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Q0VD49

- Q0VD49_BOVIN

UniProt

Q0VD49 - Q0VD49_BOVIN

Protein
Submitted name:

Histone deacetylase 10

Gene

HDAC10

Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (05 Sep 2006)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. histone deacetylase activity Source: UniProtKB
    2. histone deacetylase binding Source: UniProtKB
    3. protein deacetylase activity Source: UniProtKB

    GO - Biological processi

    1. histone deacetylation Source: UniProtKB
    2. negative regulation of transcription, DNA-templated Source: UniProtKB
    3. negative regulation of transcription from RNA polymerase II promoter Source: UniProtKB
    4. protein deacetylation Source: UniProtKB

    Keywords - Molecular functioni

    HydrolaseSAAS annotation

    Enzyme and pathway databases

    ReactomeiREACT_211655. NOTCH1 Intracellular Domain Regulates Transcription.
    REACT_221028. Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants.
    REACT_225370. Constitutive Signaling by NOTCH1 PEST Domain Mutants.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Histone deacetylase 10Imported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:HDAC10Imported
    OrganismiBos taurus (Bovine)Imported
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Chromosome 5

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB
    2. histone deacetylase complex Source: UniProtKB
    3. nucleoplasm Source: UniProtKB

    Structurei

    3D structure databases

    ProteinModelPortaliQ0VD49.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00530000062809.
    HOGENOMiHOG000225183.
    HOVERGENiHBG051892.
    InParanoidiQ0VD49.
    KOiK11407.
    OMAiGLEQRCL.
    OrthoDBiEOG7992PT.
    TreeFamiTF106173.

    Family and domain databases

    Gene3Di3.40.800.20. 1 hit.
    InterProiIPR000286. His_deacetylse.
    IPR023801. His_deacetylse_dom.
    [Graphical view]
    PANTHERiPTHR10625. PTHR10625. 1 hit.
    PfamiPF00850. Hist_deacetyl. 1 hit.
    [Graphical view]
    PRINTSiPR01270. HDASUPER.

    Sequencei

    Sequence statusi: Complete.

    Q0VD49-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGTALVYHED MTATRLLWDD PECEIECPER LTTALERLQQ HGLKQRCLQL    50
    VAREASEAEL GLVHSPEYVA LLQGTQALGT RELQALSKEY DAVYLHPSTF 100
    HCARLAVGAA LQLVDAVLTG AVRNGLALVR PPGHHSQRAT ANGFCVFNNV 150
    AIAAKHAQQK HGLRRILIVD WDVHHGQGIQ YIFEDDPSVL YFSWHRYEHG 200
    HFWPCLRESD ADAVGRGRGL GFTVNLPWNQ VGMGNADYVA AFLHVLLPLA 250
    FEFDPELVLV SAGFDSAIGD PEGQMLATPE CFAHLTHLLQ VLAGGRVCAV 300
    LEGGYHLESL SQSVCMMVRA LLGDPALPLS GPMEPHGSAL ESLQCVRAAQ 350
    APHWVSLQQQ GAAPVLSPGT PCPEGRPSPL PLGEPQFKAV VTQAAAALSS 400
    LLDQLRLHPT PPVRVAVALI APDTGLALPP GVLCEEGSLP QEETQAWARP 450
    HEALAQDGAL TALGKVLYLL DRILDGQVSS GMAATPVPAA AATLDVAVRY 500
    GLSHGAQRLL CVAVGQLDRP PGLTDDGRNL WLNIGGEEAA APSMFHVSVP 550
    LPVTTGGFLS CALALVLPLA YSFQPDLVLV ALGPAHGLRD PQAALLAALL 600
    RGPAGGRVFA LVDEESTPQL ATVLARVLNG EAPPSLGPFS MAAPEDTQAL 650
    MYLRGRLEPR WKMLQVAAPH 670
    Length:670
    Mass (Da):71,493
    Last modified:September 5, 2006 - v1
    Checksum:i38DBE66CB8BBD0D0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DAAA02015043 Genomic DNA. No translation available.
    BC119835 mRNA. Translation: AAI19836.1.
    RefSeqiNP_001068928.1. NM_001075460.1.
    UniGeneiBt.24581.

    Genome annotation databases

    EnsembliENSBTAT00000014602; ENSBTAP00000014602; ENSBTAG00000011000.
    GeneIDi510654.
    KEGGibta:510654.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DAAA02015043 Genomic DNA. No translation available.
    BC119835 mRNA. Translation: AAI19836.1 .
    RefSeqi NP_001068928.1. NM_001075460.1.
    UniGenei Bt.24581.

    3D structure databases

    ProteinModelPortali Q0VD49.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSBTAT00000014602 ; ENSBTAP00000014602 ; ENSBTAG00000011000 .
    GeneIDi 510654.
    KEGGi bta:510654.

    Organism-specific databases

    CTDi 83933.

    Phylogenomic databases

    GeneTreei ENSGT00530000062809.
    HOGENOMi HOG000225183.
    HOVERGENi HBG051892.
    InParanoidi Q0VD49.
    KOi K11407.
    OMAi GLEQRCL.
    OrthoDBi EOG7992PT.
    TreeFami TF106173.

    Enzyme and pathway databases

    Reactomei REACT_211655. NOTCH1 Intracellular Domain Regulates Transcription.
    REACT_221028. Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants.
    REACT_225370. Constitutive Signaling by NOTCH1 PEST Domain Mutants.

    Miscellaneous databases

    NextBioi 20869552.

    Family and domain databases

    Gene3Di 3.40.800.20. 1 hit.
    InterProi IPR000286. His_deacetylse.
    IPR023801. His_deacetylse_dom.
    [Graphical view ]
    PANTHERi PTHR10625. PTHR10625. 1 hit.
    Pfami PF00850. Hist_deacetyl. 1 hit.
    [Graphical view ]
    PRINTSi PR01270. HDASUPER.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: L1 HerefordImported.
      Tissue: Ascending colonImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HerefordImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: HerefordImported.

    Entry informationi

    Entry nameiQ0VD49_BOVIN
    AccessioniPrimary (citable) accession number: Q0VD49
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 5, 2006
    Last sequence update: September 5, 2006
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3