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Protein

C-type lectin domain family 1 member A

Gene

CLEC1A

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandLectin

Names & Taxonomyi

Protein namesi
Recommended name:
C-type lectin domain family 1 member A
Alternative name(s):
C-type lectin-like receptor 1
Short name:
CLEC-1
Gene namesi
Name:CLEC1A
Synonyms:CLEC1
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 5

Organism-specific databases

VGNCiVGNC:27427 CLEC1A

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 52CytoplasmicSequence analysisAdd BLAST52
Transmembranei53 – 73Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini74 – 278ExtracellularSequence analysisAdd BLAST205

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003135771 – 278C-type lectin domain family 1 member AAdd BLAST278

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi95N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi165 ↔ 257PROSITE-ProRule annotation
Glycosylationi169N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi236 ↔ 249PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ0VCS6
PRIDEiQ0VCS6

Expressioni

Gene expression databases

BgeeiENSBTAG00000030424

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000019328

Structurei

3D structure databases

ProteinModelPortaliQ0VCS6
SMRiQ0VCS6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini144 – 258C-type lectinPROSITE-ProRule annotationAdd BLAST115

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4297 Eukaryota
ENOG410XPJ1 LUCA
GeneTreeiENSGT00700000104266
HOGENOMiHOG000111777
HOVERGENiHBG103475
InParanoidiQ0VCS6
KOiK10069
OMAiFAMPQSY
OrthoDBiEOG091G0K57
TreeFamiTF336674

Family and domain databases

CDDicd03593 CLECT_NK_receptors_like, 1 hit
Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR001304 C-type_lectin-like
IPR016186 C-type_lectin-like/link_sf
IPR016187 CTDL_fold
IPR033992 NKR-like_CTLD
PfamiView protein in Pfam
PF00059 Lectin_C, 1 hit
SMARTiView protein in SMART
SM00034 CLECT, 1 hit
SUPFAMiSSF56436 SSF56436, 1 hit
PROSITEiView protein in PROSITE
PS50041 C_TYPE_LECTIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q0VCS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLAKYSSTRD MLDADGDTTM SLHSQASATS QRPELGHTEH QRPSSAWRPV
60 70 80 90 100
ALILLTLCLV LLIGLAALGL VFFQFYQLSN TQQDSILQKE EKLGNLSRQL
110 120 130 140 150
QSLRTQNRKL AETLHHVAEK LCRELYNKTG EHRCSPCPEK WKWHGDKCYQ
160 170 180 190 200
FYKESKSWQG CEYFCIAENS TMLKINTQEV LEFAMPQSYS EFFYSYWTGL
210 220 230 240 250
SRNSSGKAWL WMDGTPYSSE LFDVMIDLTS LRSRDCVTIL NGKAFSKDCR
260 270
ELRRCACEKA AAMVKVQSLH EPLSRRWR
Length:278
Mass (Da):32,094
Last modified:September 5, 2006 - v1
Checksum:iB31FA5B249463283
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120028 mRNA Translation: AAI20029.1
RefSeqiNP_001069549.1, NM_001076081.1
UniGeneiBt.37940

Genome annotation databases

EnsembliENSBTAT00000019328; ENSBTAP00000019328; ENSBTAG00000030424
GeneIDi536944
KEGGibta:536944

Similar proteinsi

Entry informationi

Entry nameiCLC1A_BOVIN
AccessioniPrimary (citable) accession number: Q0VCS6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 5, 2006
Last modified: March 28, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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