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Protein

Palmitoyltransferase

Gene

Zdhhc17

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionAcyltransferaseUniRule annotationSAAS annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:Zdhhc17Imported
ORF Names:mCG_122237Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2445110. Zdhhc17.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei295 – 311HelicalUniRule annotationAdd BLAST17
Transmembranei317 – 335HelicalUniRule annotationAdd BLAST19
Transmembranei347 – 369HelicalUniRule annotationAdd BLAST23
Transmembranei375 – 393HelicalUniRule annotationAdd BLAST19
Transmembranei475 – 496HelicalUniRule annotationAdd BLAST22
Transmembranei529 – 551HelicalUniRule annotationAdd BLAST23

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiQ0VFY6.

Expressioni

Gene expression databases

BgeeiENSMUSG00000035798.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000043279.

Structurei

3D structure databases

ProteinModelPortaliQ0VFY6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 267ANK_REP_REGIONInterPro annotationAdd BLAST214
Repeati79 – 111ANKPROSITE-ProRule annotationAdd BLAST33
Repeati113 – 145ANKPROSITE-ProRule annotationAdd BLAST33
Repeati146 – 178ANKPROSITE-ProRule annotationAdd BLAST33
Repeati179 – 212ANKPROSITE-ProRule annotationAdd BLAST34
Repeati214 – 246ANKPROSITE-ProRule annotationAdd BLAST33

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotationSAAS annotation

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0509. Eukaryota.
COG0666. LUCA.
COG5273. LUCA.
HOVERGENiHBG051907.

Family and domain databases

Gene3Di1.25.40.20. 2 hits.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR001594. Palmitoyltrfase_DHHC.
IPR030289. ZDHHC17.
PANTHERiPTHR24161:SF39. PTHR24161:SF39. 1 hit.
PfamiView protein in Pfam
PF12796. Ank_2. 2 hits.
PF01529. zf-DHHC. 1 hit.
PRINTSiPR01415. ANKYRIN.
SMARTiView protein in SMART
SM00248. ANK. 5 hits.
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.

Sequencei

Sequence statusi: Complete.

Q0VFY6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADGPDEYET ETGCVPLLHP EEIKPQSHYN HGYGEPLGRK THIDDYSTWD
60 70 80 90 100
IVKATQYGIY ERCRELVEAG YDVRQPDKEN VTLLHWAAIN NRIDLVKYYI
110 120 130 140 150
SKGAIVDQLG GDLNSTPLHW ATRQGHLSMV VQLMKYGADP SLIDGEGCSC
160 170 180 190 200
IHLAAQFGHT SIVAYLIAKG QDVDMMDQNG MTPLMWAAYR THSVDPTRLL
210 220 230 240 250
LTFNVSVNLG DKYHKNTALH WAVLAGNTTV ISLLLEAGGN VDAQNVKGES
260 270 280 290 300
ALDLAKQRKN VWMINHLQEA RQAKGYDNPS FLRKLKADKE FRQKVMLGTP
310 320 330 340 350
FLVIWLVGFI ADLDIDSWLI KGLMYGGVWA TVQFLSKSFF DHSMHSALPL
360 370 380 390 400
GIYLATKFWM YVTWFFWFWN DLNFLFIHLP FLANSVALFY NFGKSWKSDP
410 420 430 440 450
GIIKATEEQK KKTIVELAET GSLDLSIFCS TCLIRKPVRS KHCGVCNRCI
460 470 480 490 500
AKFDHHCPWV GNCVGAGNHR YFMGYLFFLL FMICWMIYGC VSYWGLHCET
510 520 530 540 550
TYTKDGFWTY ITQIATCSPW MFWMFLNSVF HFLWVAVLLM CQLYQITCLG
560 570 580 590 600
ITTNERMNAR RYKHFKVTTT SIESPFNHGC VRNIIDFFEF RCCGLFRPVI
610 620
VDWTRQYTIE YDQISGSGYQ LV
Length:622
Mass (Da):71,399
Last modified:September 5, 2006 - v1
Checksum:i5E60AAF37874387E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC117788 mRNA. Translation: AAI17789.1.
BC117789 mRNA. Translation: AAI17790.1.
CH466539 Genomic DNA. Translation: EDL21720.1.
UniGeneiMm.339281.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC117788 mRNA. Translation: AAI17789.1.
BC117789 mRNA. Translation: AAI17790.1.
CH466539 Genomic DNA. Translation: EDL21720.1.
UniGeneiMm.339281.

3D structure databases

ProteinModelPortaliQ0VFY6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000043279.

Proteomic databases

PeptideAtlasiQ0VFY6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:2445110. Zdhhc17.

Phylogenomic databases

eggNOGiKOG0509. Eukaryota.
COG0666. LUCA.
COG5273. LUCA.
HOVERGENiHBG051907.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000035798.

Family and domain databases

Gene3Di1.25.40.20. 2 hits.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR001594. Palmitoyltrfase_DHHC.
IPR030289. ZDHHC17.
PANTHERiPTHR24161:SF39. PTHR24161:SF39. 1 hit.
PfamiView protein in Pfam
PF12796. Ank_2. 2 hits.
PF01529. zf-DHHC. 1 hit.
PRINTSiPR01415. ANKYRIN.
SMARTiView protein in SMART
SM00248. ANK. 5 hits.
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ0VFY6_MOUSE
AccessioniPrimary (citable) accession number: Q0VFY6
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: April 12, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.