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Protein
Submitted name:

Interferon beta 1, fibroblast

Gene

Ifnb1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation
Biological processAntiviral defenseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon beta 1, fibroblastImported
Gene namesi
Name:Ifnb1Imported
ORF Names:mCG_6581Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:107657 Ifnb1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501430685022 – 182Sequence analysisAdd BLAST161

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000048806

Interactioni

GO - Molecular functioni

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili105 – 125Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the alpha/beta interferon family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J0RY Eukaryota
ENOG41113EJ LUCA
HOVERGENiHBG052086
KOiK05415
OMAiCLKDRMN
OrthoDBiEOG091G0V76

Family and domain databases

CDDicd00095 IFab, 1 hit
InterProiView protein in InterPro
IPR009079 4_helix_cytokine-like_core
IPR000471 Interferon_alpha/beta/delta
IPR015588 Interferon_beta
PANTHERiPTHR11691 PTHR11691, 1 hit
PTHR11691:SF43 PTHR11691:SF43, 1 hit
PfamiView protein in Pfam
PF00143 Interferon, 1 hit
PRINTSiPR00266 INTERFERONAB
SMARTiView protein in SMART
SM00076 IFabd, 1 hit
SUPFAMiSSF47266 SSF47266, 1 hit
PROSITEiView protein in PROSITE
PS00252 INTERFERON_A_B_D, 1 hit

Sequencei

Sequence statusi: Complete.

Q0VE17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNRWILHAA FLLCFSTTAL SINYKQLQLQ ERTNIRKCQE LLEQLNGKIN
60 70 80 90 100
LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI
110 120 130 140 150
VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK
160 170 180
LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN
Length:182
Mass (Da):22,127
Last modified:September 5, 2006 - v1
Checksum:i8C4C32947FD1B917
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC119395 mRNA Translation: AAI19396.1
BC119397 mRNA Translation: AAI19398.1
CH466527 Genomic DNA Translation: EDL30977.1
RefSeqiNP_034640.1, NM_010510.1
UniGeneiMm.1245

Genome annotation databases

GeneIDi15977
KEGGimmu:15977

Similar proteinsi

Entry informationi

Entry nameiQ0VE17_MOUSE
AccessioniPrimary (citable) accession number: Q0VE17
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: April 25, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health