ID   KAD4_BOVIN              Reviewed;         223 AA.
AC   Q0VCP1;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   16-JUN-2009, entry version 24.
DE   RecName: Full=Adenylate kinase isoenzyme 4, mitochondrial;
DE            EC=2.7.4.3;
DE   AltName: Full=Adenylate kinase 3-like;
DE   AltName: Full=ATP-AMP transphosphorylase;
GN   Name=AK3L1; Synonyms=AK4;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal pons;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the reversible transfer of the terminal
CC       phosphate group between ATP and AMP. May also be active with GTP
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + AMP = 2 ADP.
CC   -!- SUBUNIT: Monomer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix (By similarity).
CC   -!- SIMILARITY: Belongs to the adenylate kinase family.
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DR   EMBL; BC120077; AAI20078.1; -; mRNA.
DR   IPI; IPI00712062; -.
DR   RefSeq; NP_001071401.1; -.
DR   UniGene; Bt.63820; -.
DR   SMR; Q0VCP1; 4-223.
DR   Ensembl; ENSBTAG00000030674; Bos taurus.
DR   GeneID; 517063; -.
DR   KEGG; bta:517063; -.
DR   HOVERGEN; Q0VCP1; -.
DR   OMA; Q0VCP1; HSFSGTE.
DR   BRENDA; 2.7.4.3; 251.
DR   GO; GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
DR   GO; GO:0004017; F:adenylate kinase activity; IEA:EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006139; P:nucleobase, nucleoside, nucleotide and nucl...; IEA:InterPro.
DR   InterPro; IPR006259; Adenyl_kin_sub.
DR   InterPro; IPR000850; Adenylate_kin.
DR   InterPro; IPR007862; Adenylate_kinase_Znf_lid.
DR   PANTHER; PTHR23359; Adenylate_kin; 1.
DR   Pfam; PF00406; ADK; 1.
DR   Pfam; PF05191; ADK_lid; 1.
DR   PRINTS; PR00094; ADENYLTKNASE.
DR   ProDom; PD000657; Adenylate_kin; 1.
DR   TIGRFAMs; TIGR01351; adk; 1.
DR   PROSITE; PS00113; ADENYLATE_KINASE; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; GTP-binding; Kinase; Mitochondrion; Nucleotide-binding;
KW   Transferase.
FT   CHAIN         1    223       Adenylate kinase isoenzyme 4,
FT                                mitochondrial.
FT                                /FTId=PRO_0000262883.
FT   NP_BIND      12     20       ATP (By similarity).
FT   NP_BIND      89     96       AMP (By similarity).
FT   BINDING      36     36       AMP (By similarity).
SQ   SEQUENCE   223 AA;  25348 MW;  4CCA67455279F3AF CRC64;
     MASKLLRAVI LGPPGSGKGT VCQRIAQNFG LQHLSSGHFL RENIKANTEV GDMAKQYIEK
     GLLVPDHVIT RLMLLELENR RGEHWLLDGF PRTLVQAEAL DRLCDLDLVI TLNIPFETLK
     DRLSRRWIHP PSGRVYNLDF NPPHVHGMDD VTGEPLVQQE DDKPEAVAAR LRQYKDVAKP
     VIELYKSRGV LHQFSGTETN KIWPYVYTLF SNKITPVQSK EAY
//