SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q0VMK6

- GCH4_ALCBS

UniProt

Q0VMK6 - GCH4_ALCBS

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

GTP cyclohydrolase FolE2

Gene
folE2, ABO_2144
Organism
Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Converts GTP to 7,8-dihydroneopterin triphosphate By similarity.UniRule annotation

Catalytic activityi

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei152 – 1521May be catalytically important By similarity

GO - Molecular functioni

  1. GTP cyclohydrolase I activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 7,8-dihydroneopterin 3'-triphosphate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciABOR393595:GHRI-2192-MONOMER.
UniPathwayiUPA00848; UER00151.

Names & Taxonomyi

Protein namesi
Recommended name:
GTP cyclohydrolase FolE2 (EC:3.5.4.16)
Gene namesi
Name:folE2
Ordered Locus Names:ABO_2144
OrganismiAlcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
Taxonomic identifieri393595 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesAlcanivoracaceaeAlcanivorax
ProteomesiUP000008871: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 307307GTP cyclohydrolase FolE2UniRule annotationPRO_0000289471Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi393595.ABO_2144.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1469.
HOGENOMiHOG000247517.
KOiK09007.
OrthoDBiEOG6X6RBH.

Family and domain databases

HAMAPiMF_01527_B. GTP_cyclohydrol_B.
InterProiIPR022838. GTP_cyclohydrolase_FolE2.
IPR003801. GTP_cyclohydrolase_FolE2/MptA.
[Graphical view]
PfamiPF02649. GCHY-1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0VMK6-1 [UniParc]FASTAAdd to Basket

« Hide

MPDVASNSMV DHIHTTLDWV GMSEIHLPAR VSDTLAGERP VSTSIQAYVN    50
LANADAKGIH MSRLFLMLEE TFGDHSVSAG SIEQLLRNFL QTHEGLSTRG 100
FVQLDFEYSM RRAALKSSYS GWKSYPVSIK GTLCEDGMRI ELSVEVPYSS 150
TCPCSAALSR QLIQEQFRKD FEESKVDTDA VLEWLGTEEG ILATPHSQRS 200
IAQVRVLLDH NVGDAFPITA LIDSIEGALK TPVQTAVKRV DEQEFALLNG 250
QNLMFCEDAA RRLKTALNPQ SCYKDFWLRV NHLESLHAHN AVAIVTKEVE 300
GGYLPIP 307
Length:307
Mass (Da):34,092
Last modified:May 5, 2009 - v2
Checksum:i1ABDF62C95C34D2D
GO

Sequence cautioni

The sequence CAL17592.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM286690 Genomic DNA. Translation: CAL17592.1. Different initiation.
RefSeqiYP_693864.1. NC_008260.1.

Genome annotation databases

EnsemblBacteriaiCAL17592; CAL17592; ABO_2144.
GeneIDi4212070.
KEGGiabo:ABO_2144.
PATRICi20842149. VBIAlcBor124741_2244.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM286690 Genomic DNA. Translation: CAL17592.1 . Different initiation.
RefSeqi YP_693864.1. NC_008260.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 393595.ABO_2144.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAL17592 ; CAL17592 ; ABO_2144 .
GeneIDi 4212070.
KEGGi abo:ABO_2144.
PATRICi 20842149. VBIAlcBor124741_2244.

Phylogenomic databases

eggNOGi COG1469.
HOGENOMi HOG000247517.
KOi K09007.
OrthoDBi EOG6X6RBH.

Enzyme and pathway databases

UniPathwayi UPA00848 ; UER00151 .
BioCyci ABOR393595:GHRI-2192-MONOMER.

Family and domain databases

HAMAPi MF_01527_B. GTP_cyclohydrol_B.
InterProi IPR022838. GTP_cyclohydrolase_FolE2.
IPR003801. GTP_cyclohydrolase_FolE2/MptA.
[Graphical view ]
Pfami PF02649. GCHY-1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SK2 / ATCC 700651 / DSM 11573.

Entry informationi

Entry nameiGCH4_ALCBS
AccessioniPrimary (citable) accession number: Q0VMK6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 5, 2009
Last modified: May 14, 2014
This is version 50 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi