Rims2

Functionⁱ

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	86 – 142	FYVE-typePROSITE-ProRule annotationAdd BLAST		57

GO - Molecular functionⁱ

metal ion binding Source: UniProtKB-KW
Rab GTPase binding Source: InterPro

Complete GO annotation...

GO - Biological processⁱ

calcium ion-regulated exocytosis of neurotransmitter Source: InterPro
intracellular protein transport Source: InterPro
regulation of exocytosis Source: InterPro

Complete GO annotation...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Rims2 proteinImported
Gene namesⁱ	Name:Rims2Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus

Organism-specific databases

MGIⁱ	MGI:2152972. Rims2.

Subcellular locationⁱ

GO (Gene Ontology) annotation

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q0VF51.
PaxDbⁱ	Q0VF51.
PRIDEⁱ	Q0VF51.

PTM databases

iPTMnetⁱ	Q0VF51.

iPTMnetⁱ

Q0VF51.

Expressionⁱ

Gene expression databases

Genevisibleⁱ	Q0VF51. MM.

Genevisibleⁱ

Q0VF51. MM.

Interactionⁱ

GO - Molecular functionⁱ

Rab GTPase binding Source: InterPro

Complete GO annotation...

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q0VF51.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	26 – 154	RabBDInterPro annotationAdd BLAST	129
Domainⁱ	86 – 142	FYVE-typeInterPro annotationAdd BLAST	57
Domainⁱ	637 – 723	PDZInterPro annotationAdd BLAST	87
Domainⁱ	787 – 882	C2InterPro annotationAdd BLAST	96
Domainⁱ	1410 – 1498	C2InterPro annotationAdd BLAST	89

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	44 – 85	Sequence analysisAdd BLAST		42

Zinc finger

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	86 – 142	FYVE-typePROSITE-ProRule annotationAdd BLAST		57

Keywords - Domainⁱ

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG2060. Eukaryota. KOG3799. Eukaryota. ENOG410ZNB1. LUCA.
HOGENOMⁱ	HOG000082403.
HOVERGENⁱ	HBG058147.

Family and domain databases

Gene3Dⁱ	2.60.40.150. 2 hits. 3.30.40.10. 1 hit.
InterProⁱ	View protein in InterPro IPR000008. C2_dom. IPR001478. PDZ. IPR010911. Rab_BD. IPR030631. RIM2. IPR017455. Znf_FYVE-rel. IPR011011. Znf_FYVE_PHD. IPR013083. Znf_RING/FYVE/PHD.
PANTHERⁱ	PTHR12157:SF23. PTHR12157:SF23. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00168. C2. 2 hits. PF02318. FYVE_2. 1 hit.
SMARTⁱ	View protein in SMART SM00239. C2. 2 hits. SM00228. PDZ. 1 hit.
SUPFAMⁱ	SSF49562. SSF49562. 2 hits. SSF50156. SSF50156. 1 hit. SSF57903. SSF57903. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50004. C2. 2 hits. PS50106. PDZ. 1 hit. PS50916. RABBD. 1 hit. PS50178. ZF_FYVE. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q0VF51-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSAPLGPRGR PAPTPAASQP PPQPEMPDLS HLTEEERKII LAVMDRQKKE 
        60         70         80         90        100
EEKEQSVLKK LHQQFEMYKE QVKKMGEESQ QQQEQKGDAP TCGICHKTKF 
       110        120        130        140        150
ADGCGHNCSY CQTKFCARCG GRVSLRSNKV MWVCNLCRKQ QEILTKSGAW 
       160        170        180        190        200
FYNSGSNTLQ QPDQKVPRGL RNEEAPQEKK AKLHEQPQFQ GAPGDLSVPA 
       210        220        230        240        250
VEKGRAHGLT RQDTIKNGSG VKHQIASDMP SDRKRSPSVS RDQNRRYEQS 
       260        270        280        290        300
EEREDYSQYV PSDGTMPRSP SDYADRRSQR EPQFYEEPGH LNYRDSNRRG 
       310        320        330        340        350
HRHSKEYIVD DEDVESRDEY ERQRREEEYQ ARYRSDPNLA RYPVKPQPYE 
       360        370        380        390        400
EQMRIHAEVS RARHERRHSD VSLANAELED SRISLLRMDR PSRQRSVSER 
       410        420        430        440        450
RAAMENQRSY SMERTREAQG QSSYPQRTSN HSPPTPRRSP IPLDRPDMRR 
       460        470        480        490        500
ADSLRKQHHL DPSSAVRKTK REKMETMLRN DSLSSDQSES VRPPPPRPHK 
       510        520        530        540        550
SKKGGKMRQV SLSSSEEELA STPEYTSCDD VELESESVSE KGDSQKGKRK 
       560        570        580        590        600
TSEQGVLSDS NTRSERQKKR MYYGGHSLEE DLEWSEPQIK DSGVDTCSST 
       610        620        630        640        650
TLNEEHSHSD KHPVTWQPSK DGDRLIGRIL LNKRLKDGSV PRDSGAMLGL 
       660        670        680        690        700
KVVGGKMTES GRLCAFITKV KKGSLADTVG HLRPGDEVLE WNGRLLQGAT 
       710        720        730        740        750
FEEVYNIILE SKPEPQVELV VSRPIGDIPR IPDSTHAQLE SSSSSFESQK 
       760        770        780        790        800
MDRPSISVTS PMSPGMLRDV PQFLSGQLSI KLWFDKVGHQ LIVTILGAKD 
       810        820        830        840        850
LPSREDGRPR NPYVKIYFLP DRSDKNKRRT KTVKKTLEPK WNQTFIYSPV 
       860        870        880        890        900
HRREFRERML EITLWDQARV REEESEFLGE ILIELETALL DDEPHWYKLQ 
       910        920        930        940        950
THDVSSLPLP RPSPYLPRRQ LHGESPTRRL QRSKRISDSE VSDYDCEDGV 
       960        970        980        990       1000
GVVSDYRHNG RDLQSSTLSV PEQVMSSNHC SPSGSPHRVD VIGRTRSWSP 
      1010       1020       1030       1040       1050
SAPPPQRNVE QGHRGTRATG HYNTISRMDR HRVMDDHYSS DRDRDCEAAD 
      1060       1070       1080       1090       1100
RQPYHRSRST EQRPLLERTT TRSRSSERPD TNLMRSMPSL MTGRSAPPSP 
      1110       1120       1130       1140       1150
ALSRSHPRTG SVQTSPSSTP GTGRRGRQLP QLPPKGTLER SAMDIEERNR 
      1160       1170       1180       1190       1200
QMKLNKYKQV AGSDPRLEQD YHSKYRSGWD PHRGADTVST KSSDSDVSDV 
      1210       1220       1230       1240       1250
SAVSRTSSAS RFSSTSYMSV QSERPRGNRK ISVFTSKMQN RQMGVSGKNL 
      1260       1270       1280       1290       1300
TKSTSISGDM CSLEKNDGSQ SDTAVGALGT SGKKRRSSIG AKMVAIVGLS 
      1310       1320       1330       1340       1350
RKSRSASQLS QTEGGGKKLR STVQRSTETG LAVEMRNWMT RQASRESTDG 
      1360       1370       1380       1390       1400
SMNSYSSEGN LIFPGVRLAS DSQFSDFLDG LGPAQLVGRQ TLATPAMGDI 
      1410       1420       1430       1440       1450
QVGMMDKKGQ LEVEIIRARG LVVKPGSKTL PAPYVKVYLL DNGVCIAKKK 
      1460       1470       1480       1490       1500
TKVARKTLEP LYQQLLSFEE SPQGRVLQII VWGDYGRMDH KSFMGVAQIL 
      1510       1520       1530       1540       1550
LDELELSNMV IGWFKLFPPS SLVDPTLAPL TRRASQSSLE SSTGPSYSRS

Length:1,550

Mass (Da):175,005

Last modified:September 5, 2006 - v1

Checksum:ⁱ7EA17D49A9152C80

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC118979 mRNA. Translation: AAI18980.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001243312.1. NM_001256383.1.
UniGeneⁱ	Mm.309296.

Genome annotation databases

GeneIDⁱ	116838.
UCSC genome browser More...UCSCⁱ	uc007voe.2. mouse.

Similar proteinsⁱ

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q0VF51	UPI0007EE723C UPI0007EC4488 UPI00046BD009 UPI000945CBE7 UPI00045E4539 UPI000A28947C UPI00027FAE82 UPI0002C59AF7 UPI000328E73E UPI00032AEB33 +30	Mus musculus (Mouse) Oryctolagus cuniculus (Rabbit) Eptesicus fuscus (Big brown bat) (Vespertilio fuscus) Rhinolophus sinicus (Chinese rufous horseshoe bat) Orycteropus afer afer Phascolarctos cinereus (Koala) Saimiri boliviensis boliviensis (Bolivian squirrel monkey) Odobenus rosmarus divergens (Pacific walrus) Dasypus novemcinctus (Nine-banded armadillo) Ochotona princeps (Southern American pika) And more	1,550	UniRef90_Q0VF51	Cluster: Rims2 protein	41

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q0VF51	Q9UQ26-1 UPI0007DC5A02 UPI0006B6A2CE UPI000771424E UPI0003AE5B78 UPI0007DC63FB UPI00083C1B3D UPI00083C17F7 UPI00083BE9C7 UPI0004ED71CE +412	Homo sapiens (Human) Zonotrichia albicollis (White-throated sparrow) Parus major (Great tit) Canis lupus familiaris (Dog) (Canis familiaris) Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti) Nannospalax galili (Northern Israeli blind subterranean mole rat) (Spalax galili) Mesocricetus auratus (Golden hamster) Bos taurus (Bovine) Equus asinus (Donkey) (Equus africanus asinus) Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys) And more	1,188	UniRef50_Q9UQ26-1	Cluster: Isoform 1 of Regulating synaptic membrane exocytosis protein 2	423

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC118979 mRNA. Translation: AAI18980.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001243312.1. NM_001256383.1.
UniGeneⁱ	Mm.309296.

3D structure databases

ProteinModelPortalⁱ	Q0VF51.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

PTM databases

iPTMnetⁱ	Q0VF51.

iPTMnetⁱ

Q0VF51.

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q0VF51.
PaxDbⁱ	Q0VF51.
PRIDEⁱ	Q0VF51.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	116838.
UCSC genome browser More...UCSCⁱ	uc007voe.2. mouse.

Organism-specific databases

CTDⁱ	9699.
MGIⁱ	MGI:2152972. Rims2.

Phylogenomic databases

eggNOGⁱ	KOG2060. Eukaryota. KOG3799. Eukaryota. ENOG410ZNB1. LUCA.
HOGENOMⁱ	HOG000082403.
HOVERGENⁱ	HBG058147.

Miscellaneous databases

SOURCEⁱ	Search...

SOURCEⁱ

Search...

Gene expression databases

Genevisibleⁱ	Q0VF51. MM.

Genevisibleⁱ

Q0VF51. MM.

Family and domain databases

Gene3Dⁱ	2.60.40.150. 2 hits. 3.30.40.10. 1 hit.
InterProⁱ	View protein in InterPro IPR000008. C2_dom. IPR001478. PDZ. IPR010911. Rab_BD. IPR030631. RIM2. IPR017455. Znf_FYVE-rel. IPR011011. Znf_FYVE_PHD. IPR013083. Znf_RING/FYVE/PHD.
PANTHERⁱ	PTHR12157:SF23. PTHR12157:SF23. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00168. C2. 2 hits. PF02318. FYVE_2. 1 hit.
SMARTⁱ	View protein in SMART SM00239. C2. 2 hits. SM00228. PDZ. 1 hit.
SUPFAMⁱ	SSF49562. SSF49562. 2 hits. SSF50156. SSF50156. 1 hit. SSF57903. SSF57903. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50004. C2. 2 hits. PS50106. PDZ. 1 hit. PS50916. RABBD. 1 hit. PS50178. ZF_FYVE. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q0VF51_MOUSE
Accessionⁱ	Q0VF51Primary (citable) accession number: Q0VF51
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	September 5, 2006
	Last sequence update:	September 5, 2006
	Last modified:	September 27, 2017
	This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

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UniProtKB - Q0VF51 (Q0VF51_MOUSE)

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Rims2 protein

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Zinc finger

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ