Reviewed, UniProtKB/Swiss-Prot Q0VR14 (G6PI_ALCBS)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase
      Short name=GPI
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase
      Short name=PGI
    Phosphohexose isomerase
      Short name=PHI

Gene names

Name:	pgi
Ordered Locus Names:	ABO_0936

Organism

Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]

Taxonomic identifier

393595 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Alcanivoracaceae › Alcanivorax

Protein attributes

Sequence length	548 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity HAMAP MF_00473.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 548	548	Glucose-6-phosphate isomerase HAMAP MF_00473		PRO_0000252606
Sites
	Active site	356	1	Proton donor By similarity
	Active site	387	1	By similarity
	Active site	511	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0VR14-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: C0BAD4A364DC5A10	FASTA	548	60,524
	10 20 30 40 50 60 MVPEQNDLTE SSVWLQLENL AREEGSLHLS DFFVQELGRC AHFCLESDGL LVDLSKQRVS 70 80 90 100 110 120 SHARDLLVSL ADERGLDRWS EALFAGAEVN CTENRSAKHW LLRDPSDQAA EIHGQLEIMD 130 140 150 160 170 180 SIVSRVLEGQ WRGVLGDAIT DVVNVGVGGS ELGPLMAAFA LHSTPLAEGE VRPSLHFASS 190 200 210 220 230 240 MDGSQISQVL QELNPRTTLV LVSSKSFTTV DTLHNANTAR SWMARALGLE MDNEAMLRCH 250 260 270 280 290 300 FIGISAQPDK MTAWGIPSTN QLQFWDWVGG RYSLWSAIGL PIALTVGMHG FRELLAGAHD 310 320 330 340 350 360 MDLHFRQRPW HENIPVMLAL VDVWNINFLD IRARAVLPYD GRLKYLPAYL EQLEMESNGK 370 380 390 400 410 420 SVSRNGDPVD YHTCPVIWGE VGPNAQHAFF QLLHQGTQPV ACEFLMTARR YTESAHSGAA 430 440 450 460 470 480 VELEGQHALS NANCLAQSRL LAFGEQALDS TLALPAYKRY RGNQPSTTLV LDELSPRTLG 490 500 510 520 530 540 SLLAMYEHKV FAQAVIWGIN PFDQWGVEMG KVIATDMLAV LADPDGAHEV DDSSLSLARH IACKQATQ

References

[1]

"Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium Alcanivorax borkumensis." Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M., Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C., Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B., McHardy A.C., Meyer F. , Nechitaylo T., Puehler A., Regenhardt D., Rupp O., Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J., Weidner S., Kaiser O., Golyshin P.N. Nat. Biotechnol. 24:997-1004(2006) [PubMed: 16878126] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM286690 Genomic DNA. Translation: CAL16384.1.
RefSeq	YP_692656.1.
3D structure databases
SMR	Q0VR14. Positions 7-543.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0VR14.
Genome annotation databases
GeneID	4211325.
GenomeReviews	Gene locus ABO_0936 in contig AM286690_GR.
KEGG	abo:ABO_0936.
NMPDR	fig|393595.12.peg.937.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0166.
HOGENOM	HBG352954.
OMA	SFTTIDT.
PhylomeDB	Q0VR14.
Enzyme and pathway databases
BioCyc	ABOR393595:ABO_0936-MONOMER.
Family and domain databases
HAMAP	MF_00473. G6P_isomerase. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI_ALCBS

Accession

Primary (citable) accession number: Q0VR14

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 17, 2006
Last sequence update:	September 5, 2006
Last modified:	January 19, 2010
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)