Reviewed, UniProtKB/Swiss-Prot Q0VPH7 (AROC_ALCBS)

Names and origin

Protein names

Recommended name:
    Chorismate synthase
    EC=4.2.3.5
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	ABO_1473

Organism

Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]

Taxonomic identifier

393595 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Alcanivoracaceae › Alcanivorax

Protein attributes

Sequence length	363 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity. HAMAP MF_00300
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity. HAMAP MF_00300
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 363	363	Chorismate synthase HAMAP MF_00300		PRO_0000256269

Sequences

	Sequence		Length	Mass (Da)
	Q0VPH7-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 373931A67CE04C6A	FASTA	363	38,976
	10 20 30 40 50 60 MAGNSFGERF KITTFGESHG PALGAIVDGC PPGLEISEED LQVELDRRKP GTSRYTTQRR 70 80 90 100 110 120 EPDQVKILSG VFEGKTTGTT IGLLIENTDQ KSKDYSNIAG TFRPGHADYT YTQKYGFRDY 130 140 150 160 170 180 RGGGRSSARE TAMRVAGGAI ARKFLEQRLG IRIYGGCTQI GDVKAESLDW STVNNNPFFF 190 200 210 220 230 240 PDESKVPALE DLINALRKDG SSIGARVEVF ADGVPPGWGE PVFDRIDADL AKAMMSINAV 250 260 270 280 290 300 KGVEIGDGFA VVNQRGEQHR DEMTPQGFLS NHSGGVLGGI SSGQTMRVAM ALKPTSSILI 310 320 330 340 350 360 AGKSIGLNGE AAEVVTKGRH DPCVGVRATP IAEAMLAIVL LDHYLRHRGQ NADVVPPFPP IPG

References

[1]

"Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium Alcanivorax borkumensis." Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M., Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C., Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B., McHardy A.C., Meyer F. , Nechitaylo T., Puehler A., Regenhardt D., Rupp O., Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J., Weidner S., Kaiser O., Golyshin P.N. Nat. Biotechnol. 24:997-1004(2006) [PubMed: 16878126] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM286690 Genomic DNA. Translation: CAL16921.1.
RefSeq	YP_693193.1.
3D structure databases
SMR	Q0VPH7. Positions 4-355.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0VPH7.
Genome annotation databases
GeneID	4213486.
GenomeReviews	Gene locus ABO_1473 in contig AM286690_GR.
KEGG	abo:ABO_1473.
NMPDR	fig|393595.12.peg.1479.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0082.
HOGENOM	HBG292336.
OMA	SRFTTQR.
PhylomeDB	Q0VPH7.
Enzyme and pathway databases
BioCyc	ABOR393595:ABO_1473-MONOMER.
Family and domain databases
HAMAP	MF_00300_B. Chorismate_synth_B. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
TIGRFAMs	TIGR00033. aroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_ALCBS

Accession

Primary (citable) accession number: Q0VPH7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	September 5, 2006
Last modified:	February 9, 2010
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)