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Q0VQ19

- Q0VQ19_ALCBS

UniProt

Q0VQ19 - Q0VQ19_ALCBS

Protein
Submitted name:

Isocitrate dehydrogenase (NADP-dependent)

Gene

icd

Organism
Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (05 Sep 2006)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei145 – 1451Substrate
    Sitei255 – 2551Critical for catalysisUniRule annotation
    Metal bindingi350 – 3501Magnesium or manganeseUniRule annotation
    Sitei420 – 4201Critical for catalysisUniRule annotation
    Binding sitei547 – 5471SubstrateUniRule annotation
    Metal bindingi548 – 5481Magnesium or manganeseUniRule annotation
    Metal bindingi552 – 5521Magnesium or manganeseUniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciABOR393595:GHRI-1312-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase (NADP-dependent)Imported (EC:1.1.1.42Imported)
    Gene namesi
    Name:icdImported
    Ordered Locus Names:ABO_1281Imported
    OrganismiAlcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)Imported
    Taxonomic identifieri393595 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesAlcanivoracaceaeAlcanivorax
    ProteomesiUP000008871: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi393595.ABO_1281.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0VQ19.
    SMRiQ0VQ19. Positions 3-740.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni132 – 1398Substrate binding

    Phylogenomic databases

    eggNOGiCOG2838.
    HOGENOMiHOG000240860.
    KOiK00031.
    OMAiYSMERAI.
    OrthoDBiEOG6DVJPP.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q0VQ19-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTTPKIIYTM TDEAPALATY SFLPIIEKFT SIAGIEVESS DISLATRILA    50
    SFPEYLSEQQ KVKDTLSELS DLTQDPEANI IKLPNISASI PQLREAIAEL 100
    NEHGYAVPEY PDEPQNEKEK DIQARYTKIL GSAVNPVLRE GNSDRRAPIA 150
    VKNYARKNPH SMGYWSPASR THVAHMRGGD FFSHETSCTI DKACKVRIEF 200
    EDSNGNITVK KPDLALLDGE VIDAMYMSKK ALCAFFDEQI EDAKNTGMLF 250
    SLHVKATMMK VSHPIVFGHA VRCFYRELFE KHGEILEKIG ANPNNGLSNI 300
    YQKIEELPIS QRLEIESTIR ACYLHRPELA MVDSDRGISN LHVPSDVIVD 350
    ASMPAMIRQG GKMYGADGKL KDTKAVIPES TYATIYQEVI NFCKTHGAFD 400
    PVTCGSVPNV GLMAQKAEEY GSHDKTFEAT ADGSMRIVRE DGEVLLTHKV 450
    EQGDIWRMCQ AKDLPIRDWV KLAVVRARLS NTPAIFWLDK ERAHDAQLIL 500
    KVKEYLKDHD TEGLDIRIMS PVQAIRYTME RMIRGKDTIS VTGNVLRDYL 550
    TDLFPILELG TSAKMLSIVP LMAGGGLYET GAGGSAPKHV QQFLEENHLR 600
    WDSLGEFLAL SVSIQELGEK YGNKKAKVIA AALDKANEQY LEQNKSPSRK 650
    VGQPDNRVSH FYVAMYWAQA LAAQDDDAEL KEKFTEIASS LSQNEEKIVK 700
    EMVAVQGSPI DIGGYYNPDF NKASQAMRPS GTFNQILEKL 740
    Length:740
    Mass (Da):82,598
    Last modified:September 5, 2006 - v1
    Checksum:iE93E9721F03991CC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM286690 Genomic DNA. Translation: CAL16729.1.
    RefSeqiYP_693001.1. NC_008260.1.

    Genome annotation databases

    EnsemblBacteriaiCAL16729; CAL16729; ABO_1281.
    GeneIDi4211344.
    KEGGiabo:ABO_1281.
    PATRICi20840317. VBIAlcBor124741_1345.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM286690 Genomic DNA. Translation: CAL16729.1 .
    RefSeqi YP_693001.1. NC_008260.1.

    3D structure databases

    ProteinModelPortali Q0VQ19.
    SMRi Q0VQ19. Positions 3-740.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 393595.ABO_1281.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAL16729 ; CAL16729 ; ABO_1281 .
    GeneIDi 4211344.
    KEGGi abo:ABO_1281.
    PATRICi 20840317. VBIAlcBor124741_1345.

    Phylogenomic databases

    eggNOGi COG2838.
    HOGENOMi HOG000240860.
    KOi K00031.
    OMAi YSMERAI.
    OrthoDBi EOG6DVJPP.

    Enzyme and pathway databases

    BioCyci ABOR393595:GHRI-1312-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SK2 / ATCC 700651 / DSM 11573Imported.

    Entry informationi

    Entry nameiQ0VQ19_ALCBS
    AccessioniPrimary (citable) accession number: Q0VQ19
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 5, 2006
    Last sequence update: September 5, 2006
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3