Reviewed, UniProtKB/Swiss-Prot Q0VPI8 (TRPF_ALCBS)

Names and origin

Protein names

Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomerase
      Short name=PRAI
    EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	ABO_1462

Organism

Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]

Taxonomic identifier

393595 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Alcanivoracaceae › Alcanivorax

Protein attributes

Sequence length	218 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP MF_00135
Sequence similarities	Belongs to the trpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 218	218	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP MF_00135		PRO_1000018575

Sequences

	Sequence		Length	Mass (Da)
	Q0VPI8-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: DC0D0E5C2BE36734	FASTA	218	22,908
	10 20 30 40 50 60 MTVPRVKICG ITRIEDGLAA ANAGADAIGL VFYGPSPRAV TARQAAEICA SLPPFVTTVA 70 80 90 100 110 120 LFVDASRAEI EGVLARVPVD LLQFHGNENP QFCDSFNRPW IKAVRMKDDV DLHHYAQIYR 130 140 150 160 170 180 NAAGLLIDSY VAGVPGGTGE TFNWGRVPKT LPLPVVLAGG LHPGNVAAAV TQVQPWAVDV 190 200 210 SGGVEQKNVQ GGRSGGIKDA SAIRVFINSV KTRGVAGV

References

[1]

"Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium Alcanivorax borkumensis." Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M., Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C., Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B., McHardy A.C., Meyer F. , Nechitaylo T., Puehler A., Regenhardt D., Rupp O., Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J., Weidner S., Kaiser O., Golyshin P.N. Nat. Biotechnol. 24:997-1004(2006) [PubMed: 16878126] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM286690 Genomic DNA. Translation: CAL16910.1.
RefSeq	YP_693182.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4211821.
GenomeReviews	Gene locus ABO_1462 in contig AM286690_GR.
KEGG	abo:ABO_1462.
NMPDR	fig|393595.12.peg.1468.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0VPI8.
OMA	Q0VPI8. PVIRAIQ.
Enzyme and pathway databases
BioCyc	ABOR393595:ABO_1462-MON.
Family and domain databases
HAMAP	MF_00135. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TRPF_ALCBS

Accession

Primary (citable) accession number: Q0VPI8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 5, 2006
Last modified:	June 16, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)