Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Adenosine deaminase-like protein

Gene

ADAL

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Putative nucleoside deaminase. May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity).By similarity

Cofactori

Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi23Zinc; catalyticBy similarity1
Metal bindingi25Zinc; catalyticBy similarity1
Binding sitei25SubstrateBy similarity1
Binding sitei180Substrate; via amide nitrogen and carbonyl oxygenBy similarity1
Metal bindingi207Zinc; catalyticBy similarity1
Active sitei210Proton donorBy similarity1
Sitei231Important for catalytic activityBy similarity1
Metal bindingi292Zinc; catalyticBy similarity1
Binding sitei293SubstrateBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Nucleotide metabolism

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Adenosine deaminase-like protein (EC:3.5.4.-)
Gene namesi
Name:ADAL
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002850891 – 351Adenosine deaminase-like proteinAdd BLAST351

Proteomic databases

PaxDbiQ0VC13.
PRIDEiQ0VC13.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000019248.

Structurei

3D structure databases

ProteinModelPortaliQ0VC13.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1097. Eukaryota.
COG1816. LUCA.
HOGENOMiHOG000205847.
HOVERGENiHBG055638.
InParanoidiQ0VC13.

Family and domain databases

InterProiIPR001365. A/AMP_deaminase_dom.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF00962. A_deaminase. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0VC13-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMEAEEQPWK TTFYSKLPKV ELHAHLNGSI SSNTIRKLIA KKPDLKIHDQ
60 70 80 90 100
MTMIDKGEKR TLEECLQMFQ IIHLLTTTPE DVLMVTKDVI KEFADDGVKY
110 120 130 140 150
LELRSTPRGE DATGMTKKTY VESILEGIKQ SKEENVDIDV RYLISIDRRG
160 170 180 190 200
GSSAAKEAVK LAEEFFLSAE DTVLGLDLSG DPSAGQAKDF LEPLLEAKKS
210 220 230 240 250
GLKLALHLSE IPNQKTETQV LLNLFPDRIG HGTFLSSSEE GSPDLVDFVR
260 270 280 290 300
QHQIPLELCL TSNVKSQTVP AYDQHHFGFW YSVAHPAVIC TDDKGVFATR
310 320 330 340 350
LSQEYQLVAE TFHLTQSQVW DLSYESISYI FASDSTKADL RKKWSHLKPH

F
Length:351
Mass (Da):39,646
Last modified:September 5, 2006 - v1
Checksum:i258E442F7867F481
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120402 mRNA. Translation: AAI20403.1.
RefSeqiNP_001069045.1. NM_001075577.1.
UniGeneiBt.28556.

Genome annotation databases

GeneIDi512667.
KEGGibta:512667.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120402 mRNA. Translation: AAI20403.1.
RefSeqiNP_001069045.1. NM_001075577.1.
UniGeneiBt.28556.

3D structure databases

ProteinModelPortaliQ0VC13.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000019248.

Proteomic databases

PaxDbiQ0VC13.
PRIDEiQ0VC13.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi512667.
KEGGibta:512667.

Organism-specific databases

CTDi161823.

Phylogenomic databases

eggNOGiKOG1097. Eukaryota.
COG1816. LUCA.
HOGENOMiHOG000205847.
HOVERGENiHBG055638.
InParanoidiQ0VC13.

Family and domain databases

InterProiIPR001365. A/AMP_deaminase_dom.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF00962. A_deaminase. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiADAL_BOVIN
AccessioniPrimary (citable) accession number: Q0VC13
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: September 5, 2006
Last modified: June 8, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.