Reviewed, UniProtKB/Swiss-Prot Q0VMD7 (PSD_ALCBS)

Names and origin

Protein names

Recommended name:
    Phosphatidylserine decarboxylase proenzyme
    EC=4.1.1.65
Cleaved into the following 2 chains:
    1- Recommended name:
            Phosphatidylserine decarboxylase alpha chain
    2- Recommended name:
            Phosphatidylserine decarboxylase beta chain

Gene names

Name:	psd
Ordered Locus Names:	ABO_2213

Organism

Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]

Taxonomic identifier

393595 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Alcanivoracaceae › Alcanivorax

Protein attributes

Sequence length	291 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662
Cofactor	Pyruvoyl group By similarity. HAMAP MF_00662
Pathway	Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662
Sequence similarities	Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
PTM	Zymogen
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phospholipid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 252	252	Phosphatidylserine decarboxylase beta chain By similarity		PRO_0000262089
	Chain	253 – 291	39	Phosphatidylserine decarboxylase alpha chain By similarity		PRO_0000262090
Sites
	Site	252 – 253	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	253	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0VMD7-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 1B32816A56727AA0	FASTA	291	32,065
	10 20 30 40 50 60 MSLRDKLFVT LQYLIPQHAL SRLVGILARS EVPWIKTTFI NMFMKRFGID LSEAQIEDAD 70 80 90 100 110 120 QFPTFNAFFT RALKADARPL EASESNDIAS PADGAVSQLG AIRANQVFQA KGHDYSLYDL 130 140 150 160 170 180 LGGDSALASE FTNGQFATVY LSPRDYHRVH MPFTGTLRET RYVPGDLFSV NEATANGVPN 190 200 210 220 230 240 LFARNERLVC IFDTEQGPMA VILVGAMIVA GIETVFSGQV TPLPKQVVTT DYLRSKPIAL 250 260 270 280 290 EKGEELGRFL LGSTVVMLFP EGKAKFAPNL KPGSQVRVRG KLGAYTNENK H

References

[1]

"Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium Alcanivorax borkumensis." Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M., Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C., Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B., McHardy A.C., Meyer F. , Nechitaylo T., Puehler A., Regenhardt D., Rupp O., Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J., Weidner S., Kaiser O., Golyshin P.N. Nat. Biotechnol. 24:997-1004(2006) [PubMed: 16878126] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM286690 Genomic DNA. Translation: CAL17661.1.
RefSeq	YP_693933.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q0VMD7.
Genome annotation databases
GeneID	4211226.
GenomeReviews	Gene locus ABO_2213 in contig AM286690_GR.
KEGG	abo:ABO_2213.
NMPDR	fig|393595.12.peg.2212.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0688.
HOGENOM	HBG302256.
OMA	YVPGRLF.
PhylomeDB	Q0VMD7.
Enzyme and pathway databases
BioCyc	ABOR393595:ABO_2213-MONOMER.
Family and domain databases
HAMAP	MF_00662. PS_decarb_type1. [Tree]
InterPro	IPR003817. PS_Dcarbxylase. IPR005221. PS_decarb. [Graphical view]
PANTHER	PTHR10067. PS_decarb. 1 hit.
Pfam	PF02666. PS_Dcarbxylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00163. PS_decarb. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PSD_ALCBS

Accession

Primary (citable) accession number: Q0VMD7

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	September 5, 2006
Last modified:	February 9, 2010
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)