Reviewed, UniProtKB/Swiss-Prot Q0VPF7 (SUCC_ALCBS)

Names and origin

Protein names

Recommended name:
    Succinyl-CoA ligase [ADP-forming] subunit beta
    EC=6.2.1.5
Alternative name(s):
    Succinyl-CoA synthetase subunit beta
      Short name=SCS-beta

Gene names

Name:	sucC
Ordered Locus Names:	ABO_1493

Organism

Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]

Taxonomic identifier

393595 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Alcanivoracaceae › Alcanivorax

Protein attributes

Sequence length	389 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + succinate + CoA = ADP + phosphate + succinyl-CoA. HAMAP MF_00558
Cofactor	Binds 1 magnesium or manganese ion per subunit By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle. HAMAP MF_00558
Subunit structure	Heterotetramer of two alpha and two beta subunits By similarity.
Sequence similarities	Belongs to the succinate/malate CoA ligase beta subunit family. Contains 1 ATP-grasp domain.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	ATP-binding Magnesium Manganese Metal-binding Nucleotide-binding
Molecular function	Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW succinate-CoA ligase (ADP-forming) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 389	389	Succinyl-CoA ligase [ADP-forming] subunit beta HAMAP MF_00558		PRO_1000081994
Regions
	Domain	9 – 244	236	ATP-grasp
	Nucleotide binding	35 – 108	74	ATP By similarity
Sites
	Metal binding	197	1	Magnesium or manganese By similarity
	Metal binding	199	1	Magnesium or manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0VPF7-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 1E7F41F62F2B8AA1	FASTA	389	41,402
	10 20 30 40 50 60 MNLHEYQSKQ LFADYGLPVS TGFACDTPEE VAAKAKEIGG DKWVVKAQVH AGGRGKAGGV 70 80 90 100 110 120 KLVDTPEDAA AFAKKWLGKQ LVTFQTDEHG QPVSKILVET CTDIAKELYL SAVLDRASRR 130 140 150 160 170 180 VVFMASTEGG VDIETVAEET PEKILKAEID PLVGAQPYQA REIAFKLGLE GKQVNQFAKI 190 200 210 220 230 240 FVGLAKLFVD KDLALIEVNP LVITDTGDLH CLDAKINVDG SALYRHPDIK ALDDPSQEDE 250 260 270 280 290 300 RERRAAEWDL NYVALEGNIG CMVNGAGLAM GTMDLVKLKG GAPANFLDVG GGATKERVTE 310 320 330 340 350 360 AFKIILSDDQ VKGVLVNIFG GIVRCDLIAE GIIGAVEEVG VTVPVVVRLE GNNAELGSQK 370 380 LAESGMNIIA AQSFDDAAEQ VVKAVGGAA

References

[1]

"Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium Alcanivorax borkumensis." Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M., Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C., Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B., McHardy A.C., Meyer F. , Nechitaylo T., Puehler A., Regenhardt D., Rupp O., Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J., Weidner S., Kaiser O., Golyshin P.N. Nat. Biotechnol. 24:997-1004(2006) [PubMed: 16878126] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM286690 Genomic DNA. Translation: CAL16941.1.
RefSeq	YP_693213.1.
3D structure databases
SMR	Q0VPF7. Positions 1-385.
ModBase	Search...
Genome annotation databases
GeneID	4211974.
GenomeReviews	Gene locus ABO_1493 in contig AM286690_GR.
KEGG	abo:ABO_1493.
NMPDR	fig|393595.12.peg.1500.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0VPF7.
OMA	Q0VPF7. NLHCLDA.
Enzyme and pathway databases
BioCyc	ABOR393595:ABO_1493-MON.
Family and domain databases
HAMAP	MF_00558. [Tree]
InterPro	IPR011761. ATP-grasp. IPR013650. ATP-grasp_succ-CoA_synth-type. IPR013816. ATP_grasp_subdomain_2. IPR005811. CoA_ligase. IPR017866. Succ-CoA_synthase_bsu_CS. IPR005809. Succ_CoA_synthase_bsu. IPR016102. Succinyl-CoA_synth-like. [Graphical view]
Gene3D	G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit. G3DSA:3.40.50.261. Succinyl-CoA_synth-like. 1 hit.
PANTHER	PTHR11815. CoA_lig_beta. 1 hit.
Pfam	PF08442. ATP-grasp_2. 1 hit. PF00549. Ligase_CoA. 1 hit. [Graphical view]
TIGRFAMs	TIGR01016. sucCoAbeta. 1 hit.
PROSITE	PS50975. ATP_GRASP. 1 hit. PS01217. SUCCINYL_COA_LIG_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SUCC_ALCBS

Accession

Primary (citable) accession number: Q0VPF7

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	September 5, 2006
Last modified:	June 16, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)