260        270        280        290        300 
FRVAGCRGWG RVDVMRDEQG QWQLLEVNTV PGMTDHSLVP MAAKATGRDF DVLVGEILLD 


ALERGRG 

« Hide

Cross-references

Sequence databases

AM286690 Genomic DNA. Translation: CAL16048.1.
RefSeqYP_692320.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID4212209.
GenomeReviewsGene locus ABO_0600 in contig AM286690_GR.
KEGGabo:ABO_0600.
NMPDRfig|393595.12.peg.598.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ0VS00.

Enzyme and pathway databases

BioCycABOR393595:ABO_0600-MON.

Family and domain databases

HAMAPMF_00047.
[Tree]
InterProIPR011761. ATP-grasp.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR013817. Pre-ATP_grasp.
[Graphical view]
Gene3DG3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit.
G3DSA:3.40.50.20. Pre-ATP_grasp. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDDL_ALCBS
AccessionPrimary (citable) accession number: Q0VS00
Entry history
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: September 5, 2006
Last modified: November 25, 2008
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents