Reviewed, UniProtKB/Swiss-Prot Q0VMA8 (SYR_ALCBS)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	ABO_2242

Organism

Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]

Taxonomic identifier

393595 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Alcanivoracaceae › Alcanivorax

Protein attributes

Sequence length	584 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity. HAMAP MF_00123
Subcellular location	Cytoplasm HAMAP MF_00123.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 584	584	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_1000017983
Regions
	Motif	127 – 137	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q0VMA8-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 149D458D7B2E61F5	FASTA	584	64,882
	10 20 30 40 50 60 MKERLISLIE SALDTLITDG TLPADAKRPV QIDRTRDKSH GDFATNIALM LAKPAGMKPR 70 80 90 100 110 120 DLAEKLIAAL PNDSAVAKVD IAGPGFINFF QADDWLTGLL DSALADDFLG ISRPEQPQTV 130 140 150 160 170 180 VVDYSSPNLA KEMHVGHLRS TIIGDAVVRT LEFLGHTVIR QNHVGDWGTQ FGMLLAYLEE 190 200 210 220 230 240 QKTEEGEREL SRELANLETF YRAAKQRFDE SDSFADRARA LVVKLQSGDD YCLTLWAEFN 250 260 270 280 290 300 QVSLSHCQAI YDRLGVSLTP ADVHGESAYN DDLAQVVADL DSKGLLSESQ GAQCVFMDAF 310 320 330 340 350 360 KNKEGEPLPV IVRKADGGYL YATSDLAALR YRASTLRADR MLYFVDQRQA LHFQQMFTLA 370 380 390 400 410 420 KLAGFVPEQT ELAHMGFGTM NGPDGRPFKT RDGGTVKLVD LLDEAEQRAF ALVQEKNPQL 430 440 450 460 470 480 DDEELRNIAR SVGIGAVKYA DLSKNRSSDY IFNFEQMLSF EGNTAPYLLY AYTRVASVFR 490 500 510 520 530 540 KAELDMANVS GDFLLNEDAE HTLAARLVQF GEVLQNVADK GQPHLLSAYL YDVAGLFSSF 550 560 570 580 YEHCPILSSE DERIRQSRLK LAALTARTLK HGMELLGLSP LERM

References

[1]

"Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium Alcanivorax borkumensis." Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M., Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C., Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B., McHardy A.C., Meyer F. , Nechitaylo T., Puehler A., Regenhardt D., Rupp O., Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J., Weidner S., Kaiser O., Golyshin P.N. Nat. Biotechnol. 24:997-1004(2006) [PubMed: 16878126] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM286690 Genomic DNA. Translation: CAL17690.1.
RefSeq	YP_693962.1.
3D structure databases
SMR	Q0VMA8. Positions 1-584.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0VMA8.
Genome annotation databases
GeneID	4213484.
GenomeReviews	Gene locus ABO_2242 in contig AM286690_GR.
KEGG	abo:ABO_2242.
NMPDR	fig|393595.12.peg.2242.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0018.
HOGENOM	HBG695395.
OMA	HMGFGTM.
PhylomeDB	Q0VMA8.
Enzyme and pathway databases
BioCyc	ABOR393595:ABO_2242-MONOMER.
Family and domain databases
HAMAP	MF_00123. Arg_tRNA_synth. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
Gene3D	G3DSA:3.30.1360.70. Arg-tRNA-synth_Ic_N. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM00836. DALR_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_ALCBS

Accession

Primary (citable) accession number: Q0VMA8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 5, 2006
Last modified:	February 9, 2010
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)