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Q0VEX8

- Q0VEX8_MOUSE

UniProt

Q0VEX8 - Q0VEX8_MOUSE

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Protein
Submitted name: Gamma-aminobutyric acid (GABA-A) receptor, subunit theta
Gene
Gabrq
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. GABA-A receptor activity Source: MGI
  2. extracellular ligand-gated ion channel activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. chloride transport Source: MGI
  2. gamma-aminobutyric acid signaling pathway Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotations, ReceptorImported

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Gamma-aminobutyric acid (GABA-A) receptor, subunit thetaImported
Gene namesi
Name:GabrqImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1888498. Gabrq.

Subcellular locationi

GO - Cellular componenti

  1. cell junction Source: UniProtKB-KW
  2. integral component of plasma membrane Source: MGI
  3. receptor complex Source: MGI
  4. synapse Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotations, Membrane, SynapseSAAS annotations

Expressioni

Gene expression databases

GenevestigatoriQ0VEX8.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

HOVERGENiHBG051708.
InParanoidiQ0VEX8.
KOiK05192.
OMAiDSIIPTE.

Family and domain databases

Gene3Di2.70.170.10. 1 hit.
InterProiIPR006028. GABAA/Glycine_rcpt.
IPR008101. GABAAt_rcpt.
IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
[Graphical view]
PANTHERiPTHR18945. PTHR18945. 1 hit.
PTHR18945:SF87. PTHR18945:SF87. 1 hit.
PfamiPF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 1 hit.
[Graphical view]
PRINTSiPR00253. GABAARECEPTR.
PR01725. GABAARTHETA.
PR00252. NRIONCHANNEL.
SUPFAMiSSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 3 hits.
TIGRFAMsiTIGR00860. LIC. 1 hit.
PROSITEiPS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0VEX8-1 [UniParc]FASTAAdd to Basket

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MGIRGMLRAA ALLLLIRTWL AESNGPSPTP KFHFELSSST PEVILDLFNC    50
KNCANEAVVQ KILDRVLSTY DVRLRPNFGG APVPVSVSIY VSSIEQISEI 100
NMDYTITMFL HQTWKDTRLA YYETNLNLTL DYRMHEKLWV PDCYFVNSKD 150
AFVHDVTVEN RVFQLHPDGT VRYGIRLTTT AACSLDLQKF PMDKQSCKLE 200
VESYGYTVED IVLSWEDDNA IHITDGLHIP QYTYLGRTIT SKEVYFYTGS 250
YMRLIVKFQV QREVRSYLVQ VYWPTVLTTI LSWISFWMNY DSSAARVTIG 300
LTSILVLTTI DSHMRDKLPH ISCIKAIDIY ILVCLFFVFL SLLEYVYINY 350
LFFSQVPRRN HRRCRKPRRV VARYRYQEVV VANVQDGLIN VEDRVEDRAG 400
PLPDSPMQAH LASQESLGSL VFTSEQAQLA TSESLSLLSS ASSQTQLATG 450
ESLSDLPSTS EQTVPECTIH FHGFLTNDSI IPIKIHSRSD ACDDEDSEES 500
LSSEESHGHG SSHTGRLKLQ ISQRCVQEAS WDLDKIEILQ DDISITSSWL 550
GLDEQCKGDA DSIWSLTDEE LMACDQEKDS SSESEENCSP SPGCSFNEGF 600
SFQLFKPNRV PKVDRWSRFL FPLSFGLFNV VYWLYHVY 638
Length:638
Mass (Da):72,799
Last modified:September 5, 2006 - v1
Checksum:i4E2C4FA02E9BF8A3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC119074 mRNA. Translation: AAI19075.1.
BC119076 mRNA. Translation: AAI19077.1.
RefSeqiNP_065234.1. NM_020488.2.
XP_006528236.1. XM_006528173.1.
UniGeneiMm.117125.
Mm.487532.

Genome annotation databases

GeneIDi57249.
KEGGimmu:57249.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC119074 mRNA. Translation: AAI19075.1 .
BC119076 mRNA. Translation: AAI19077.1 .
RefSeqi NP_065234.1. NM_020488.2.
XP_006528236.1. XM_006528173.1.
UniGenei Mm.117125.
Mm.487532.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 57249.
KEGGi mmu:57249.

Organism-specific databases

CTDi 55879.
MGIi MGI:1888498. Gabrq.

Phylogenomic databases

HOVERGENi HBG051708.
InParanoidi Q0VEX8.
KOi K05192.
OMAi DSIIPTE.

Miscellaneous databases

NextBioi 313527.
SOURCEi Search...

Gene expression databases

Genevestigatori Q0VEX8.

Family and domain databases

Gene3Di 2.70.170.10. 1 hit.
InterProi IPR006028. GABAA/Glycine_rcpt.
IPR008101. GABAAt_rcpt.
IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
[Graphical view ]
PANTHERi PTHR18945. PTHR18945. 1 hit.
PTHR18945:SF87. PTHR18945:SF87. 1 hit.
Pfami PF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 1 hit.
[Graphical view ]
PRINTSi PR00253. GABAARECEPTR.
PR01725. GABAARTHETA.
PR00252. NRIONCHANNEL.
SUPFAMi SSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 3 hits.
TIGRFAMsi TIGR00860. LIC. 1 hit.
PROSITEi PS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.

Entry informationi

Entry nameiQ0VEX8_MOUSE
AccessioniPrimary (citable) accession number: Q0VEX8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: May 14, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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