Reviewed, UniProtKB/Swiss-Prot Q0VNE1 (SYH_ALCBS)

Names and origin

Protein names

Recommended name:
    Histidyl-tRNA synthetase
    EC=6.1.1.21
Alternative name(s):
    Histidine--tRNA ligase
      Short name=HisRS

Gene names

Name:	hisS
Ordered Locus Names:	ABO_1859

Organism

Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]

Taxonomic identifier

393595 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Alcanivoracaceae › Alcanivorax

Protein attributes

Sequence length	422 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His). HAMAP MF_00127
Subunit structure	Homodimer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP histidine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 422	422	Histidyl-tRNA synthetase HAMAP MF_00127		PRO_1000016307

Sequences

	Sequence		Length	Mass (Da)
	Q0VNE1-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 6A2B20E795997A88	FASTA	422	46,386
	10 20 30 40 50 60 MSKKITSIRG MNDILPEQTG LWQWLEAKVG AVLASYGYQE IRMPIVEQTD LFKRSIGEVT 70 80 90 100 110 120 DIVEKEMYTF DDRNGDSLTL RPEGTASCVR ACEQHGLLYN QTQRLWYAGP MFRHERPQAG 130 140 150 160 170 180 RYRQFHQIGV ETFGMTGPDI DAEVILLTAR LWKALGLEDK VVLELNSLGD SADRARYRDA 190 200 210 220 230 240 LVDYLKAHFD DLDGDSQKRL ERSPLRVLDS KDTGTREVLK GAPQLADYLN DEAVAHFEGL 250 260 270 280 290 300 KALLDASGIA YKVNPYLVRG LDYYGKTVFE WVTDALGAQG TVCAGGRYDG LVEQLGGKPT 310 320 330 340 350 360 PAVGFAMGIE RLILLIEQER PELSAPVDVY VMAMGDVLAP TMALSEHLRD ALPGRAIQLH 370 380 390 400 410 420 CGGGSFKSQM KKADRSGAAV GLIMGEDELA SGVVTVKPLR GQGEQVQVAQ GDVANAVTSF LE

References

[1]

"Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium Alcanivorax borkumensis." Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M., Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C., Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B., McHardy A.C., Meyer F. , Nechitaylo T., Puehler A., Regenhardt D., Rupp O., Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J., Weidner S., Kaiser O., Golyshin P.N. Nat. Biotechnol. 24:997-1004(2006) [PubMed: 16878126] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM286690 Genomic DNA. Translation: CAL17307.1.
RefSeq	YP_693579.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4211474.
GenomeReviews	Gene locus ABO_1859 in contig AM286690_GR.
KEGG	abo:ABO_1859.
NMPDR	fig|393595.12.peg.1864.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0VNE1.
OMA	Q0VNE1. VFEWVTT.
Enzyme and pathway databases
BioCyc	ABOR393595:ABO_1859-MON.
Family and domain databases
HAMAP	MF_00127. [Tree]
InterPro	IPR002314. aa-tRNA-synt_IIb_cons-reg. IPR006195. aa-tRNA-synth_II_cons-reg. IPR004154. Anticodon_bd. IPR015807. His-tRNA-synth_IIa_sub. IPR004516. His-tRNA_synth_IIA. [Graphical view]
Gene3D	G3DSA:3.40.50.800. Anticodon_bd. 1 hit.
PANTHER	PTHR11476. His-tRNA_synth. 1 hit.
Pfam	PF03129. HGTP_anticodon. 1 hit. PF00587. tRNA-synt_2b. 1 hit. [Graphical view]
PIRSF	PIRSF001549. His-tRNA_synth. 1 hit.
TIGRFAMs	TIGR00442. hisS. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYH_ALCBS

Accession

Primary (citable) accession number: Q0VNE1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 5, 2006
Last modified:	June 16, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)