Q0VPK2 (RLMG_ALCBS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA large subunit methyltransferase G
EC=2.1.1.174

Alternative name(s):
23S rRNA m2G1835 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RlmG

Gene names

Name:	rlmG
Ordered Locus Names:	ABO_1448

Organism

Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]

Taxonomic identifier

393595 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Alcanivoracaceae › Alcanivorax

Protein attributes

Sequence length	390 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA By similarity. HAMAP MF_01859
Catalytic activity	S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1835) in 23S rRNA. HAMAP MF_01859
Subcellular location	Cytoplasm Potential HAMAP MF_01859.
Sequence similarities	Belongs to the methyltransferase superfamily. RlmG family.
Sequence caution	The sequence CAL16896.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nucleic acid binding Inferred from electronic annotation. Source: InterPro rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 390	390	Ribosomal RNA large subunit methyltransferase G HAMAP MF_01859		PRO_0000366446

Sequences

	Sequence		Length	Mass (Da)
	Q0VPK2 [UniParc]. Last modified March 24, 2009. Version 2. Checksum: 0968F8A99CB63AD2	FASTA	390	42,885
	10 20 30 40 50 60 MTPFHHPWGE LCLQRWPRRR NETLQAWDNA DLYLLNTLAE RGQALGNGDN APKTLVLNDQ 70 80 90 100 110 120 QGALCLALQQ AAASALDIES SGDSYTAAAA ARANAVDNGL DPNLLFCWPL DAPKQSPDQV 130 140 150 160 170 180 IMRVPKSIAL LQWQLQWLSG HLPKGVPIWL AGMDKHLPRQ LVPLMQRYLG NGRAEYGWKK 190 200 210 220 230 240 ARLFSAQAPG RVLADTDYPC RVDALQWRLT VHAGVFAQQQ LDIGARFFLD HLPEALHTGA 250 260 270 280 290 300 KVADLGCGNG VIGMAVLKAN PAARVTFCDE SWLALESARD NVSRYFSDAE SHFHLGDGLA 310 320 330 340 350 360 GLEQRFDCIL LNPPFHDGYV VGDHVARRLF NQAATALVPG GELRVIGNRH LGYHKVLARR 370 380 390 FTSVTVLASN AKFVVWRCQG PTPSASNPLD

References

[1]

"Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium Alcanivorax borkumensis." Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M., Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C., Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B., McHardy A.C., Meyer F. , Nechitaylo T., Puehler A., Regenhardt D., Rupp O., Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J., Weidner S., Kaiser O., Golyshin P.N. Nat. Biotechnol. 24:997-1004(2006) [PubMed: 16878126] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SK2 / ATCC 700651 / DSM 11573.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM286690 Genomic DNA. Translation: CAL16896.1. Different initiation.
RefSeq	YP_693168.1. NC_008260.1.
3D structure databases
ProteinModelPortal	Q0VPK2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0VPK2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4212572.
GenomeReviews	Gene locus ABO_1448 in contig AM286690_GR.
KEGG	abo:ABO_1448.
NMPDR	fig|393595.12.peg.1454.
PATRIC	20840675. VBIAlcBor124741_1520.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2813.
HOGENOM	HBG321931.
Enzyme and pathway databases
BioCyc	ABOR393595:ABO_1448-MONOMER.
Family and domain databases
HAMAP	MF_01859. 23SrRNA_methyltr_G. [Tree]
InterPro	IPR002052. DNA_methylase_N6_adenine_CS. IPR017237. rRNA_m2G-MeTrfase_RsmD. IPR007848. Small_mtfrase. [Graphical view]
KO	K00564.
Pfam	PF05175. MTS. 1 hit. [Graphical view]
PIRSF	PIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMG_ALCBS

Accession

Primary (citable) accession number: Q0VPK2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	March 24, 2009
Last modified:	January 25, 2012
This is version 39 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program