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Protein
Submitted name:

Interferon beta 1, fibroblast

Gene

Ifnb1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation
Biological processAntiviral defenseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon beta 1, fibroblastImported
Gene namesi
Name:Ifnb1Imported
ORF Names:mCG_6581Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:107657. Ifnb1.

Subcellular locationi

  • Secreted SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500877937322 – 182Sequence analysisAdd BLAST161

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000048806.
ExpressionAtlasiQ0VE17. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000056720.

Structurei

3D structure databases

ProteinModelPortaliQ0VE17.
SMRiQ0VE17.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alpha/beta interferon family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J0RY. Eukaryota.
ENOG41113EJ. LUCA.
HOVERGENiHBG052086.
KOiK05415.
OMAiNGRLEYC.
OrthoDBiEOG091G0V76.
PhylomeDBiQ0VE17.

Family and domain databases

CDDicd00095. IFab. 1 hit.
Gene3Di1.20.1250.10. 1 hit.
InterProiView protein in InterPro
IPR009079. 4_helix_cytokine-like_core.
IPR012351. 4_helix_cytokine_core.
IPR000471. Interferon_alpha/beta/delta.
IPR015588. Interferon_beta.
PANTHERiPTHR11691. PTHR11691. 1 hit.
PTHR11691:SF56. PTHR11691:SF56. 1 hit.
PfamiView protein in Pfam
PF00143. Interferon. 1 hit.
PRINTSiPR00266. INTERFERONAB.
SMARTiView protein in SMART
SM00076. IFabd. 1 hit.
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiView protein in PROSITE
PS00252. INTERFERON_A_B_D. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0VE17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNRWILHAA FLLCFSTTAL SINYKQLQLQ ERTNIRKCQE LLEQLNGKIN
60 70 80 90 100
LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI
110 120 130 140 150
VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK
160 170 180
LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN
Length:182
Mass (Da):22,127
Last modified:September 5, 2006 - v1
Checksum:i8C4C32947FD1B917
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC119395 mRNA. Translation: AAI19396.1.
BC119397 mRNA. Translation: AAI19398.1.
CH466527 Genomic DNA. Translation: EDL30977.1.
RefSeqiNP_034640.1. NM_010510.1.
UniGeneiMm.1245.

Genome annotation databases

GeneIDi15977.
KEGGimmu:15977.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC119395 mRNA. Translation: AAI19396.1.
BC119397 mRNA. Translation: AAI19398.1.
CH466527 Genomic DNA. Translation: EDL30977.1.
RefSeqiNP_034640.1. NM_010510.1.
UniGeneiMm.1245.

3D structure databases

ProteinModelPortaliQ0VE17.
SMRiQ0VE17.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000056720.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi15977.
KEGGimmu:15977.

Organism-specific databases

CTDi3456.
MGIiMGI:107657. Ifnb1.

Phylogenomic databases

eggNOGiENOG410J0RY. Eukaryota.
ENOG41113EJ. LUCA.
HOVERGENiHBG052086.
KOiK05415.
OMAiNGRLEYC.
OrthoDBiEOG091G0V76.
PhylomeDBiQ0VE17.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000048806.
ExpressionAtlasiQ0VE17. baseline and differential.

Family and domain databases

CDDicd00095. IFab. 1 hit.
Gene3Di1.20.1250.10. 1 hit.
InterProiView protein in InterPro
IPR009079. 4_helix_cytokine-like_core.
IPR012351. 4_helix_cytokine_core.
IPR000471. Interferon_alpha/beta/delta.
IPR015588. Interferon_beta.
PANTHERiPTHR11691. PTHR11691. 1 hit.
PTHR11691:SF56. PTHR11691:SF56. 1 hit.
PfamiView protein in Pfam
PF00143. Interferon. 1 hit.
PRINTSiPR00266. INTERFERONAB.
SMARTiView protein in SMART
SM00076. IFabd. 1 hit.
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiView protein in PROSITE
PS00252. INTERFERON_A_B_D. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ0VE17_MOUSE
AccessioniPrimary (citable) accession number: Q0VE17
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: April 12, 2017
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.