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Q0VEX8

- Q0VEX8_MOUSE

UniProt

Q0VEX8 - Q0VEX8_MOUSE

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Protein
Submitted name:

Gamma-aminobutyric acid (GABA-A) receptor, subunit theta

Gene

Gabrq

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. extracellular ligand-gated ion channel activity Source: InterPro
  2. GABA-A receptor activity Source: MGI

GO - Biological processi

  1. chloride transport Source: MGI
  2. gamma-aminobutyric acid signaling pathway Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotation, ReceptorImported

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Gamma-aminobutyric acid (GABA-A) receptor, subunit thetaImported
Gene namesi
Name:GabrqImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1888498. Gabrq.

Subcellular locationi

GO - Cellular componenti

  1. cell junction Source: UniProtKB-KW
  2. integral component of plasma membrane Source: MGI
  3. receptor complex Source: MGI
  4. synapse Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, SynapseSAAS annotation

Expressioni

Gene expression databases

GenevestigatoriQ0VEX8.

Family & Domainsi

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOVERGENiHBG051708.
KOiK05192.
OMAiDSIIPTE.

Family and domain databases

Gene3Di2.70.170.10. 1 hit.
InterProiIPR006028. GABAA/Glycine_rcpt.
IPR008101. GABAAt_rcpt.
IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
[Graphical view]
PANTHERiPTHR18945. PTHR18945. 1 hit.
PTHR18945:SF87. PTHR18945:SF87. 1 hit.
PfamiPF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 1 hit.
[Graphical view]
PRINTSiPR00253. GABAARECEPTR.
PR01725. GABAARTHETA.
PR00252. NRIONCHANNEL.
SUPFAMiSSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 3 hits.
TIGRFAMsiTIGR00860. LIC. 1 hit.
PROSITEiPS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0VEX8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGIRGMLRAA ALLLLIRTWL AESNGPSPTP KFHFELSSST PEVILDLFNC
60 70 80 90 100
KNCANEAVVQ KILDRVLSTY DVRLRPNFGG APVPVSVSIY VSSIEQISEI
110 120 130 140 150
NMDYTITMFL HQTWKDTRLA YYETNLNLTL DYRMHEKLWV PDCYFVNSKD
160 170 180 190 200
AFVHDVTVEN RVFQLHPDGT VRYGIRLTTT AACSLDLQKF PMDKQSCKLE
210 220 230 240 250
VESYGYTVED IVLSWEDDNA IHITDGLHIP QYTYLGRTIT SKEVYFYTGS
260 270 280 290 300
YMRLIVKFQV QREVRSYLVQ VYWPTVLTTI LSWISFWMNY DSSAARVTIG
310 320 330 340 350
LTSILVLTTI DSHMRDKLPH ISCIKAIDIY ILVCLFFVFL SLLEYVYINY
360 370 380 390 400
LFFSQVPRRN HRRCRKPRRV VARYRYQEVV VANVQDGLIN VEDRVEDRAG
410 420 430 440 450
PLPDSPMQAH LASQESLGSL VFTSEQAQLA TSESLSLLSS ASSQTQLATG
460 470 480 490 500
ESLSDLPSTS EQTVPECTIH FHGFLTNDSI IPIKIHSRSD ACDDEDSEES
510 520 530 540 550
LSSEESHGHG SSHTGRLKLQ ISQRCVQEAS WDLDKIEILQ DDISITSSWL
560 570 580 590 600
GLDEQCKGDA DSIWSLTDEE LMACDQEKDS SSESEENCSP SPGCSFNEGF
610 620 630
SFQLFKPNRV PKVDRWSRFL FPLSFGLFNV VYWLYHVY
Length:638
Mass (Da):72,799
Last modified:September 5, 2006 - v1
Checksum:i4E2C4FA02E9BF8A3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC119074 mRNA. Translation: AAI19075.1.
BC119076 mRNA. Translation: AAI19077.1.
RefSeqiNP_065234.1. NM_020488.2.
XP_006528236.1. XM_006528173.1.
UniGeneiMm.117125.
Mm.487532.

Genome annotation databases

GeneIDi57249.
KEGGimmu:57249.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC119074 mRNA. Translation: AAI19075.1 .
BC119076 mRNA. Translation: AAI19077.1 .
RefSeqi NP_065234.1. NM_020488.2.
XP_006528236.1. XM_006528173.1.
UniGenei Mm.117125.
Mm.487532.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 57249.
KEGGi mmu:57249.

Organism-specific databases

CTDi 55879.
MGIi MGI:1888498. Gabrq.

Phylogenomic databases

HOVERGENi HBG051708.
KOi K05192.
OMAi DSIIPTE.

Miscellaneous databases

NextBioi 313527.
SOURCEi Search...

Gene expression databases

Genevestigatori Q0VEX8.

Family and domain databases

Gene3Di 2.70.170.10. 1 hit.
InterProi IPR006028. GABAA/Glycine_rcpt.
IPR008101. GABAAt_rcpt.
IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
[Graphical view ]
PANTHERi PTHR18945. PTHR18945. 1 hit.
PTHR18945:SF87. PTHR18945:SF87. 1 hit.
Pfami PF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 1 hit.
[Graphical view ]
PRINTSi PR00253. GABAARECEPTR.
PR01725. GABAARTHETA.
PR00252. NRIONCHANNEL.
SUPFAMi SSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 3 hits.
TIGRFAMsi TIGR00860. LIC. 1 hit.
PROSITEi PS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.

Entry informationi

Entry nameiQ0VEX8_MOUSE
AccessioniPrimary (citable) accession number: Q0VEX8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: October 29, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)