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Protein
Submitted name:

Regulating synaptic membrane exocytosis protein 2

Gene

Rims2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri86 – 142FYVE-typePROSITE-ProRule annotationAdd BLAST57

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Regulating synaptic membrane exocytosis protein 2Imported
Submitted name:
Rims2 proteinImported
Gene namesi
Name:Rims2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:2152972 Rims2

Subcellular locationi

PTM / Processingi

PTM databases

iPTMnetiQ0VF51

Expressioni

Gene expression databases

GenevisibleiQ0VF51 MM

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ0VF51
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 154RabBDInterPro annotationAdd BLAST129
Domaini86 – 142FYVE-typeInterPro annotationAdd BLAST57
Domaini637 – 723PDZInterPro annotationAdd BLAST87
Domaini787 – 882C2InterPro annotationAdd BLAST96
Domaini1410 – 1498C2InterPro annotationAdd BLAST89

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili44 – 85Sequence analysisAdd BLAST42

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri86 – 142FYVE-typePROSITE-ProRule annotationAdd BLAST57

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2060 Eukaryota
KOG3799 Eukaryota
ENOG410ZNB1 LUCA
GeneTreeiENSGT00550000074588
HOGENOMiHOG000082403
HOVERGENiHBG058147

Family and domain databases

Gene3Di2.60.40.150, 2 hits
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR001478 PDZ
IPR036034 PDZ_sf
IPR010911 Rab_BD
IPR030631 RIM2
IPR017455 Znf_FYVE-rel
IPR011011 Znf_FYVE_PHD
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR12157:SF15 PTHR12157:SF15, 1 hit
PfamiView protein in Pfam
PF00168 C2, 2 hits
SMARTiView protein in SMART
SM00239 C2, 2 hits
SM00228 PDZ, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
SSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS50004 C2, 2 hits
PS50106 PDZ, 1 hit
PS50916 RABBD, 1 hit
PS50178 ZF_FYVE, 1 hit

Sequencei

Sequence statusi: Complete.

Q0VF51-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAPLGPRGR PAPTPAASQP PPQPEMPDLS HLTEEERKII LAVMDRQKKE
60 70 80 90 100
EEKEQSVLKK LHQQFEMYKE QVKKMGEESQ QQQEQKGDAP TCGICHKTKF
110 120 130 140 150
ADGCGHNCSY CQTKFCARCG GRVSLRSNKV MWVCNLCRKQ QEILTKSGAW
160 170 180 190 200
FYNSGSNTLQ QPDQKVPRGL RNEEAPQEKK AKLHEQPQFQ GAPGDLSVPA
210 220 230 240 250
VEKGRAHGLT RQDTIKNGSG VKHQIASDMP SDRKRSPSVS RDQNRRYEQS
260 270 280 290 300
EEREDYSQYV PSDGTMPRSP SDYADRRSQR EPQFYEEPGH LNYRDSNRRG
310 320 330 340 350
HRHSKEYIVD DEDVESRDEY ERQRREEEYQ ARYRSDPNLA RYPVKPQPYE
360 370 380 390 400
EQMRIHAEVS RARHERRHSD VSLANAELED SRISLLRMDR PSRQRSVSER
410 420 430 440 450
RAAMENQRSY SMERTREAQG QSSYPQRTSN HSPPTPRRSP IPLDRPDMRR
460 470 480 490 500
ADSLRKQHHL DPSSAVRKTK REKMETMLRN DSLSSDQSES VRPPPPRPHK
510 520 530 540 550
SKKGGKMRQV SLSSSEEELA STPEYTSCDD VELESESVSE KGDSQKGKRK
560 570 580 590 600
TSEQGVLSDS NTRSERQKKR MYYGGHSLEE DLEWSEPQIK DSGVDTCSST
610 620 630 640 650
TLNEEHSHSD KHPVTWQPSK DGDRLIGRIL LNKRLKDGSV PRDSGAMLGL
660 670 680 690 700
KVVGGKMTES GRLCAFITKV KKGSLADTVG HLRPGDEVLE WNGRLLQGAT
710 720 730 740 750
FEEVYNIILE SKPEPQVELV VSRPIGDIPR IPDSTHAQLE SSSSSFESQK
760 770 780 790 800
MDRPSISVTS PMSPGMLRDV PQFLSGQLSI KLWFDKVGHQ LIVTILGAKD
810 820 830 840 850
LPSREDGRPR NPYVKIYFLP DRSDKNKRRT KTVKKTLEPK WNQTFIYSPV
860 870 880 890 900
HRREFRERML EITLWDQARV REEESEFLGE ILIELETALL DDEPHWYKLQ
910 920 930 940 950
THDVSSLPLP RPSPYLPRRQ LHGESPTRRL QRSKRISDSE VSDYDCEDGV
960 970 980 990 1000
GVVSDYRHNG RDLQSSTLSV PEQVMSSNHC SPSGSPHRVD VIGRTRSWSP
1010 1020 1030 1040 1050
SAPPPQRNVE QGHRGTRATG HYNTISRMDR HRVMDDHYSS DRDRDCEAAD
1060 1070 1080 1090 1100
RQPYHRSRST EQRPLLERTT TRSRSSERPD TNLMRSMPSL MTGRSAPPSP
1110 1120 1130 1140 1150
ALSRSHPRTG SVQTSPSSTP GTGRRGRQLP QLPPKGTLER SAMDIEERNR
1160 1170 1180 1190 1200
QMKLNKYKQV AGSDPRLEQD YHSKYRSGWD PHRGADTVST KSSDSDVSDV
1210 1220 1230 1240 1250
SAVSRTSSAS RFSSTSYMSV QSERPRGNRK ISVFTSKMQN RQMGVSGKNL
1260 1270 1280 1290 1300
TKSTSISGDM CSLEKNDGSQ SDTAVGALGT SGKKRRSSIG AKMVAIVGLS
1310 1320 1330 1340 1350
RKSRSASQLS QTEGGGKKLR STVQRSTETG LAVEMRNWMT RQASRESTDG
1360 1370 1380 1390 1400
SMNSYSSEGN LIFPGVRLAS DSQFSDFLDG LGPAQLVGRQ TLATPAMGDI
1410 1420 1430 1440 1450
QVGMMDKKGQ LEVEIIRARG LVVKPGSKTL PAPYVKVYLL DNGVCIAKKK
1460 1470 1480 1490 1500
TKVARKTLEP LYQQLLSFEE SPQGRVLQII VWGDYGRMDH KSFMGVAQIL
1510 1520 1530 1540 1550
LDELELSNMV IGWFKLFPPS SLVDPTLAPL TRRASQSSLE SSTGPSYSRS
Length:1,550
Mass (Da):175,005
Last modified:September 5, 2006 - v1
Checksum:i7EA17D49A9152C80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC101886 Genomic DNA No translation available.
AC101935 Genomic DNA No translation available.
AC114537 Genomic DNA No translation available.
BC118979 mRNA Translation: AAI18980.1
RefSeqiNP_001243312.1, NM_001256383.1
UniGeneiMm.309296

Genome annotation databases

EnsembliENSMUST00000227243; ENSMUSP00000154153; ENSMUSG00000037386
GeneIDi116838
UCSCiuc007voe.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ0VF51_MOUSE
AccessioniPrimary (citable) accession number: Q0VF51
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: May 23, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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