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Protein

Zinc finger protein 800

Gene

Znf800

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri69 – 9123C2H2-type 1; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri231 – 25424C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri288 – 31124C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri357 – 38226C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri484 – 50623C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri517 – 54024C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri616 – 63823C2H2-type 7PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 800
Gene namesi
Name:Znf800
Synonyms:Zfp800
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:1889334. Zfp800.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 662662Zinc finger protein 800PRO_0000304411Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Cross-linki132 – 132Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei318 – 3181PhosphoserineCombined sources
Modified residuei320 – 3201PhosphothreonineBy similarity
Modified residuei337 – 3371PhosphoserineCombined sources
Modified residuei420 – 4201PhosphoserineCombined sources
Modified residuei453 – 4531PhosphoserineBy similarity
Modified residuei455 – 4551PhosphoserineCombined sources
Modified residuei458 – 4581PhosphoserineCombined sources
Modified residuei460 – 4601PhosphoserineCombined sources

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ0VEE6.
MaxQBiQ0VEE6.
PaxDbiQ0VEE6.
PRIDEiQ0VEE6.

PTM databases

iPTMnetiQ0VEE6.
PhosphoSiteiQ0VEE6.

Expressioni

Gene expression databases

BgeeiQ0VEE6.
CleanExiMM_ZFP800.
ExpressionAtlasiQ0VEE6. baseline and differential.
GenevisibleiQ0VEE6. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000039222.

Structurei

3D structure databases

ProteinModelPortaliQ0VEE6.
SMRiQ0VEE6. Positions 70-96, 229-261, 288-318, 349-383, 475-509, 515-540, 609-641.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi12 – 154Poly-His

Sequence similaritiesi

Contains 7 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri69 – 9123C2H2-type 1; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri231 – 25424C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri288 – 31124C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri357 – 38226C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri484 – 50623C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri517 – 54024C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri616 – 63823C2H2-type 7PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00390000008140.
HOGENOMiHOG000168334.
HOVERGENiHBG106061.
InParanoidiQ0VEE6.
OMAiRDKCCQT.
OrthoDBiEOG7F7W80.
TreeFamiTF333197.

Family and domain databases

Gene3Di3.30.160.60. 1 hit.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF16622. zf-C2H2_11. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 7 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 5 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0VEE6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLRDKYCQT DHHHHGCCEP VYILEPGDPP LLQQPVQTSK SGIQQIIECF
60 70 80 90 100
RSGTKQLKHI LLKDVDTIFE CKLCRSLFRG LPNLITHKKF YCPPSLQMDD
110 120 130 140 150
NLPDVNDKQS QAISDLLEAI YPRVDKREYI IKLEPIETNQ NAVFQYISRT
160 170 180 190 200
DNPAEVTESS STPEQTEVQI QETSSEQLKA VPDADTEVEE AIEPPSIETV
210 220 230 240 250
VDEAAAPTEE QPQESQADLE TSDSSDLGHQ LICCLCRKEF NSRRGVRRHI
260 270 280 290 300
RKVHKKKMEE LKKYIETRKT PNQSSKGRSK SVLVSLSRSC PVCCKSFATK
310 320 330 340 350
ANVRRHFDEV HRGLRRDSIT PDIATKPGQP LFLDSASPKK SFKTRKQKSS
360 370 380 390 400
KAEYNLTACK CLLCKRKYSS QIMLKRHMQI VHKITLSGAN SKREKGPNNT
410 420 430 440 450
ANSSEVKVEL ADSVESSPPS ITHSPQNELK GTNHSNEKKN TPATQKNKVK
460 470 480 490 500
QDSESPKSAS PSAAGGQQKT RKPKLSAGFD FKQLYCKLCK RQFTSKQNLT
510 520 530 540 550
KHIELHTDGN NIYVKFYKCP LCTYETRRKR DVIRHITVVH KKSSRYLGKI
560 570 580 590 600
TASLEIRAIK KPIDFVLNKV AKRGPSREEA KHNDSKQDGT SNSPSKKYEV
610 620 630 640 650
ADVGIEVKVT KNFSLHRCNK CGKAFAKKTY LEHHKKTHKA NATNSPEGNK
660
TKGRSTRSKA LV
Length:662
Mass (Da):74,813
Last modified:September 5, 2006 - v1
Checksum:i037359A69380D96D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC119236 mRNA. Translation: AAI19237.1.
BC119262 mRNA. Translation: AAI19263.1.
CCDSiCCDS39445.1.
RefSeqiNP_001075147.1. NM_001081678.1.
XP_006505214.1. XM_006505151.1.
XP_006505215.1. XM_006505152.2.
UniGeneiMm.393511.
Mm.84441.

Genome annotation databases

EnsembliENSMUST00000035930; ENSMUSP00000039222; ENSMUSG00000039841.
ENSMUST00000115320; ENSMUSP00000110975; ENSMUSG00000039841.
ENSMUST00000115321; ENSMUSP00000110976; ENSMUSG00000039841.
GeneIDi627049.
KEGGimmu:627049.
UCSCiuc009bcm.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC119236 mRNA. Translation: AAI19237.1.
BC119262 mRNA. Translation: AAI19263.1.
CCDSiCCDS39445.1.
RefSeqiNP_001075147.1. NM_001081678.1.
XP_006505214.1. XM_006505151.1.
XP_006505215.1. XM_006505152.2.
UniGeneiMm.393511.
Mm.84441.

3D structure databases

ProteinModelPortaliQ0VEE6.
SMRiQ0VEE6. Positions 70-96, 229-261, 288-318, 349-383, 475-509, 515-540, 609-641.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000039222.

PTM databases

iPTMnetiQ0VEE6.
PhosphoSiteiQ0VEE6.

Proteomic databases

EPDiQ0VEE6.
MaxQBiQ0VEE6.
PaxDbiQ0VEE6.
PRIDEiQ0VEE6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000035930; ENSMUSP00000039222; ENSMUSG00000039841.
ENSMUST00000115320; ENSMUSP00000110975; ENSMUSG00000039841.
ENSMUST00000115321; ENSMUSP00000110976; ENSMUSG00000039841.
GeneIDi627049.
KEGGimmu:627049.
UCSCiuc009bcm.1. mouse.

Organism-specific databases

CTDi627049.
MGIiMGI:1889334. Zfp800.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00390000008140.
HOGENOMiHOG000168334.
HOVERGENiHBG106061.
InParanoidiQ0VEE6.
OMAiRDKCCQT.
OrthoDBiEOG7F7W80.
TreeFamiTF333197.

Miscellaneous databases

PROiQ0VEE6.
SOURCEiSearch...

Gene expression databases

BgeeiQ0VEE6.
CleanExiMM_ZFP800.
ExpressionAtlasiQ0VEE6. baseline and differential.
GenevisibleiQ0VEE6. MM.

Family and domain databases

Gene3Di3.30.160.60. 1 hit.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF16622. zf-C2H2_11. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 7 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 5 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-318; SER-337; SER-420; SER-455; SER-458 AND SER-460, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Kidney, Lung and Spleen.

Entry informationi

Entry nameiZN800_MOUSE
AccessioniPrimary (citable) accession number: Q0VEE6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 5, 2006
Last modified: June 8, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.