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Q0VDI3 (CE028_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transmembrane protein C5orf28
Gene names
Name:C5orf28
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length215 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 215215Transmembrane protein C5orf28
PRO_0000281921

Regions

Transmembrane77 – 9721Helical; Potential
Transmembrane114 – 13421Helical; Potential
Transmembrane178 – 19821Helical; Potential

Experimental info

Sequence conflict861L → F in BAB15108. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q0VDI3 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 7E18288823B3BDE6

FASTA21524,217
        10         20         30         40         50         60 
MASETEKTHA LLQTCSTESL ISSLGLGAFC LVADRLLQFS TIQQNDWLRA LSDNAVHCVI 

        70         80         90        100        110        120 
GMWSWAVVTG IKKKTDFGEI ILAGFLASVI DVDHFFLAGS MSLKAALTLP RRPFLHCSTV 

       130        140        150        160        170        180 
IPVVVLTLKF TMHLFKLKDS WCFLPWMLFI SWTSHHIRDG IRHGLWICPF GKTSPLPFWL 

       190        200        210 
YVIITSSLPH ICSFVMYLTG TRQMMSSKHG VRIDV 

« Hide

References

[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Colon.
[2]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Lymph and PNS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK025310 mRNA. Translation: BAB15108.1.
AK315466 mRNA. Translation: BAG37853.1.
CH471119 Genomic DNA. Translation: EAW56061.1.
BC063832 mRNA. Translation: AAH63832.1.
BC013351 mRNA. Translation: AAH13351.1.
BC119658 mRNA. Translation: AAI19659.1.
BC119659 mRNA. Translation: AAI19660.1.
RefSeqNP_071928.2. NM_022483.4.
XP_005248390.1. XM_005248333.2.
XP_005248391.1. XM_005248334.2.
XP_005248392.1. XM_005248335.2.
XP_005248393.1. XM_005248336.2.
UniGeneHs.732093.

3D structure databases

ProteinModelPortalQ0VDI3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid122166. 1 interaction.
STRING9606.ENSP00000380270.

Polymorphism databases

DMDM121940485.

Proteomic databases

PaxDbQ0VDI3.
PRIDEQ0VDI3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000397080; ENSP00000380270; ENSG00000151881.
ENST00000500337; ENSP00000426067; ENSG00000151881.
ENST00000512085; ENSP00000422881; ENSG00000151881.
GeneID64417.
KEGGhsa:64417.
UCSCuc003jnv.4. human.

Organism-specific databases

CTD64417.
GeneCardsGC05M043395.
HGNCHGNC:26139. C5orf28.
neXtProtNX_Q0VDI3.
PharmGKBPA162380004.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG80546.
HOGENOMHOG000007036.
HOVERGENHBG097530.
InParanoidQ0VDI3.
OMADNAVHCV.
OrthoDBEOG70ZZPD.
PhylomeDBQ0VDI3.
TreeFamTF323520.

Gene expression databases

ArrayExpressQ0VDI3.
BgeeQ0VDI3.
CleanExHS_C5orf28.
GenevestigatorQ0VDI3.

Family and domain databases

InterProIPR026572. C5orf28-like.
[Graphical view]
PANTHERPTHR13628. PTHR13628. 1 hit.
ProtoNetSearch...

Other

ChiTaRSC5orf28. human.
GenomeRNAi64417.
NextBio66383.

Entry information

Entry nameCE028_HUMAN
AccessionPrimary (citable) accession number: Q0VDI3
Secondary accession number(s): B2RDA6, Q9H6Z2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: September 5, 2006
Last modified: April 16, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 5

Human chromosome 5: entries, gene names and cross-references to MIM