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Protein

Protein mago nashi homolog 2

Gene

MAGOHB

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in mRNA splicing and in the nonsense-mediated decay (NMD) pathway.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-binding
Biological processmRNA processing, mRNA splicing, mRNA transport, Transport

Enzyme and pathway databases

ReactomeiR-BTA-109688 Cleavage of Growing Transcript in the Termination Region
R-BTA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript
R-BTA-72163 mRNA Splicing - Major Pathway
R-BTA-72187 mRNA 3'-end processing

Names & Taxonomyi

Protein namesi
Recommended name:
Protein mago nashi homolog 2
Gene namesi
Name:MAGOHB
Synonyms:MAGOH2
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00003233802 – 148Protein mago nashi homolog 2Add BLAST147

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ0VC92
PRIDEiQ0VC92

Expressioni

Gene expression databases

BgeeiENSBTAG00000019235

Interactioni

Subunit structurei

Interacts with RBM8A and is part of the exon junction complex (EJC).By similarity

Protein-protein interaction databases

IntActiQ0VC92, 2 interactors
STRINGi9913.ENSBTAP00000025615

Structurei

3D structure databases

ProteinModelPortaliQ0VC92
SMRiQ0VC92
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mago nashi family.Curated

Phylogenomic databases

eggNOGiKOG3392 Eukaryota
ENOG4111FJ7 LUCA
GeneTreeiENSGT00390000003156
HOGENOMiHOG000207428
HOVERGENiHBG004353
InParanoidiQ0VC92
KOiK12877
OMAiEFDFRVV
OrthoDBiEOG091G0UKA
TreeFamiTF300128

Family and domain databases

CDDicd11295 Mago_nashi, 1 hit
Gene3Di3.30.1560.10, 1 hit
InterProiView protein in InterPro
IPR004023 Mago_nashi
IPR036605 Mago_nashi_sf
PANTHERiPTHR12638 PTHR12638, 1 hit
PfamiView protein in Pfam
PF02792 Mago_nashi, 1 hit
SUPFAMiSSF89817 SSF89817, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q0VC92-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMASDFYLR YYVGHKGKFG HEFLEFEFRP DGKLRYANNS NYKNDVMIRK
60 70 80 90 100
EAYVHKSVME ELKRIIDDSE ITKEDDALWP PPDRVGRQEL EIVIGDEHIS
110 120 130 140
FTTSKIGSLI DVNQSKDPEG LRVFYYLVQD LKCLVFSLIG LHFKIKPI
Length:148
Mass (Da):17,308
Last modified:September 5, 2006 - v1
Checksum:i0DDD3FD3ADD09E28
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120291 mRNA Translation: AAI20292.1
RefSeqiNP_001069720.1, NM_001076252.1
UniGeneiBt.22385

Genome annotation databases

EnsembliENSBTAT00000025615; ENSBTAP00000025615; ENSBTAG00000019235
GeneIDi541013
KEGGibta:541013

Similar proteinsi

Entry informationi

Entry nameiMGN2_BOVIN
AccessioniPrimary (citable) accession number: Q0VC92
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: September 5, 2006
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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