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Protein

Glycerate kinase

Gene

Glyctk

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + D-glycerate = ADP + 3-phospho-D-glycerate.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-RNO-70350. Fructose catabolism.
SABIO-RKQ0VGK3.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerate kinase (EC:2.7.1.31)
Gene namesi
Name:Glyctk
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi1591498. Glyctk.

Subcellular locationi

  • Cytoplasm By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002871951 – 523Glycerate kinaseAdd BLAST523

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei60PhosphoserineCombined sources1
Modified residuei200N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ0VGK3.
PRIDEiQ0VGK3.

PTM databases

iPTMnetiQ0VGK3.
PhosphoSitePlusiQ0VGK3.

Expressioni

Gene expression databases

BgeeiENSRNOG00000046307.
GenevisibleiQ0VGK3. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064339.

Structurei

3D structure databases

ProteinModelPortaliQ0VGK3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi94 – 97Poly-Ala4

Sequence similaritiesi

Belongs to the glycerate kinase type-2 family.Curated

Phylogenomic databases

eggNOGiKOG3935. Eukaryota.
COG2379. LUCA.
GeneTreeiENSGT00390000014365.
HOVERGENiHBG098351.
InParanoidiQ0VGK3.
KOiK11529.
OMAiTHTNVND.
OrthoDBiEOG091G0HT4.
PhylomeDBiQ0VGK3.

Family and domain databases

Gene3Di3.40.1480.10. 2 hits.
InterProiIPR007835. MOFRL.
IPR025286. MOFRL_assoc_dom.
[Graphical view]
PfamiPF13660. DUF4147. 1 hit.
PF05161. MOFRL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0VGK3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAALQVLPC LLRAPSRPFL WGPPVARMTS GMALAEQARQ LFDSAVGAVQ
60 70 80 90 100
PGPMLQRTLS LDPSGKQLKV RDRTFQLQEN LYLVGFGKAV LGMAAAADEL
110 120 130 140 150
LGQHLVQGVI SVPKGIRAAV ELAGKQEMLL KPHSHIQVFE GAEDNLPDRD
160 170 180 190 200
ALRAAQAIQQ LAERLTADDL LLVLISGGGS ALLPAPIPPV TLEEKQTLTK
210 220 230 240 250
LLAARGATIQ ELNTIRKALS QLKGGGLAQA AYPAQVVSLI LSDVIGDPLE
260 270 280 290 300
VIASGPTVAS THSVQDCLHI LNHYGLRAAL PRSVKTVLSR ADSDPHGPHT
310 320 330 340 350
CGHVLNVIIG SNSLALAEAQ RQAEVLGYHA MVLSTAMQGD VRRVAQFYGL
360 370 380 390 400
LARVAAACLT SSTAERPLEE EAKLHQLAAE LQLPDLQLEE ALEAVAKAKG
410 420 430 440 450
PVCLLAGGEP TVQLQGSGKG GRNQELALRV GAELGKQPLG PVDVLFLSGG
460 470 480 490 500
TDGQDGPTKV AGAWVMSDLV SQASAENLDF ATFLDNNDSY TFFCSFQGGT
510 520
HLLHTGLTGT NVMDVHLLVF HPQ
Length:523
Mass (Da):55,187
Last modified:September 5, 2006 - v1
Checksum:iE6E4E2F009A98243
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC105621 mRNA. Translation: AAI05622.1.
RefSeqiNP_001102919.1. NM_001109449.2.
XP_006243918.1. XM_006243856.3.
XP_006243919.1. XM_006243857.3.
UniGeneiRn.202605.

Genome annotation databases

EnsembliENSRNOT00000074595; ENSRNOP00000064339; ENSRNOG00000046307.
GeneIDi684314.
KEGGirno:684314.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC105621 mRNA. Translation: AAI05622.1.
RefSeqiNP_001102919.1. NM_001109449.2.
XP_006243918.1. XM_006243856.3.
XP_006243919.1. XM_006243857.3.
UniGeneiRn.202605.

3D structure databases

ProteinModelPortaliQ0VGK3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064339.

PTM databases

iPTMnetiQ0VGK3.
PhosphoSitePlusiQ0VGK3.

Proteomic databases

PaxDbiQ0VGK3.
PRIDEiQ0VGK3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000074595; ENSRNOP00000064339; ENSRNOG00000046307.
GeneIDi684314.
KEGGirno:684314.

Organism-specific databases

CTDi132158.
RGDi1591498. Glyctk.

Phylogenomic databases

eggNOGiKOG3935. Eukaryota.
COG2379. LUCA.
GeneTreeiENSGT00390000014365.
HOVERGENiHBG098351.
InParanoidiQ0VGK3.
KOiK11529.
OMAiTHTNVND.
OrthoDBiEOG091G0HT4.
PhylomeDBiQ0VGK3.

Enzyme and pathway databases

ReactomeiR-RNO-70350. Fructose catabolism.
SABIO-RKQ0VGK3.

Miscellaneous databases

PROiQ0VGK3.

Gene expression databases

BgeeiENSRNOG00000046307.
GenevisibleiQ0VGK3. RN.

Family and domain databases

Gene3Di3.40.1480.10. 2 hits.
InterProiIPR007835. MOFRL.
IPR025286. MOFRL_assoc_dom.
[Graphical view]
PfamiPF13660. DUF4147. 1 hit.
PF05161. MOFRL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLCTK_RAT
AccessioniPrimary (citable) accession number: Q0VGK3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: September 5, 2006
Last modified: November 2, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.