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Reviewed, UniProtKB/Swiss-Prot Q0VRN6 (GLPK_ALCBS)

Last modified February 9, 2010. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Glycerol kinase
    EC=2.7.1.30
Alternative name(s):
    ATP:glycerol 3-phosphotransferase
    Glycerokinase
      Short name=GK
Gene names
Name: glpK
Ordered Locus Names: ABO_0714
OrganismAlcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]
Taxonomic identifier393595 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Alcanivoracaceae › Alcanivorax

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Protein attributes

Sequence length497 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Key enzyme in the regulation of glycerol uptake and metabolism. HAMAP MF_00186

Catalytic activity

ATP + glycerol = ADP + sn-glycerol 3-phosphate. HAMAP MF_00186

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. HAMAP MF_00186

Sequence similarities

Belongs to the FGGY kinase family.

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Ontologies

Keywords
   Biological processGlycerol metabolism
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycerol-3-phosphate metabolic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionATP binding

Inferred from electronic annotation. Source: HAMAP

glycerol kinase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 497497Glycerol kinase HAMAP MF_00186
PRO_1000020695

Regions

Nucleotide binding407 – 4115ATP By similarity

Sites

Binding site111Substrate By similarity
Binding site151ATP By similarity
Binding site811Substrate By similarity
Binding site1331Substrate By similarity
Binding site2421Substrate By similarity
Binding site2641ATP By similarity
Binding site3061ATP; via carbonyl oxygen By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q0VRN6-1 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: B369FC409141A4DA

FASTA49754,056
        10         20         30         40         50         60 
MPYILSIDQG TTSSRAIVFD ANGHACGQAQ KEFRQYFPED GWVEHDAMEI WNDTLAMCQQ 

        70         80         90        100        110        120 
ALRNARVEAQ QLVAIGITNQ RETTVLWDRE TGDPLARAIV WQDRRTASTC EALRDQGHEN 

       130        140        150        160        170        180 
QVRSKTGLLL DPYFSATKLA WLLDNVPNAR QRAEAGELAF GTIDSWLLWQ LTRGKVHATD 

       190        200        210        220        230        240 
ATNASRTLLF NIHEQCWDEE LLTLFNVPAS VLPDVRDSAA DFGTTCPELL GAAVPVTGIA 

       250        260        270        280        290        300 
GDQQAALVGQ ACFAPGMVKS TYGTGCFMVM NTGEAVESHN RLLTTVGYRL NGKTTYALEG 

       310        320        330        340        350        360 
SIFVAGAAIQ WLRDGLHLIR DARETEALAR RVGSAGGVYL VPAFTGLGAP WWDPHARGAL 

       370        380        390        400        410        420 
MGLTRDTGIA EVVTAGLEAV CYQSRDLLDA MAADCGTRPT TLRVDGGMVV NNWLSQTLSD 

       430        440        450        460        470        480 
VLGVCVDRPV VTETTALGAA YLAGLGVGLY ASLESIAEQW RCERGFSPAL AEPERQKRYQ 

       490 
GWRDAVARVC QTSRGAN

« Hide

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM286690 Genomic DNA. Translation: CAL16162.1.
RefSeqYP_692434.1.

3D structure databases

SMRQ0VRN6. Positions 3-490.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0VRN6.

Genome annotation databases

GeneID4211193.
GenomeReviewsGene locus ABO_0714 in contig AM286690_GR.
KEGGabo:ABO_0714.
NMPDRfig|393595.12.peg.715.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0554.
HOGENOMHBG511469.
OMAKMAGSAQ.
PhylomeDBQ0VRN6.

Enzyme and pathway databases

BioCycABOR393595:ABO_0714-MONOMER.

Family and domain databases

HAMAPMF_00186. Glycerol_kin.
[Tree]
InterProIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR005999. Glycerol_kin.
[Graphical view]
PANTHERPTHR10196. FGGY_kin. 1 hit.
PTHR10196:SF9. Glycerol_kin. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01311. glycerol_kin. 1 hit.
PROSITEPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. False negative.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameGLPK_ALCBS
AccessionPrimary (citable) accession number: Q0VRN6
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 5, 2006
Last modified: February 9, 2010
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents