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Reviewed, UniProtKB/Swiss-Prot Q0VLC7 (TRMB_ALCBS)

Last modified June 16, 2009. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    tRNA (guanine-N(7)-)-methyltransferase
    EC=2.1.1.33
Alternative name(s):
    tRNA(m7G46)-methyltransferase
Gene names
Name: trmB
Ordered Locus Names: ABO_2573
OrganismAlcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) [Complete proteome] [HAMAP]
Taxonomic identifier393595 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Alcanivoracaceae › Alcanivorax

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Protein attributes

Sequence length239 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.

Catalytic activity

S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N(7)-methylguanine. HAMAP MF_01057

Pathway

tRNA modification; N(7)-methylguanine-tRNA biosynthesis. HAMAP MF_01057

Sequence similarities

Belongs to the methyltransferase superfamily. TrmB family.

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Ontologies

Keywords
   Biological processtRNA processing
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtRNA modification

Inferred from electronic annotation. Source: HAMAP

   Molecular functiontRNA (guanine-N7-)-methyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 239239tRNA (guanine-N(7)-)-methyltransferase HAMAP MF_01057
PRO_0000288115

Regions

Region217 – 2204Substrate binding Potential

Sites

Binding site691S-adenosyl-L-methionine By similarity
Binding site941S-adenosyl-L-methionine By similarity
Binding site1211S-adenosyl-L-methionine By similarity
Binding site1441S-adenosyl-L-methionine By similarity
Binding site1481Substrate By similarity
Binding site1801Substrate Potential

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Sequences

Sequence LengthMass (Da)Tools
Q0VLC7-1 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 83740B9F34ED94AC

FASTA23927,171
        10         20         30         40         50         60 
MLDFINHDKD PETGKVMRKV RSFVLREGRL TAGQRNALDT LWPRFGLERD QGMLNPESVF 

        70         80         90        100        110        120 
GRDAPRVLEI GYGMGQSLAQ MAAADPDKDF IGIEVHRPGV GALLMEIEQQ GLSNLRSYCD 

       130        140        150        160        170        180 
DAVEILELCI PDNSLARVQL YFPDPWHKKK HHKRRIVQPA WVALVQRKLQ PGGILHMATD 

       190        200        210        220        230 
WENYAEHMME VMDAAAGFSN LAGPSAFSPR PSWRPETKFE RRGEKLGHGV WDLLFEKRA

« Hide

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Cross-references

Sequence databases

AM286690 Genomic DNA. Translation: CAL18021.1.
RefSeqYP_694293.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID4213307.
GenomeReviewsGene locus ABO_2573 in contig AM286690_GR.
KEGGabo:ABO_2573.
NMPDRfig|393595.12.peg.2580.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ0VLC7.
OMAQ0VLC7. TKFENRG.

Enzyme and pathway databases

BioCycABOR393595:ABO_2573-MON.

Family and domain databases

HAMAPMF_01057.
[Tree]
InterProIPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PANTHERPTHR23417:SF1. Methyltransf_4. 1 hit.
PfamPF02390. Methyltransf_4. 1 hit.
[Graphical view]
TIGRFAMsTIGR00091. CHP91. 1 hit.
ProtoNetSearch...

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Entry information

Entry nameTRMB_ALCBS
AccessionPrimary (citable) accession number: Q0VLC7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: September 5, 2006
Last modified: June 16, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents