Rims2 protein

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• metal ion binding Source: UniProtKB-KW

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• calcium ion-regulated exocytosis of neurotransmitter Source: InterPro
• intracellular protein transport Source: InterPro
• regulation of exocytosis Source: InterPro

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Ligandⁱ

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>Provides information on the location and the topology of the mature protein in the cell.</p><p><a href='../manual/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Cellular componentⁱ

• intracellular Source: GOC
• presynaptic active zone Source: InterPro

<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Proteomic databases

PTM databases

<p>Provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.</p><p><a href='../manual/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactionⁱ

Protein-protein interaction databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
<p>Describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.</p><p><a href='../manual/domain' target='_top'>More...</a></p>Domaini	26 – 154	129	RabBD (Rab-binding)InterPro annotation <p>Information which has been generated by the UniProtKB automatic annotation system, without manual validation.</p> <p><a href="/manual/evidences#ECO:0000259">More…</a></p> Automatic assertion inferred from signature matchi PROSITE:PS50916			Add BLAST
<p>Describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.</p><p><a href='../manual/domain' target='_top'>More...</a></p>Domaini	86 – 142	57	FYVE-typeInterPro annotation <p>Information which has been generated by the UniProtKB automatic annotation system, without manual validation.</p> <p><a href="/manual/evidences#ECO:0000259">More…</a></p> Automatic assertion inferred from signature matchi PROSITE:PS50178			Add BLAST
<p>Describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.</p><p><a href='../manual/domain' target='_top'>More...</a></p>Domaini	637 – 723	87	PDZ (DHR)InterPro annotation <p>Information which has been generated by the UniProtKB automatic annotation system, without manual validation.</p> <p><a href="/manual/evidences#ECO:0000259">More…</a></p> Automatic assertion inferred from signature matchi PROSITE:PS50106			Add BLAST
<p>Describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.</p><p><a href='../manual/domain' target='_top'>More...</a></p>Domaini	787 – 882	96	C2InterPro annotation <p>Information which has been generated by the UniProtKB automatic annotation system, without manual validation.</p> <p><a href="/manual/evidences#ECO:0000259">More…</a></p> Automatic assertion inferred from signature matchi PROSITE:PS50004			Add BLAST
<p>Describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.</p><p><a href='../manual/domain' target='_top'>More...</a></p>Domaini	1410 – 1498	89	C2InterPro annotation <p>Information which has been generated by the UniProtKB automatic annotation system, without manual validation.</p> <p><a href="/manual/evidences#ECO:0000259">More…</a></p> Automatic assertion inferred from signature matchi PROSITE:PS50004			Add BLAST

Coiled coil

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
<p>Denotes the positions of regions of coiled coil within the protein.</p><p><a href='../manual/coiled' target='_top'>More...</a></p>Coiled coili	44 – 85	42	Sequence analysis <p>Information which has been generated by the UniProtKB automatic annotation system, without manual validation.</p> <p><a href="/manual/evidences#ECO:0000256">More…</a></p> Automatic assertion according to rulesi SAM:Coils			Add BLAST

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>Indicates if the <a href="/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.</p><p><a href='../manual/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MSAPLGPRGR PAPTPAASQP PPQPEMPDLS HLTEEERKII LAVMDRQKKE 
        60         70         80         90        100
EEKEQSVLKK LHQQFEMYKE QVKKMGEESQ QQQEQKGDAP TCGICHKTKF 
       110        120        130        140        150
ADGCGHNCSY CQTKFCARCG GRVSLRSNKV MWVCNLCRKQ QEILTKSGAW 
       160        170        180        190        200
FYNSGSNTLQ QPDQKVPRGL RNEEAPQEKK AKLHEQPQFQ GAPGDLSVPA 
       210        220        230        240        250
VEKGRAHGLT RQDTIKNGSG VKHQIASDMP SDRKRSPSVS RDQNRRYEQS 
       260        270        280        290        300
EEREDYSQYV PSDGTMPRSP SDYADRRSQR EPQFYEEPGH LNYRDSNRRG 
       310        320        330        340        350
HRHSKEYIVD DEDVESRDEY ERQRREEEYQ ARYRSDPNLA RYPVKPQPYE 
       360        370        380        390        400
EQMRIHAEVS RARHERRHSD VSLANAELED SRISLLRMDR PSRQRSVSER 
       410        420        430        440        450
RAAMENQRSY SMERTREAQG QSSYPQRTSN HSPPTPRRSP IPLDRPDMRR 
       460        470        480        490        500
ADSLRKQHHL DPSSAVRKTK REKMETMLRN DSLSSDQSES VRPPPPRPHK 
       510        520        530        540        550
SKKGGKMRQV SLSSSEEELA STPEYTSCDD VELESESVSE KGDSQKGKRK 
       560        570        580        590        600
TSEQGVLSDS NTRSERQKKR MYYGGHSLEE DLEWSEPQIK DSGVDTCSST 
       610        620        630        640        650
TLNEEHSHSD KHPVTWQPSK DGDRLIGRIL LNKRLKDGSV PRDSGAMLGL 
       660        670        680        690        700
KVVGGKMTES GRLCAFITKV KKGSLADTVG HLRPGDEVLE WNGRLLQGAT 
       710        720        730        740        750
FEEVYNIILE SKPEPQVELV VSRPIGDIPR IPDSTHAQLE SSSSSFESQK 
       760        770        780        790        800
MDRPSISVTS PMSPGMLRDV PQFLSGQLSI KLWFDKVGHQ LIVTILGAKD 
       810        820        830        840        850
LPSREDGRPR NPYVKIYFLP DRSDKNKRRT KTVKKTLEPK WNQTFIYSPV 
       860        870        880        890        900
HRREFRERML EITLWDQARV REEESEFLGE ILIELETALL DDEPHWYKLQ 
       910        920        930        940        950
THDVSSLPLP RPSPYLPRRQ LHGESPTRRL QRSKRISDSE VSDYDCEDGV 
       960        970        980        990       1000
GVVSDYRHNG RDLQSSTLSV PEQVMSSNHC SPSGSPHRVD VIGRTRSWSP 
      1010       1020       1030       1040       1050
SAPPPQRNVE QGHRGTRATG HYNTISRMDR HRVMDDHYSS DRDRDCEAAD 
      1060       1070       1080       1090       1100
RQPYHRSRST EQRPLLERTT TRSRSSERPD TNLMRSMPSL MTGRSAPPSP 
      1110       1120       1130       1140       1150
ALSRSHPRTG SVQTSPSSTP GTGRRGRQLP QLPPKGTLER SAMDIEERNR 
      1160       1170       1180       1190       1200
QMKLNKYKQV AGSDPRLEQD YHSKYRSGWD PHRGADTVST KSSDSDVSDV 
      1210       1220       1230       1240       1250
SAVSRTSSAS RFSSTSYMSV QSERPRGNRK ISVFTSKMQN RQMGVSGKNL 
      1260       1270       1280       1290       1300
TKSTSISGDM CSLEKNDGSQ SDTAVGALGT SGKKRRSSIG AKMVAIVGLS 
      1310       1320       1330       1340       1350
RKSRSASQLS QTEGGGKKLR STVQRSTETG LAVEMRNWMT RQASRESTDG 
      1360       1370       1380       1390       1400
SMNSYSSEGN LIFPGVRLAS DSQFSDFLDG LGPAQLVGRQ TLATPAMGDI 
      1410       1420       1430       1440       1450
QVGMMDKKGQ LEVEIIRARG LVVKPGSKTL PAPYVKVYLL DNGVCIAKKK 
      1460       1470       1480       1490       1500
TKVARKTLEP LYQQLLSFEE SPQGRVLQII VWGDYGRMDH KSFMGVAQIL 
      1510       1520       1530       1540       1550
LDELELSNMV IGWFKLFPPS SLVDPTLAPL TRRASQSSLE SSTGPSYSRS 

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>Provides links to the UniProt Reference Clusters (<a href="/help/uniref">UniRef</a>). UniRef consists of clusters for UniProtKB sequences (including isoforms) and selected UniParc sequences, in order to obtain complete coverage of the sequence space at resolutions of 100%, 90% and 50% identity.</p><p><a href='../manual/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ