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Protein
Submitted name:

Synaptic nuclear envelope 1

Gene

Syne1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Synaptic nuclear envelope 1Imported
Gene namesi
Name:Syne1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1927152. Syne1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 898CytoplasmicPROSITE-ProRule annotationAdd BLAST898
Transmembranei892 – 917HelicalSequence analysisAdd BLAST26
Topological domaini920 – 949Perinuclear spacePROSITE-ProRule annotationAdd BLAST30

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ0VGB8.
PeptideAtlasiQ0VGB8.
PRIDEiQ0VGB8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000096054.
ExpressionAtlasiQ0VGB8. baseline and differential.
GenevisibleiQ0VGB8. MM.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ0VGB8.
SMRiQ0VGB8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini890 – 949KASHInterPro annotationAdd BLAST60

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IUP1. Eukaryota.
ENOG410YQV5. LUCA.
HOGENOMiHOG000120125.
HOVERGENiHBG056327.

Family and domain databases

InterProiView protein in InterPro
IPR012315. KASH.
IPR018159. Spectrin/alpha-actinin.
IPR002017. Spectrin_repeat.
IPR030265. SYNE1.
PANTHERiPTHR11915:SF362. PTHR11915:SF362. 1 hit.
PfamiView protein in Pfam
PF10541. KASH. 1 hit.
PF00435. Spectrin. 4 hits.
SMARTiView protein in SMART
SM01249. KASH. 1 hit.
SM00150. SPEC. 5 hits.
PROSITEiView protein in PROSITE
PS51049. KASH. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0VGB8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVAEDLHGP RMAEDSSVDA DLPDCDCDVS RVKKLKETLV AVQQLDKNMG
60 70 80 90 100
SLRTWLAHME SELAKPIVYD SCNSEEIQRK LNEQQELQRD IEKHSTGVAS
110 120 130 140 150
VLNLCEVLLH DCDACATDAE CDSIQQATRN LDRRWRNICA MSMERRLKIE
160 170 180 190 200
ETWRLWQKFL DDYSRFEDWL EVSERTAAFP SSSGVLYTVA KEELKKFEAF
210 220 230 240 250
QRQVHESLTQ LELINKQYRR LARENRTDSA CSLRQMVHGG NQRWDDLQKR
260 270 280 290 300
VTSILRRLKH FISQREEFET ARDSILVWLT EMDLQLTNIE HFSECDVQAK
310 320 330 340 350
IKQLKAFQQE ISLNHNKIEQ IIAQGEQLIE KSEPLDAAVI EEELDELRRY
360 370 380 390 400
CQEVFGRVER YHKKLIRLPL PDDHDLSDRE LDLEDSTALS DLRWQDPSAD
410 420 430 440 450
GMPSPQPSSN PSLSLPQPLR SERSGRDTPA SVDSIPLEWD HDYDLSRDLE
460 470 480 490 500
SASRTLPSED EEGEEDKEFY LRGAVGLSGD PSSLESQMRQ LDKALDDSRF
510 520 530 540 550
QIQQTANILR SKTPTGPDLD TSYKGYMKLL GECSGSIDSV RRLEHKLAEE
560 570 580 590 600
ESFPGFVNLN STETQTAGVI DRWELLQAQA MSKELRMKQN LQKWQQFNSD
610 620 630 640 650
LNNIWAWLGE TEEELDRLQH LALSTDIHTI ESHIKKLKEL QKAVDHRKAI
660 670 680 690 700
ILSINLCSSE FTQADSKESH DLQDRLSQMN GRWDRVCSLL EDWRGLLQDA
710 720 730 740 750
LMQCQEFHEM SHALLLMLEN IDRRKNEIVP IDSTLDPETL QDHHKQLMQI
760 770 780 790 800
KQELLKSQLR VASLQDMSRQ LLVNAEGSDC LEAKEKVHVI GNRLKLLLKE
810 820 830 840 850
VSHHIKDLEK LLDMSSSQQD LSSWSSADEL DTSGSVSPTS GRSTPNRQKS
860 870 880 890 900
PRGKCSLSQP GPSVSSPKSR STRDGSDSSR SDPRPERVGR AFLFRILRAA
910 920 930 940
LPFQLLLLLL IGLTCLVPMS EKDYSCALSN NFARSFHPML RYTNGPPPL
Length:949
Mass (Da):108,779
Last modified:September 5, 2006 - v1
Checksum:i40ABE338F614825E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC110428 mRNA. Translation: AAI10429.1.
RefSeqiNP_071310.2. NM_022027.2.
UniGeneiMm.331626.

Genome annotation databases

GeneIDi64009.
UCSCiuc007egr.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ0VGB8_MOUSE
AccessioniPrimary (citable) accession number: Q0VGB8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: August 30, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)