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Q0VRM5

- ASSY_ALCBS

UniProt

Q0VRM5 - ASSY_ALCBS

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Protein

Argininosuccinate synthase

Gene
argG, ABO_0725
Organism
Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei37 – 371ATP; via amide nitrogen and carbonyl oxygen By similarity
Binding sitei88 – 881Citrulline By similarity
Binding sitei93 – 931Citrulline By similarity
Binding sitei118 – 1181ATP; via amide nitrogen By similarity
Binding sitei120 – 1201Aspartate By similarity
Binding sitei124 – 1241Aspartate By similarity
Binding sitei124 – 1241Citrulline By similarity
Binding sitei125 – 1251Aspartate By similarity
Binding sitei128 – 1281Citrulline By similarity
Binding sitei180 – 1801Citrulline By similarity
Binding sitei189 – 1891Citrulline By similarity
Binding sitei265 – 2651Citrulline By similarity
Binding sitei277 – 2771Citrulline By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 189ATP By similarity

GO - Molecular functioni

  1. argininosuccinate synthase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciABOR393595:GHRI-743-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthase (EC:6.3.4.5)
Alternative name(s):
Citrulline--aspartate ligase
Gene namesi
Name:argG
Ordered Locus Names:ABO_0725
OrganismiAlcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
Taxonomic identifieri393595 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesAlcanivoracaceaeAlcanivorax
ProteomesiUP000008871: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 407407Argininosuccinate synthaseUniRule annotationPRO_0000263904Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi393595.ABO_0725.

Structurei

3D structure databases

ProteinModelPortaliQ0VRM5.
SMRiQ0VRM5. Positions 6-404.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230093.
KOiK01940.
OMAiPECEYIR.
OrthoDBiEOG6K9QCV.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0VRM5-1 [UniParc]FASTAAdd to Basket

« Hide

MSKINKVVLA YSGGLDTSVI VKWLQDTYDC EVVTFTADIG QGEEVEPARA    50
KAEAMGVKEI YIEDLREEFV RDYVFPMFRA NAIYEGEYLL GTSIARPLIA 100
KRLVEIAEET GADAISHGAT GKGNDQVRFE LGAYALAPGI QVIAPWREWD 150
LNSREKLMAY CEERNIPVDF SNKKKKSPYS MDANLLHISY EGGNLEDPWW 200
EAEEDMWRWS VSPEAAPDQA TYITLGFEKG DIVSIDGETL SPADVLTKLN 250
KLGGDNGIGR LDIVENRYVG MKSRGCYETP GGTIMLPAHR AIESLTLDRE 300
SAHLKDSVMP KYAELLYNGY WWSPERLALQ KLIDATQEHV NGEVRLKLYK 350
GSVTVVGRRS DNDSLFDASI ATFEDDAGAY DQKDAEGFIK LNALRLRIAA 400
KTGRKLS 407
Length:407
Mass (Da):45,442
Last modified:September 5, 2006 - v1
Checksum:iEE3253CE29FDE9D6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM286690 Genomic DNA. Translation: CAL16173.1.
RefSeqiWP_011588009.1. NC_008260.1.
YP_692445.1. NC_008260.1.

Genome annotation databases

EnsemblBacteriaiCAL16173; CAL16173; ABO_0725.
GeneIDi4213481.
KEGGiabo:ABO_0725.
PATRICi20839125. VBIAlcBor124741_0762.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM286690 Genomic DNA. Translation: CAL16173.1 .
RefSeqi WP_011588009.1. NC_008260.1.
YP_692445.1. NC_008260.1.

3D structure databases

ProteinModelPortali Q0VRM5.
SMRi Q0VRM5. Positions 6-404.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 393595.ABO_0725.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAL16173 ; CAL16173 ; ABO_0725 .
GeneIDi 4213481.
KEGGi abo:ABO_0725.
PATRICi 20839125. VBIAlcBor124741_0762.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230093.
KOi K01940.
OMAi PECEYIR.
OrthoDBi EOG6K9QCV.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci ABOR393595:GHRI-743-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SK2 / ATCC 700651 / DSM 11573.

Entry informationi

Entry nameiASSY_ALCBS
AccessioniPrimary (citable) accession number: Q0VRM5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: September 5, 2006
Last modified: September 3, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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