Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q0VQT2

- Q0VQT2_ALCBS

UniProt

Q0VQT2 - Q0VQT2_ALCBS

Protein

Beta-hexosaminidase

Gene

nagZ

Organism
Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (05 Sep 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.UniRule annotation

    Catalytic activityi

    Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei74 – 741SubstrateUniRule annotation
    Binding sitei82 – 821SubstrateUniRule annotation
    Binding sitei148 – 1481SubstrateUniRule annotation
    Sitei189 – 1891Important for catalytic activityUniRule annotation
    Active sitei191 – 1911Proton donor/acceptorUniRule annotation
    Active sitei261 – 2611NucleophileUniRule annotation

    GO - Molecular functioni

    1. beta-N-acetylhexosaminidase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro
    2. cell cycle Source: UniProtKB-KW
    3. cell division Source: UniProtKB-KW
    4. peptidoglycan biosynthetic process Source: UniProtKB-KW
    5. peptidoglycan turnover Source: UniProtKB-HAMAP
    6. regulation of cell shape Source: UniProtKB-KW

    Keywords - Molecular functioni

    GlycosidaseUniRule annotationSAAS annotationImported, Hydrolase

    Keywords - Biological processi

    Cell cycle, Cell divisionUniRule annotationSAAS annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotationSAAS annotation, Peptidoglycan synthesisUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciABOR393595:GHRI-1045-MONOMER.
    UniPathwayiUPA00544.

    Protein family/group databases

    CAZyiGH3. Glycoside Hydrolase Family 3.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Beta-hexosaminidaseUniRule annotation (EC:3.2.1.52UniRule annotation)
    Alternative name(s):
    Beta-N-acetylhexosaminidaseUniRule annotation
    N-acetyl-beta-glucosaminidaseUniRule annotation
    Gene namesi
    Name:nagZUniRule annotation
    Ordered Locus Names:ABO_1018Imported
    OrganismiAlcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)Imported
    Taxonomic identifieri393595 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesAlcanivoracaceaeAlcanivorax
    ProteomesiUP000008871: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi393595.ABO_1018.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0VQT2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni178 – 1792Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1472.
    HOGENOMiHOG000248526.
    KOiK01207.
    OMAiAHDIDLS.
    OrthoDBiEOG6BCT06.

    Family and domain databases

    Gene3Di3.20.20.300. 1 hit.
    HAMAPiMF_00364. NagZ.
    InterProiIPR022956. Beta_hexosaminidase_bac.
    IPR001764. Glyco_hydro_3_N.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF00933. Glyco_hydro_3. 1 hit.
    [Graphical view]
    SUPFAMiSSF51445. SSF51445. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q0VQT2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSVYKVAMS ASASPLLMLD LEGLEVSASE KDMLAHPGAG GLILFARNYV    50
    DRQQLAELVQ QVRAVRPEML IAVDQEGGRV QRFRDGFVRL PPMAALGQRY 100
    DQAPAQAVGE ATLLGELMAS ELTELDIDIS FAPVLDLDYG NSSVIGDRSF 150
    HGDADAMIAL AGAFIDGMSA AGMAATGKHF PGHGHVGADS HLELPIDPRP 200
    LSELEAADMR PFMALAPKLD GIMPAHVIYS AVEQQTAGFS RYWLQTQLRE 250
    RLGFRGVIFS DDLSMAGAHG VGGYPQRAQA ALEAGCDMVL ACNCCEGAEQ 300
    VLDFLGTQNF SGQVPAAGLR ARPRLPMDAQ RRAVAADLAA ALREH 345
    Length:345
    Mass (Da):36,802
    Last modified:September 5, 2006 - v1
    Checksum:i358CF6114C414B4C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM286690 Genomic DNA. Translation: CAL16466.1.
    RefSeqiWP_011588302.1. NC_008260.1.
    YP_692738.1. NC_008260.1.

    Genome annotation databases

    EnsemblBacteriaiCAL16466; CAL16466; ABO_1018.
    GeneIDi4211415.
    KEGGiabo:ABO_1018.
    PATRICi20839759. VBIAlcBor124741_1070.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM286690 Genomic DNA. Translation: CAL16466.1 .
    RefSeqi WP_011588302.1. NC_008260.1.
    YP_692738.1. NC_008260.1.

    3D structure databases

    ProteinModelPortali Q0VQT2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 393595.ABO_1018.

    Protein family/group databases

    CAZyi GH3. Glycoside Hydrolase Family 3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAL16466 ; CAL16466 ; ABO_1018 .
    GeneIDi 4211415.
    KEGGi abo:ABO_1018.
    PATRICi 20839759. VBIAlcBor124741_1070.

    Phylogenomic databases

    eggNOGi COG1472.
    HOGENOMi HOG000248526.
    KOi K01207.
    OMAi AHDIDLS.
    OrthoDBi EOG6BCT06.

    Enzyme and pathway databases

    UniPathwayi UPA00544 .
    BioCyci ABOR393595:GHRI-1045-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.300. 1 hit.
    HAMAPi MF_00364. NagZ.
    InterProi IPR022956. Beta_hexosaminidase_bac.
    IPR001764. Glyco_hydro_3_N.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF00933. Glyco_hydro_3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51445. SSF51445. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SK2 / ATCC 700651 / DSM 11573Imported.

    Entry informationi

    Entry nameiQ0VQT2_ALCBS
    AccessioniPrimary (citable) accession number: Q0VQT2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 5, 2006
    Last sequence update: September 5, 2006
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3