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Protein

C-C motif chemokine

Gene

Ccl1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation
Biological processChemotaxisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
C-C motif chemokineUniRule annotation
Gene namesi
Name:Ccl1Imported
ORF Names:mCG_8193Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98258. Ccl1.

Subcellular locationi

  • Secreted UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

SecretedUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23UniRule annotationAdd BLAST23
ChainiPRO_500903143924 – 92C-C motif chemokineUniRule annotationAdd BLAST69

Expressioni

Gene expression databases

BgeeiENSMUSG00000020702.
ExpressionAtlasiQ0VB35. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000103824.

Structurei

3D structure databases

ProteinModelPortaliQ0VB35.
SMRiQ0VB35.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 89SCYInterPro annotationAdd BLAST60

Sequence similaritiesi

Belongs to the intercrine beta (chemokine CC) family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410J85U. Eukaryota.
ENOG4111AVY. LUCA.
HOVERGENiHBG098128.
KOiK05514.
OMAiMQIITTA.
OrthoDBiEOG091G15E8.

Family and domain databases

InterProiView protein in InterPro
IPR000827. Chemokine_CC_CS.
IPR001811. Chemokine_IL8-like_dom.
PfamiView protein in Pfam
PF00048. IL8. 1 hit.
SMARTiView protein in SMART
SM00199. SCY. 1 hit.
SUPFAMiSSF54117. SSF54117. 1 hit.
PROSITEiView protein in PROSITE
PS00472. SMALL_CYTOKINES_CC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0VB35-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPTAMALMC LLLAAVWIQD VDSKSMLTVS NSCCLNTLKK ELPLKFIQCY
60 70 80 90
RKMGSSCPDP PAVVFRLNKG RESCASTNKT WVQNHLKKVN PC
Length:92
Mass (Da):10,276
Last modified:February 5, 2008 - v1
Checksum:iBF057DEAA1771096
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120806 mRNA. Translation: AAI20807.1.
CH466556 Genomic DNA. Translation: EDL15663.1.
RefSeqiNP_035459.1. NM_011329.3.
UniGeneiMm.1283.

Genome annotation databases

GeneIDi20290.
KEGGimmu:20290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120806 mRNA. Translation: AAI20807.1.
CH466556 Genomic DNA. Translation: EDL15663.1.
RefSeqiNP_035459.1. NM_011329.3.
UniGeneiMm.1283.

3D structure databases

ProteinModelPortaliQ0VB35.
SMRiQ0VB35.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000103824.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi20290.
KEGGimmu:20290.

Organism-specific databases

CTDi6346.
MGIiMGI:98258. Ccl1.

Phylogenomic databases

eggNOGiENOG410J85U. Eukaryota.
ENOG4111AVY. LUCA.
HOVERGENiHBG098128.
KOiK05514.
OMAiMQIITTA.
OrthoDBiEOG091G15E8.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020702.
ExpressionAtlasiQ0VB35. baseline and differential.

Family and domain databases

InterProiView protein in InterPro
IPR000827. Chemokine_CC_CS.
IPR001811. Chemokine_IL8-like_dom.
PfamiView protein in Pfam
PF00048. IL8. 1 hit.
SMARTiView protein in SMART
SM00199. SCY. 1 hit.
SUPFAMiSSF54117. SSF54117. 1 hit.
PROSITEiView protein in PROSITE
PS00472. SMALL_CYTOKINES_CC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ0VB35_MOUSE
AccessioniPrimary (citable) accession number: Q0VB35
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: April 12, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.