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Protein
Submitted name:

Isocitrate dehydrogenase (NADP-dependent)

Gene

icd

Organism
Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Cofactori

Mg2+UniRule annotation, Mn2+UniRule annotationNote: Binds 1 Mg(2+) or Mn2+ ion per subunit.UniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciABOR393595:GHRI-1312-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase (NADP-dependent)Imported (EC:1.1.1.42Imported)
Gene namesi
Name:icdImported
Ordered Locus Names:ABO_1281Imported
OrganismiAlcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)Imported
Taxonomic identifieri393595 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesAlcanivoracaceaeAlcanivorax
ProteomesiUP000008871: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi393595.ABO_1281.

Structurei

3D structure databases

ProteinModelPortaliQ0VQ19.
SMRiQ0VQ19. Positions 3-740.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiNSGQMWG.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0VQ19-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTTPKIIYTM TDEAPALATY SFLPIIEKFT SIAGIEVESS DISLATRILA
60 70 80 90 100
SFPEYLSEQQ KVKDTLSELS DLTQDPEANI IKLPNISASI PQLREAIAEL
110 120 130 140 150
NEHGYAVPEY PDEPQNEKEK DIQARYTKIL GSAVNPVLRE GNSDRRAPIA
160 170 180 190 200
VKNYARKNPH SMGYWSPASR THVAHMRGGD FFSHETSCTI DKACKVRIEF
210 220 230 240 250
EDSNGNITVK KPDLALLDGE VIDAMYMSKK ALCAFFDEQI EDAKNTGMLF
260 270 280 290 300
SLHVKATMMK VSHPIVFGHA VRCFYRELFE KHGEILEKIG ANPNNGLSNI
310 320 330 340 350
YQKIEELPIS QRLEIESTIR ACYLHRPELA MVDSDRGISN LHVPSDVIVD
360 370 380 390 400
ASMPAMIRQG GKMYGADGKL KDTKAVIPES TYATIYQEVI NFCKTHGAFD
410 420 430 440 450
PVTCGSVPNV GLMAQKAEEY GSHDKTFEAT ADGSMRIVRE DGEVLLTHKV
460 470 480 490 500
EQGDIWRMCQ AKDLPIRDWV KLAVVRARLS NTPAIFWLDK ERAHDAQLIL
510 520 530 540 550
KVKEYLKDHD TEGLDIRIMS PVQAIRYTME RMIRGKDTIS VTGNVLRDYL
560 570 580 590 600
TDLFPILELG TSAKMLSIVP LMAGGGLYET GAGGSAPKHV QQFLEENHLR
610 620 630 640 650
WDSLGEFLAL SVSIQELGEK YGNKKAKVIA AALDKANEQY LEQNKSPSRK
660 670 680 690 700
VGQPDNRVSH FYVAMYWAQA LAAQDDDAEL KEKFTEIASS LSQNEEKIVK
710 720 730 740
EMVAVQGSPI DIGGYYNPDF NKASQAMRPS GTFNQILEKL
Length:740
Mass (Da):82,598
Last modified:September 5, 2006 - v1
Checksum:iE93E9721F03991CC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286690 Genomic DNA. Translation: CAL16729.1.
RefSeqiWP_011588564.1. NC_008260.1.
YP_693001.1. NC_008260.1.

Genome annotation databases

EnsemblBacteriaiCAL16729; CAL16729; ABO_1281.
GeneIDi4211344.
KEGGiabo:ABO_1281.
PATRICi20840317. VBIAlcBor124741_1345.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286690 Genomic DNA. Translation: CAL16729.1.
RefSeqiWP_011588564.1. NC_008260.1.
YP_693001.1. NC_008260.1.

3D structure databases

ProteinModelPortaliQ0VQ19.
SMRiQ0VQ19. Positions 3-740.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi393595.ABO_1281.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL16729; CAL16729; ABO_1281.
GeneIDi4211344.
KEGGiabo:ABO_1281.
PATRICi20840317. VBIAlcBor124741_1345.

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiNSGQMWG.
OrthoDBiEOG6DVJPP.

Enzyme and pathway databases

BioCyciABOR393595:GHRI-1312-MONOMER.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SK2 / ATCC 700651 / DSM 11573Imported.

Entry informationi

Entry nameiQ0VQ19_ALCBS
AccessioniPrimary (citable) accession number: Q0VQ19
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: February 4, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.