Reviewed, UniProtKB/Swiss-Prot Q0VQV5 (PPNK_ALCBS)

Names and origin

Protein names

Recommended name:
    Probable inorganic polyphosphate/ATP-NAD kinase
      Short name=Poly(P)/ATP NAD kinase
    EC=2.7.1.23

Gene names

Name:	ppnK
Ordered Locus Names:	ABO_0995

Organism

Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]

Taxonomic identifier

393595 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Alcanivoracaceae › Alcanivorax

Protein attributes

Sequence length	300 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity.
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 300	300	Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361		PRO_1000079479

Sequences

	Sequence		Length	Mass (Da)
	Q0VQV5-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 185980257583C98E	FASTA	300	32,683
	10 20 30 40 50 60 MRSLVAQEKF RNIGLIARSE SEQALYSLRQ LIHFLHGRDC TVILDKHIIG HLPEMGLQAA 70 80 90 100 110 120 SASQMGEACD LVIVVGGDGS LLGAARTLAR YKVPVLGVNR GHLGFLTDIL PSEIESRVGQ 130 140 150 160 170 180 VLDGEYSTEK RFLLDLEVRR GRTVVGEGSA LNDIVLLSGD SVHMIDFELM IDGHFVYGQR 190 200 210 220 230 240 SDGLIVSTPT GSTAYALSGG GPIMHPKLDA MVLVPLNPHT LTSRPLVVAG DSEIKIHITT 250 260 270 280 290 300 EKVRPLVSCD GTEGIRLQVD DVIAIRKKPH RLHLIHPPGH DFYQACRSKL GWSSRPGDNN

References

[1]

"Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium Alcanivorax borkumensis." Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M., Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C., Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B., McHardy A.C., Meyer F. , Nechitaylo T., Puehler A., Regenhardt D., Rupp O., Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J., Weidner S., Kaiser O., Golyshin P.N. Nat. Biotechnol. 24:997-1004(2006) [PubMed: 16878126] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM286690 Genomic DNA. Translation: CAL16443.1.
RefSeq	YP_692715.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q0VQV5.
Genome annotation databases
GeneID	4211794.
GenomeReviews	Gene locus ABO_0995 in contig AM286690_GR.
KEGG	abo:ABO_0995.
NMPDR	fig|393595.12.peg.1002.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0VQV5.
OMA	MEQFRNI.
Enzyme and pathway databases
BioCyc	ABOR393595:ABO_0995-MON.
Family and domain databases
HAMAP	MF_00361. [Tree]
InterPro	IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. ATP_NADK. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PPNK_ALCBS

Accession

Primary (citable) accession number: Q0VQV5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	September 5, 2006
Last modified:	November 3, 2009
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)