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Q0VF99 (Q0VF99_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Oxysterol-binding protein RuleBase RU003845
Gene names
Name:OSBP2 EMBL AAI18915.1 Ensembl ENSP00000392080
ORF Names:RP3-430N8.7-005 EMBL CAQ07397.1
OrganismHomo sapiens (Human) EMBL AAI18915.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length915 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the OSBP family. RuleBase RU003844

Contains 1 PH domain. RuleBase RU003350

Ontologies

Keywords
   Biological processLipid transport RuleBase RU003845
Transport
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processlipid transport

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q0VF99 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 383DAC37FA97D07D

FASTA915101,179
        10         20         30         40         50         60 
MGKAAAPSRG GGCGGRSRGL SSLFTVVPCL SCHTAAPGMS ASTSGSGPEP KPQPQPVPEP 

        70         80         90        100        110        120 
ERGPLSEQVS EAVSEAVPRS EPVSETTSEP EPGAGQPSEL LQGSRPGSES SSGVGAGPFT 

       130        140        150        160        170        180 
KAASEPLSRA VGSATFLRPE SGSLPALKPL PLLRPGQAKT PLGVPMSGTG TTSSAPLALL 

       190        200        210        220        230        240 
PLDSFEGWLL KWTNYLKGYQ RRWFVLGNGL LSYYRNQGEM AHTCRGTINL STAHIDTEDS 

       250        260        270        280        290        300 
CGILLTSGAR SYHLKASSEV DRQQWITALE LAKAKAVRVM NTHSDDSGDD DEATTPADKS 

       310        320        330        340        350        360 
ELHHTLKNLS LKLDDLSTCN DLIAKHGAAL QRSLTELDGL KIPSESGEKL KVVNERATLF 

       370        380        390        400        410        420 
RITSNAMINA CRDFLELAEI HSRKWQRALQ YEQEQRVHLE ETIEQLAKQH NSLERAFHSA 

       430        440        450        460        470        480 
PGRPANPSKS FIEGSLLTPK GEDSEEDEDT EYFDAMEDST SFITVITEAK EDRKAEGSTG 

       490        500        510        520        530        540 
TSSVDWSSAD NVLDGASLVP KGSSKVKRRV RIPNKPNYSL NLWSIMKNCI GRELSRIPMP 

       550        560        570        580        590        600 
VNFNEPLSML QRLTEDLEYH HLLDKAVHCT SSVEQMCLVA AFSVSSYSTT VHRIAKPFNP 

       610        620        630        640        650        660 
MLGETFELDR LDDMGLRSLC EQVSHHPPSA AHYVFSKHGW SLWQEITISS KFRGKYISIM 

       670        680        690        700        710        720 
PLGAIHLEFQ ASGNHYVWRK STSTVHNIIV GKLWIDQSGD IEIVNHKTND RCQLKFLPYS 

       730        740        750        760        770        780 
YFSKEAARKV TGVVSDSQGK AHYVLSGSWD EQMECSKVMH SSPSSPSSDG KQKTVYQTLS 

       790        800        810        820        830        840 
AKLLWKKYPL PENAENMYYF SELALTLNEH EEGVAPTDSR LRPDQRLMEK GRWDEANTEK 

       850        860        870        880        890        900 
QRLEEKQRLS RRRRLEACGP GSSCSSEEEK EADAYTPLWF EKRLDPLTGE MACVYKGGYW 

       910 
EAKEKQDWHM CPNIF 

« Hide

References

« Hide 'large scale' references
[1]"The DNA sequence of human chromosome 22."
Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M. expand/collapse author list , Buck D., Burgess J., Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y., Wright H.
Nature 402:489-495(1999) [PubMed: 10591208] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: PCR rescued clones EMBL AAI18915.1.
[3]Bird C.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[4]Steward C.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[5]Ensembl
Submitted (JUL-2011) to UniProtKB
Cited for: IDENTIFICATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC118914 mRNA. Translation: AAI18915.1.
AL079299, AC004542, AL022336 Genomic DNA. Translation: CAQ07397.1.
AL022336, AC004542, AL079299 Genomic DNA. Translation: CAQ07893.1.
IPIIPI00878043.
UniGeneHs.517546.

3D structure databases

ProteinModelPortalQ0VF99.
SMRQ0VF99. Positions 7-43, 182-277.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0VF99.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000446658; ENSP00000392080; ENSG00000184792.

Organism-specific databases

HGNCHGNC:8504. OSBP2.
GenAtlasSearch...

Phylogenomic databases

HOVERGENHBG053374.

Gene expression databases

ArrayExpressQ0VF99.
BgeeQ0VF99.

Family and domain databases

InterProIPR000648. Oxysterol-bd.
IPR018494. Oxysterol-bd_CS.
IPR011993. PH_type.
IPR001849. Pleckstrin_homology.
[Graphical view]
Gene3DG3DSA:2.30.29.30. PH_type. 1 hit.
PANTHERPTHR10972. Oxysterol_bd. 1 hit.
PfamPF01237. Oxysterol_BP. 1 hit.
PF00169. PH. 1 hit.
[Graphical view]
SMARTSM00233. PH. 1 hit.
[Graphical view]
PROSITEPS01013. OSBP. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ0VF99_HUMAN
AccessionPrimary (citable) accession number: Q0VF99
Entry history
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: November 16, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.