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Protein
Submitted name:

RAS protein activator like 2

Gene

Rasal2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGTPase activationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
RAS protein activator like 2Imported
Gene namesi
Name:Rasal2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2443881 Rasal2

PTM / Processingi

Proteomic databases

PRIDEiQ0VAV5

Expressioni

Gene expression databases

GenevisibleiQ0VAV5 MM

Interactioni

Protein-protein interaction databases

IntActiQ0VAV5, 1 interactor
MINTiQ0VAV5

Structurei

3D structure databases

ProteinModelPortaliQ0VAV5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 287PHInterPro annotationAdd BLAST231
Domaini456 – 648Ras-GAPInterPro annotationAdd BLAST193

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1095 – 1181Sequence analysisAdd BLAST87

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3508 Eukaryota
ENOG410XPU1 LUCA
HOGENOMiHOG000231979
HOVERGENiHBG006492
KOiK17633

Family and domain databases

Gene3Di2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR021887 DUF3498
IPR001849 PH_domain
IPR023152 RasGAP_CS
IPR001936 RasGAP_dom
IPR008936 Rho_GTPase_activation_prot
PfamiView protein in Pfam
PF00168 C2, 1 hit
PF12004 DUF3498, 1 hit
PF00616 RasGAP, 1 hit
SMARTiView protein in SMART
SM00239 C2, 1 hit
SM00233 PH, 1 hit
SM00323 RasGAP, 1 hit
SUPFAMiSSF48350 SSF48350, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
PS00509 RAS_GTPASE_ACTIV_1, 1 hit
PS50018 RAS_GTPASE_ACTIV_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q0VAV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFTGLESDSP LPPEDLDAVV PVSGAVAGGM LDRILLESVC QQQSWVRVFD
60 70 80 90 100
VKGPPTHRLS CGQSPYTETT SWERKYCILT DSQLVLLNKE KEMPVEGQDQ
110 120 130 140 150
QTDSTKGRCL RRTVSVPSEG QFPEYPQEGT TKLEVPAERS PRRRSISGTS
160 170 180 190 200
TSEKPNSMDT ANTSPFKVPG FFSKRLKGSI KRTKSQSKLD RNTSFRLPSL
210 220 230 240 250
RNADDRSRGL PKLKESRSHG SLLSPCSAVE CLDLGRGEPV SVKPLHSSIL
260 270 280 290 300
GQDFCFEVTY LSGSKCFSCS SASERDKWME NLRRTVQPNK DNCRRAENVL
310 320 330 340 350
RLWIIEAKDL APKKKYFCEL CLDDTLFART TSKTKADNIF WGEHFEFYSL
360 370 380 390 400
PPLHSITVHI YKDVEKKKKK DKNNYVGLVN IPTASVTGRQ FVEKWYPVST
410 420 430 440 450
PTPNKGKTGG PSIRIKSRFQ TITILPMEQY KEFAEFITSN YTMLCSVLEP
460 470 480 490 500
VISVRNKEEL ACALVHILQS TGRAKDFLTD LVMSEVDRCG EHDVLIFREN
510 520 530 540 550
TIATKSIEEY LKLVGQQYLH DALGEFIKAL YESDENCEVD PSKCSSSELM
560 570 580 590 600
DHQSNLKMCC ELAFCKIINS YCVFPRELKE VFASWKQQCL NRGKQDISER
610 620 630 640 650
LISASLFLRF LCPAIMSPSL FNLMQEYPDD RTSRTLTLIA KVIQNLANFA
660 670 680 690 700
KFGNKEEYMA FMNDFLEHEW GGMKRFLLEI SNPDTISNTP GFDGYIDLGR
710 720 730 740 750
ELSVLHSLLW EVVSQLDKGE NSFLQATVAK LGPLPRVLAD ITKSLTNPTP
760 770 780 790 800
IQQQLRRFAE HSSSPNVSGS LSSGLQRICE DPTDSDLHKL KSPSQDNTDS
810 820 830 840 850
YFRGKTLLLV QQASSQSMTY SEKDEKENSL PNGRSISLMD LQDTHAAQAE
860 870 880 890 900
HASVMLDVPM RLAGSQLSIT QVASIKQLRE TQSTPQSAPQ VRRPLHPALN
910 920 930 940 950
QPGSLQPLSF QNPVYHLNNP VPAMPKASAD SSLENLSTAS SRSQSNSEDF
960 970 980 990 1000
KLSGPSNSSM EDFTKRSSHS EDFSRRHTVP DRHIPLALPR QNSTGQSQIR
1010 1020 1030 1040 1050
KLDHSGLGAR AKAPPSLPHS ASLRSTGSMS VASAALMAEP VQNGSRSRQQ
1060 1070 1080 1090 1100
SSSSRESPVP KVRAIQRQQT QQVQSPVDSA TMSPVERTAA WVLNNGQYEE
1110 1120 1130 1140 1150
DVEETEQNQD EAKHAEKYEQ EITKLKERLR VSSRRLEEYE RRLLVQEQQM
1160 1170 1180 1190 1200
QKLLLEYKAR LEDSEERLRR QQEEKDSQMK SIISRLMAVE EELKKDHAEM
1210 1220 1230 1240 1250
QAVIDAKQKI IDAQEKRIVS LDSANTRLMS ALTQVKERYS MQVRNGISPT
1260
NPTKLSITEN GEFKNSSC
Length:1,268
Mass (Da):142,714
Last modified:September 5, 2006 - v1
Checksum:iB770CB1F05C0CCC0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120902 mRNA Translation: AAI20903.1
RefSeqiNP_808312.3, NM_177644.5
UniGeneiMm.235028
Mm.439484

Genome annotation databases

GeneIDi226525
KEGGimmu:226525

Similar proteinsi

Entry informationi

Entry nameiQ0VAV5_MOUSE
AccessioniPrimary (citable) accession number: Q0VAV5
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: March 28, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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