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Protein

Glycerate kinase

Gene

Glyctk

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + D-glycerate = ADP + 3-phospho-D-glycerate.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-RNO-70350 Fructose catabolism
SABIO-RKQ0VGK3

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerate kinase (EC:2.7.1.31)
Gene namesi
Name:Glyctk
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi1591498 Glyctk

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002871951 – 523Glycerate kinaseAdd BLAST523

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei60PhosphoserineCombined sources1
Modified residuei200N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ0VGK3
PRIDEiQ0VGK3

PTM databases

iPTMnetiQ0VGK3
PhosphoSitePlusiQ0VGK3

Expressioni

Gene expression databases

BgeeiENSRNOG00000046307
GenevisibleiQ0VGK3 RN

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064339

Structurei

3D structure databases

ProteinModelPortaliQ0VGK3
SMRiQ0VGK3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi94 – 97Poly-Ala4

Sequence similaritiesi

Belongs to the glycerate kinase type-2 family.Curated

Phylogenomic databases

eggNOGiKOG3935 Eukaryota
COG2379 LUCA
GeneTreeiENSGT00390000014365
HOVERGENiHBG098351
InParanoidiQ0VGK3
KOiK11529
OMAiHTGTNVM
OrthoDBiEOG091G0HT4
PhylomeDBiQ0VGK3

Family and domain databases

Gene3Di3.40.50.10180, 1 hit
InterProiView protein in InterPro
IPR038614 GK_N_sf
IPR007835 MOFRL
IPR025286 MOFRL_assoc_dom
PfamiView protein in Pfam
PF13660 DUF4147, 1 hit
PF05161 MOFRL, 1 hit

Sequencei

Sequence statusi: Complete.

Q0VGK3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAALQVLPC LLRAPSRPFL WGPPVARMTS GMALAEQARQ LFDSAVGAVQ
60 70 80 90 100
PGPMLQRTLS LDPSGKQLKV RDRTFQLQEN LYLVGFGKAV LGMAAAADEL
110 120 130 140 150
LGQHLVQGVI SVPKGIRAAV ELAGKQEMLL KPHSHIQVFE GAEDNLPDRD
160 170 180 190 200
ALRAAQAIQQ LAERLTADDL LLVLISGGGS ALLPAPIPPV TLEEKQTLTK
210 220 230 240 250
LLAARGATIQ ELNTIRKALS QLKGGGLAQA AYPAQVVSLI LSDVIGDPLE
260 270 280 290 300
VIASGPTVAS THSVQDCLHI LNHYGLRAAL PRSVKTVLSR ADSDPHGPHT
310 320 330 340 350
CGHVLNVIIG SNSLALAEAQ RQAEVLGYHA MVLSTAMQGD VRRVAQFYGL
360 370 380 390 400
LARVAAACLT SSTAERPLEE EAKLHQLAAE LQLPDLQLEE ALEAVAKAKG
410 420 430 440 450
PVCLLAGGEP TVQLQGSGKG GRNQELALRV GAELGKQPLG PVDVLFLSGG
460 470 480 490 500
TDGQDGPTKV AGAWVMSDLV SQASAENLDF ATFLDNNDSY TFFCSFQGGT
510 520
HLLHTGLTGT NVMDVHLLVF HPQ
Length:523
Mass (Da):55,187
Last modified:September 5, 2006 - v1
Checksum:iE6E4E2F009A98243
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC105621 mRNA Translation: AAI05622.1
RefSeqiNP_001102919.1, NM_001109449.2
XP_006243918.1, XM_006243856.3
XP_006243919.1, XM_006243857.3
UniGeneiRn.202605

Genome annotation databases

EnsembliENSRNOT00000074595; ENSRNOP00000064339; ENSRNOG00000046307
GeneIDi684314
KEGGirno:684314

Similar proteinsi

Entry informationi

Entry nameiGLCTK_RAT
AccessioniPrimary (citable) accession number: Q0VGK3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: September 5, 2006
Last modified: May 23, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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