Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q0VLA8

- GCSPA_ALCBS

UniProt

Q0VLA8 - GCSPA_ALCBS

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable glycine dehydrogenase (decarboxylating) subunit 1

Gene

gcvPA

Organism
Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.UniRule annotation

Catalytic activityi

Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2.UniRule annotation

GO - Molecular functioni

  1. glycine dehydrogenase (decarboxylating) activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glycine catabolic process Source: InterPro
  2. nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciABOR393595:GHRI-2643-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glycine dehydrogenase (decarboxylating) subunit 1UniRule annotation (EC:1.4.4.2UniRule annotation)
Alternative name(s):
Glycine cleavage system P-protein subunit 1UniRule annotation
Glycine decarboxylase subunit 1UniRule annotation
Glycine dehydrogenase (aminomethyl-transferring) subunit 1UniRule annotation
Gene namesi
Name:gcvPAUniRule annotation
Ordered Locus Names:ABO_2592
OrganismiAlcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
Taxonomic identifieri393595 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesAlcanivoracaceaeAlcanivorax
ProteomesiUP000008871: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 452452Probable glycine dehydrogenase (decarboxylating) subunit 1PRO_1000045634Add
BLAST

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.UniRule annotation

Protein-protein interaction databases

STRINGi393595.ABO_2592.

Structurei

3D structure databases

ProteinModelPortaliQ0VLA8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvP family. N-terminal subunit subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0403.
HOGENOMiHOG000132025.
KOiK00282.
OMAiFFHEAVL.
OrthoDBiEOG6XWV3B.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
HAMAPiMF_00712. GcvPA.
InterProiIPR023010. GcvPA.
IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11773. PTHR11773. 1 hit.
PfamiPF02347. GDC-P. 1 hit.
[Graphical view]
PIRSFiPIRSF006815. GcvPA. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0VLA8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPYIPHTPDD VRAMLDAIGA DSIEDLFDEI PSHLKAAGKL DALPEGLSEM
60 70 80 90 100
DVTRLMSDRA AQDAGAVSFI GAGAYQHHVP AAVWEIATRG EFYTAYTPYQ
110 120 130 140 150
AEASQGTLQV IYEFQTLMTR LTGMDVSNAS VYDGASGLAE AVLMSLRANR
160 170 180 190 200
KSKSRKVLVP TAVNPRYTSA TQAIVENQDV ALERVGFDAA SGQTPLDALK
210 220 230 240 250
PYEGEDYAAL VISQPNFFGS LEEVDALTDW AHANKMLVIG VVNPTSLALL
260 270 280 290 300
TPPGEWGADG ADIVVGEGQP LGVPLSSGGP YFGFMCCKQK HVRQMPGRII
310 320 330 340 350
GRTVDMEGKQ GFTLTLQARE QHIRRSKATS NICTNQGLAM TAATIYTSLL
360 370 380 390 400
GPDGLGNVAA HCHANTQALA DKLTAIDGVE RAFTAPTFHE VVLTLPKPAD
410 420 430 440 450
QVLAALAEKD VLGGVSLAGD YDMNNAILVN ATEVHSEQDL QLFEQALKEV

LA
Length:452
Mass (Da):48,258
Last modified:September 5, 2006 - v1
Checksum:iC06CE02A24606C06
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286690 Genomic DNA. Translation: CAL18040.1.
RefSeqiYP_694312.1. NC_008260.1.

Genome annotation databases

EnsemblBacteriaiCAL18040; CAL18040; ABO_2592.
GeneIDi4211691.
KEGGiabo:ABO_2592.
PATRICi20843077. VBIAlcBor124741_2705.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286690 Genomic DNA. Translation: CAL18040.1 .
RefSeqi YP_694312.1. NC_008260.1.

3D structure databases

ProteinModelPortali Q0VLA8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 393595.ABO_2592.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAL18040 ; CAL18040 ; ABO_2592 .
GeneIDi 4211691.
KEGGi abo:ABO_2592.
PATRICi 20843077. VBIAlcBor124741_2705.

Phylogenomic databases

eggNOGi COG0403.
HOGENOMi HOG000132025.
KOi K00282.
OMAi FFHEAVL.
OrthoDBi EOG6XWV3B.

Enzyme and pathway databases

BioCyci ABOR393595:GHRI-2643-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
HAMAPi MF_00712. GcvPA.
InterProi IPR023010. GcvPA.
IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11773. PTHR11773. 1 hit.
Pfami PF02347. GDC-P. 1 hit.
[Graphical view ]
PIRSFi PIRSF006815. GcvPA. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SK2 / ATCC 700651 / DSM 11573.

Entry informationi

Entry nameiGCSPA_ALCBS
AccessioniPrimary (citable) accession number: Q0VLA8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 5, 2006
Last modified: November 26, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3