Bdkrb1

Functionⁱ

GO - Molecular functionⁱ

bradykinin receptor activity Source: Ensembl
peptide binding Source: Ensembl

Complete GO annotation...

GO - Biological processⁱ

cell migration Source: Ensembl
inflammatory response Source: Ensembl
negative regulation of blood pressure Source: Ensembl
negative regulation of cell growth Source: Ensembl
negative regulation of protein phosphorylation Source: Ensembl
positive regulation of leukocyte migration Source: Ensembl
positive regulation of release of sequestered calcium ion into cytosol Source: Ensembl
protein kinase C-activating G-protein coupled receptor signaling pathway Source: Ensembl
response to lipopolysaccharide Source: Ensembl
response to mechanical stimulus Source: InterPro
sensory perception of pain Source: Ensembl

Complete GO annotation...

Keywordsⁱ

Molecular function	ReceptorImported

Molecular function

ReceptorImported

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Bradykinin receptor, beta 1Imported Submitted name: MCG1159Imported
Gene namesⁱ	Name:Bdkrb1Imported ORF Names:mCG_1159Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus

Organism-specific databases

MGIⁱ	MGI:88144. Bdkrb1.

Subcellular locationⁱ

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	42 – 65	HelicalSequence analysisAdd BLAST	24
Transmembraneⁱ	77 – 100	HelicalSequence analysisAdd BLAST	24
Transmembraneⁱ	120 – 140	HelicalSequence analysisAdd BLAST	21
Transmembraneⁱ	161 – 182	HelicalSequence analysisAdd BLAST	22
Transmembraneⁱ	215 – 236	HelicalSequence analysisAdd BLAST	22
Transmembraneⁱ	257 – 279	HelicalSequence analysisAdd BLAST	23
Transmembraneⁱ	299 – 322	HelicalSequence analysisAdd BLAST	24

GO - Cellular componentⁱ

integral component of membrane Source: UniProtKB-KW
neuron projection Source: Ensembl
plasma membrane Source: Ensembl

Complete GO annotation...

Keywords - Cellular componentⁱ

Membrane

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000041347.

Bgeeⁱ

ENSMUSG00000041347.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	53 – 319	G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST		267

Keywords - Domainⁱ

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG3656. Eukaryota. ENOG410XRW9. LUCA.
HOVERGENⁱ	HBG103183.
KEGG Orthology (KO) More...KOⁱ	K03915.
OMAⁱ	FNCHILA.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0D52.

Family and domain databases

InterProⁱ	View protein in InterPro IPR001186. Brdyknn_1_rcpt. IPR000496. Brdyknn_rcpt. IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001. 7tm_1. 1 hit.
PRINTSⁱ	PR00425. BRADYKININR. PR00993. BRADYKINNB1R. PR00237. GPCRRHODOPSN.
PROSITEⁱ	View protein in PROSITE PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q0VBD7-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MASQASLKLQ PSNQSQQAPP NITSCEGAPE AWDLLCRVLP GFVITVCFFG 
        60         70         80         90        100
LLGNLLVLSF FLLPWRRWWQ QRRQRLTIAE IYLANLAASD LVFVLGLPFW 
       110        120        130        140        150
AENVGNRFNW PFGSDLCRVV SGVIKANLFI SIFLVVAISQ DRYRLLVYPM 
       160        170        180        190        200
TSWGNRRRRQ AQVTCLLIWV AGGLLSTPTF LLRSVKVVPD LNISACILLF 
       210        220        230        240        250
PHEAWHFVRM VELNVLGFLL PLAAILYFNF HILASLRGQK EASRTRCGGP 
       260        270        280        290        300
KDSKTMGLIL TLVASFLVCW APYHFFAFLD FLVQVRVIQD CFWKELTDLG 
       310        320        330 
LQLANFFAFV NSCLNPLIYV FAGRLFKTRV LGTL

Length:334

Mass (Da):37,886

Last modified:September 5, 2006 - v1

Checksum:ⁱ77C806203AC5C6CC

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC120684 mRNA. Translation: AAI20685.1. CH466549 Genomic DNA. Translation: EDL18757.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_031565.1. NM_007539.3.
UniGeneⁱ	Mm.377078.

Genome annotation databases

GeneIDⁱ	12061.
KEGGⁱ	mmu:12061.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC120684 mRNA. Translation: AAI20685.1. CH466549 Genomic DNA. Translation: EDL18757.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_031565.1. NM_007539.3.
UniGeneⁱ	Mm.377078.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	12061.
KEGGⁱ	mmu:12061.

Organism-specific databases

CTDⁱ	623.
MGIⁱ	MGI:88144. Bdkrb1.

Phylogenomic databases

eggNOGⁱ	KOG3656. Eukaryota. ENOG410XRW9. LUCA.
HOVERGENⁱ	HBG103183.
KEGG Orthology (KO) More...KOⁱ	K03915.
OMAⁱ	FNCHILA.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0D52.

Miscellaneous databases

SOURCEⁱ	Search...

SOURCEⁱ

Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000041347.

Bgeeⁱ

ENSMUSG00000041347.

Family and domain databases

InterProⁱ	View protein in InterPro IPR001186. Brdyknn_1_rcpt. IPR000496. Brdyknn_rcpt. IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001. 7tm_1. 1 hit.
PRINTSⁱ	PR00425. BRADYKININR. PR00993. BRADYKINNB1R. PR00237. GPCRRHODOPSN.
PROSITEⁱ	View protein in PROSITE PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q0VBD7_MOUSE
Accessionⁱ	Q0VBD7Primary (citable) accession number: Q0VBD7
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	September 5, 2006
	Last sequence update:	September 5, 2006
	Last modified:	July 5, 2017
	This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

UniProtKB - Q0VBD7 (Q0VBD7_MOUSE)

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Bradykinin receptor, beta 1

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Organism-specific databases

Subcellular locationⁱ

Topology

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

Expressionⁱ

Gene expression databases

Family & Domainsⁱ

Domains and Repeats

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q0VBD7 (Q0VBD7_MOUSE)

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Bradykinin receptor, beta 1

Bdkrb1

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Expressionⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ