Q0VDI3 (CE028_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transmembrane protein C5orf28

Gene names

Name:

C5orf28

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	215 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 215	215	Transmembrane protein C5orf28		PRO_0000281921
Regions
	Transmembrane	77 – 97	21	Helical; Potential
	Transmembrane	114 – 134	21	Helical; Potential
	Transmembrane	178 – 198	21	Helical; Potential
Experimental info
	Sequence conflict	86	1	L → F in BAB15108. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q0VDI3 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 7E18288823B3BDE6	FASTA	215	24,217
	10 20 30 40 50 60 MASETEKTHA LLQTCSTESL ISSLGLGAFC LVADRLLQFS TIQQNDWLRA LSDNAVHCVI 70 80 90 100 110 120 GMWSWAVVTG IKKKTDFGEI ILAGFLASVI DVDHFFLAGS MSLKAALTLP RRPFLHCSTV 130 140 150 160 170 180 IPVVVLTLKF TMHLFKLKDS WCFLPWMLFI SWTSHHIRDG IRHGLWICPF GKTSPLPFWL 190 200 210 YVIITSSLPH ICSFVMYLTG TRQMMSSKHG VRIDV

References

[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Colon.
[2]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Lymph and PNS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK025310 mRNA. Translation: BAB15108.1. AK315466 mRNA. Translation: BAG37853.1. CH471119 Genomic DNA. Translation: EAW56061.1. BC063832 mRNA. Translation: AAH63832.1. BC013351 mRNA. Translation: AAH13351.1. BC119658 mRNA. Translation: AAI19659.1. BC119659 mRNA. Translation: AAI19660.1.
IPI	IPI00101047.
RefSeq	NP_071928.2. NM_022483.4.
UniGene	Hs.732093.
3D structure databases
ProteinModelPortal	Q0VDI3.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000380270.
Polymorphism databases
DMDM	121940485.
Proteomic databases
PaxDb	Q0VDI3.
PRIDE	Q0VDI3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000397080; ENSP00000380270; ENSG00000151881. ENST00000500337; ENSP00000426067; ENSG00000151881. ENST00000512085; ENSP00000422881; ENSG00000151881.
GeneID	64417.
KEGG	hsa:64417.
UCSC	uc003jnv.4. human.
Organism-specific databases
CTD	64417.
GeneCards	GC05M043395.
HGNC	HGNC:26139. C5orf28.
neXtProt	NX_Q0VDI3.
PharmGKB	PA162380004.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG80546.
HOGENOM	HOG000007036.
HOVERGEN	HBG097530.
InParanoid	Q0VDI3.
OMA	DNAVHCV.
PhylomeDB	Q0VDI3.
Gene expression databases
ArrayExpress	Q0VDI3.
Bgee	Q0VDI3.
CleanEx	HS_C5orf28.
Genevestigator	Q0VDI3.
Family and domain databases
InterPro	IPR026572. C5orf28-like. [Graphical view]
PANTHER	PTHR13628. PTHR13628. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	C5orf28. human.
GenomeRNAi	64417.
NextBio	66383.

Entry information

Entry name

CE028_HUMAN

Accession

Primary (citable) accession number: Q0VDI3
Secondary accession number(s): B2RDA6, Q9H6Z2

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 3, 2007
Last sequence update:	September 5, 2006
Last modified:	April 3, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.