ID   Q0VEJ8_MOUSE            Unreviewed;       223 AA.
AC   Q0VEJ8;
DT   05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2006, sequence version 1.
DT   24-JAN-2024, entry version 122.
DE   SubName: Full=Basic helix-loop-helix family, member e23 {ECO:0000313|EMBL:AAI19211.1};
GN   Name=Bhlhe23 {ECO:0000313|EMBL:AAI19211.1,
GN   ECO:0000313|MGI:MGI:2153710};
GN   Synonyms=Bhlhb4 {ECO:0000313|MGI:MGI:2153710};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|EMBL:AAI19211.1};
RN   [1] {ECO:0000313|EMBL:AAI19211.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain {ECO:0000313|EMBL:AAI19211.1};
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RA   Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA   Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M.,
RA   Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.,
RA   Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F.,
RA   Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T.,
RA   Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F.,
RA   Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E.,
RA   Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y.,
RA   Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E.,
RA   Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y.,
RA   Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W.,
RA   Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA   Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA   Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J.,
RA   Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W.,
RA   Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J.,
RA   Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I.,
RA   Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U.,
RA   Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A.,
RA   Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; BC119208; AAI19209.1; -; mRNA.
DR   EMBL; BC119210; AAI19211.1; -; mRNA.
DR   RefSeq; NP_542372.2; NM_080641.5.
DR   AlphaFoldDB; Q0VEJ8; -.
DR   SMR; Q0VEJ8; -.
DR   Antibodypedia; 29641; 26 antibodies from 13 providers.
DR   DNASU; 140489; -.
DR   GeneID; 140489; -.
DR   KEGG; mmu:140489; -.
DR   AGR; MGI:2153710; -.
DR   CTD; 128408; -.
DR   MGI; MGI:2153710; Bhlhe23.
DR   VEuPathDB; HostDB:ENSMUSG00000045493; -.
DR   HOGENOM; CLU_070971_2_0_1; -.
DR   OMA; AEKCSTY; -.
DR   OrthoDB; 5324482at2759; -.
DR   BioGRID-ORCS; 140489; 0 hits in 79 CRISPR screens.
DR   ExpressionAtlas; Q0VEJ8; baseline and differential.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd18954; bHLH_TS_bHLHe22_bHLHb5; 1.
DR   Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   PANTHER; PTHR19290; BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED; 1.
DR   PANTHER; PTHR19290:SF53; CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 23; 1.
DR   Pfam; PF00010; HLH; 1.
DR   SMART; SM00353; HLH; 1.
DR   SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   2: Evidence at transcript level;
FT   DOMAIN          98..152
FT                   /note="BHLH"
FT                   /evidence="ECO:0000259|PROSITE:PS50888"
FT   REGION          32..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        69..93
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   223 AA;  23701 MW;  68DCD15E0D70C1FA CRC64;
     MAELKSLSGD SYLALSHSYT ATGHAYAAAR GPETTRGFGA SGPGGDLPAA PASRVPAATV
     ESSGEQSGDE DEAFERRRRR RGSGVAVDAR RRPREQRSLR LSINARERRR MHDLNDALDG
     LRAVIPYAHS PSVRKLSKIA TLLLAKNYIL MQAQALEEMR RLVAYLNQGQ GLAAPVAAAP
     LTPFGQAAIY PFSAGTALGP CPDKCATFSG SPSALCKHCG EKP
//