Reviewed, UniProtKB/Swiss-Prot Q0VGK3 (GLCTK_RAT)

Names and origin

Protein names

Recommended name:
    Glycerate kinase
    EC=2.7.1.31

Gene names

Name:

Glyctk

Organism

Rattus norvegicus (Rat)

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	523 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	ATP + (R)-glycerate = ADP + 3-phospho-(R)-glycerate.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the glycerate kinase type-2 family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Gene Ontology (GO)
Biological process	protein amino acid phosphorylation Inferred from sequence or structural similarity. Source: UniProtKB
Cellular component	cytoplasm Inferred from sequence or structural similarity. Source: UniProtKB
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glycerate kinase activity Inferred from sequence or structural similarity. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 523	523	Glycerate kinase		PRO_0000287195
Regions
	Compositional bias	94 – 97	4	Poly-Ala

Sequences

	Sequence		Length	Mass (Da)
	Q0VGK3-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: E6E4E2F009A98243	FASTA	523	55,187
	10 20 30 40 50 60 MAAALQVLPC LLRAPSRPFL WGPPVARMTS GMALAEQARQ LFDSAVGAVQ PGPMLQRTLS 70 80 90 100 110 120 LDPSGKQLKV RDRTFQLQEN LYLVGFGKAV LGMAAAADEL LGQHLVQGVI SVPKGIRAAV 130 140 150 160 170 180 ELAGKQEMLL KPHSHIQVFE GAEDNLPDRD ALRAAQAIQQ LAERLTADDL LLVLISGGGS 190 200 210 220 230 240 ALLPAPIPPV TLEEKQTLTK LLAARGATIQ ELNTIRKALS QLKGGGLAQA AYPAQVVSLI 250 260 270 280 290 300 LSDVIGDPLE VIASGPTVAS THSVQDCLHI LNHYGLRAAL PRSVKTVLSR ADSDPHGPHT 310 320 330 340 350 360 CGHVLNVIIG SNSLALAEAQ RQAEVLGYHA MVLSTAMQGD VRRVAQFYGL LARVAAACLT 370 380 390 400 410 420 SSTAERPLEE EAKLHQLAAE LQLPDLQLEE ALEAVAKAKG PVCLLAGGEP TVQLQGSGKG 430 440 450 460 470 480 GRNQELALRV GAELGKQPLG PVDVLFLSGG TDGQDGPTKV AGAWVMSDLV SQASAENLDF 490 500 510 520 ATFLDNNDSY TFFCSFQGGT HLLHTGLTGT NVMDVHLLVF HPQ

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC105621 mRNA. Translation: AAI05622.1.
IPI	IPI00766037.
RefSeq	NP_001102919.1.
UniGene	Rn.202605
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	684314.
KEGG	rno:684314.
Organism-specific databases
RGD	1591498. LOC684314.
Phylogenomic databases
HOVERGEN	Q0VGK3.
Enzyme and pathway databases
BRENDA	2.7.1.31. 248.
Family and domain databases
InterPro	IPR007835. MOFRL. [Graphical view]
Pfam	PF05161. MOFRL. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	727142.

Entry information

Entry name

GLCTK_RAT

Accession

Primary (citable) accession number: Q0VGK3

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 15, 2007
Last sequence update:	September 5, 2006
Last modified:	June 16, 2009
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)