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Q0VQ19

- Q0VQ19_ALCBS

UniProt

Q0VQ19 - Q0VQ19_ALCBS

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Protein
Submitted name:

Isocitrate dehydrogenase (NADP-dependent)

Gene
icd, ABO_1281
Organism
Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei145 – 1451Substrate By similarityUniRule annotation
Sitei255 – 2551Critical for catalysis By similarityUniRule annotation
Metal bindingi350 – 3501Magnesium or manganese By similarityUniRule annotation
Sitei420 – 4201Critical for catalysis By similarityUniRule annotation
Binding sitei547 – 5471Substrate By similarityUniRule annotation
Metal bindingi548 – 5481Magnesium or manganese By similarityUniRule annotation
Metal bindingi552 – 5521Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciABOR393595:GHRI-1312-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase (NADP-dependent)Imported (EC:1.1.1.42Imported)
Gene namesi
Name:icdImported
Ordered Locus Names:ABO_1281Imported
OrganismiAlcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)Imported
Taxonomic identifieri393595 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesAlcanivoracaceaeAlcanivorax
ProteomesiUP000008871: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi393595.ABO_1281.

Structurei

3D structure databases

ProteinModelPortaliQ0VQ19.
SMRiQ0VQ19. Positions 3-740.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni132 – 1398Substrate binding By similarityUniRule annotation

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiYSMERAI.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0VQ19-1 [UniParc]FASTAAdd to Basket

« Hide

MTTPKIIYTM TDEAPALATY SFLPIIEKFT SIAGIEVESS DISLATRILA    50
SFPEYLSEQQ KVKDTLSELS DLTQDPEANI IKLPNISASI PQLREAIAEL 100
NEHGYAVPEY PDEPQNEKEK DIQARYTKIL GSAVNPVLRE GNSDRRAPIA 150
VKNYARKNPH SMGYWSPASR THVAHMRGGD FFSHETSCTI DKACKVRIEF 200
EDSNGNITVK KPDLALLDGE VIDAMYMSKK ALCAFFDEQI EDAKNTGMLF 250
SLHVKATMMK VSHPIVFGHA VRCFYRELFE KHGEILEKIG ANPNNGLSNI 300
YQKIEELPIS QRLEIESTIR ACYLHRPELA MVDSDRGISN LHVPSDVIVD 350
ASMPAMIRQG GKMYGADGKL KDTKAVIPES TYATIYQEVI NFCKTHGAFD 400
PVTCGSVPNV GLMAQKAEEY GSHDKTFEAT ADGSMRIVRE DGEVLLTHKV 450
EQGDIWRMCQ AKDLPIRDWV KLAVVRARLS NTPAIFWLDK ERAHDAQLIL 500
KVKEYLKDHD TEGLDIRIMS PVQAIRYTME RMIRGKDTIS VTGNVLRDYL 550
TDLFPILELG TSAKMLSIVP LMAGGGLYET GAGGSAPKHV QQFLEENHLR 600
WDSLGEFLAL SVSIQELGEK YGNKKAKVIA AALDKANEQY LEQNKSPSRK 650
VGQPDNRVSH FYVAMYWAQA LAAQDDDAEL KEKFTEIASS LSQNEEKIVK 700
EMVAVQGSPI DIGGYYNPDF NKASQAMRPS GTFNQILEKL 740
Length:740
Mass (Da):82,598
Last modified:September 5, 2006 - v1
Checksum:iE93E9721F03991CC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM286690 Genomic DNA. Translation: CAL16729.1.
RefSeqiYP_693001.1. NC_008260.1.

Genome annotation databases

EnsemblBacteriaiCAL16729; CAL16729; ABO_1281.
GeneIDi4211344.
KEGGiabo:ABO_1281.
PATRICi20840317. VBIAlcBor124741_1345.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM286690 Genomic DNA. Translation: CAL16729.1 .
RefSeqi YP_693001.1. NC_008260.1.

3D structure databases

ProteinModelPortali Q0VQ19.
SMRi Q0VQ19. Positions 3-740.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 393595.ABO_1281.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAL16729 ; CAL16729 ; ABO_1281 .
GeneIDi 4211344.
KEGGi abo:ABO_1281.
PATRICi 20840317. VBIAlcBor124741_1345.

Phylogenomic databases

eggNOGi COG2838.
HOGENOMi HOG000240860.
KOi K00031.
OMAi YSMERAI.
OrthoDBi EOG6DVJPP.

Enzyme and pathway databases

BioCyci ABOR393595:GHRI-1312-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SK2 / ATCC 700651 / DSM 11573.

Entry informationi

Entry nameiQ0VQ19_ALCBS
AccessioniPrimary (citable) accession number: Q0VQ19
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: July 9, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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