Reviewed, UniProtKB/Swiss-Prot Q0VP73 (DCD_ALCBS)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	ABO_1577

Organism

Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]

Taxonomic identifier

393595 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Alcanivoracaceae › Alcanivorax

Protein attributes

Sequence length	189 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 189	189	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009675

Sequences

	Sequence		Length	Mass (Da)
	Q0VP73-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 79F1BA013B23E34C	FASTA	189	21,285
	10 20 30 40 50 60 MTIKSDRWIS RMAAEKGMIE PFQPGQVRAD ENGEKLISYG VSSYGYDVRC ADEFKVFTNI 70 80 90 100 110 120 HSATVDPKAF DERSFVDVKG EYCIIPPNSF ALARTVEYFR IPRNVLTICL GKSTYARCGI 130 140 150 160 170 180 IVNVTPLEPE WEGHVTLEFS NTTTLPAKIY AHEGVAQMLF FESDEVCETS YMDRGGKYQG QRGVTLPRA

References

[1]

"Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium Alcanivorax borkumensis." Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M., Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C., Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B., McHardy A.C., Meyer F. , Nechitaylo T., Puehler A., Regenhardt D., Rupp O., Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J., Weidner S., Kaiser O., Golyshin P.N. Nat. Biotechnol. 24:997-1004(2006) [PubMed: 16878126] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM286690 Genomic DNA. Translation: CAL17025.1.
RefSeq	YP_693297.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q0VP73.
Genome annotation databases
GeneID	4213294.
GenomeReviews	Gene locus ABO_1577 in contig AM286690_GR.
KEGG	abo:ABO_1577.
NMPDR	fig|393595.12.peg.1582.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0VP73.
OMA	CAQVLFF.
Enzyme and pathway databases
BioCyc	ABOR393595:ABO_1577-MON.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. [Graphical view]
ProDom	PD004900. dCTP_deaminase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_ALCBS

Accession

Primary (citable) accession number: Q0VP73

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 5, 2006
Last modified:	November 3, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)