Q0VAN4 (Q0VAN4_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
C1q and tumor necrosis factor related protein 3 EMBL AAI20991.1

Submitted name:
CTRP3 variant B EMBL ABY86417.1
Submitted name:
Uncharacterized protein Ensembl ENSP00000371497
Submitted name:
cDNA FLJ58190, highly similar to Homo sapiens C1q and tumor necrosis factor related protein 3 (C1QTNF3), transcript variant 2, mRNA EMBL BAG58744.1
Submitted name:
cDNA, FLJ78820, highly similar to Homo sapiens C1q and tumor necrosis factor related protein 3 (C1QTNF3), transcript variant 2, mRNA EMBL BAH14292.1

Gene names

Name:

C1QTNF3 Ensembl ENSP00000371497 EMBL AAI20991.1

Organism

Homo sapiens (Human) EMBL AAI20991.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	319 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 C1q domain. SAAS SAAS008160

Ontologies

Keywords
Cellular component	Secreted SAAS SAAS008160
Domain	Collagen SAAS SAAS008160
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	collagen Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0VAN4 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: EC12962E5B726F00	FASTA	319	35,183
	10 20 30 40 50 60 MLWRQLIYWQ LLALFFLPFC LCQDEYMEVS GRTNKVVARI VQSHQQTGRS GSRREKVRER 70 80 90 100 110 120 SHPKTGTVDN NTSTDLKSLR PDELPHPEVD DLAQITTFWG QSPQTGGLPP DCSKCCHGDY 130 140 150 160 170 180 SFRGYQGPPG PPGPPGIPGN HGNNGNNGAT GHEGAKGEKG DKGDLGPRGE RGQHGPKGEK 190 200 210 220 230 240 GYPGIPPELQ IAFMASLATH FSNQNSGIIF SSVETNIGNF FDVMTGRFGA PVSGVYFFTF 250 260 270 280 290 300 SMMKHEDVEE VYVYLMHNGN TVFSMYSYEM KGKSDTSSNH AVLKLAKGDE VWLRMGNGAL 310 HGDHQRFSTF AGFLLFETK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and comparative analysis of human chromosome 5." Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S. , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M. Nature 431:268-274(2004) [PubMed: 15372022] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"C1q/TNF-related protein-3 (CTRP3), a novel adipokine that regulates hepatic glucose output." Peterson J.M., Wei Z., Wong G.W. J. Biol. Chem. 285:39691-39701(2010) [PubMed: 20952387] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: PCR rescued clones EMBL AAI20991.1.
[4]	"NEDO human cDNA sequencing project." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Cerebellum EMBL BAH14292.1.
[5]	"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Substantia nigra EMBL BAG58744.1.
[6]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC139783 Genomic DNA. No translation available. AC139792 Genomic DNA. No translation available. BC120990 mRNA. Translation: AAI20991.1. EU399232 mRNA. Translation: ABY86417.1. AK295968 mRNA. Translation: BAG58744.1. AK315921 mRNA. Translation: BAH14292.1.
IPI	IPI00643667.
RefSeq	NP_112207.1. NM_030945.3. NP_852100.3. NM_181435.5.
UniGene	Hs.171929.
3D structure databases
ProteinModelPortal	Q0VAN4.
SMR	Q0VAN4. Positions 130-164, 190-317.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0VAN4.
Proteomic databases
PRIDE	Q0VAN4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000382065; ENSP00000371497; ENSG00000082196.
GeneID	114899.
KEGG	hsa:114899.
UCSC	uc003jio.1. human.
Organism-specific databases
CTD	114899.
HGNC	HGNC:14326. C1QTNF3.
PharmGKB	PA25630.
GenAtlas	Search...
Phylogenomic databases
GeneTree	ENSGT00560000076704.
HOVERGEN	HBG108220.
Gene expression databases
ArrayExpress	Q0VAN4.
Bgee	Q0VAN4.
Family and domain databases
InterPro	IPR001073. C1q. IPR008160. Collagen. IPR008983. Tumour_necrosis_fac-like. [Graphical view]
Gene3D	G3DSA:2.60.120.40. Tumour_necrosis_fac-like. 1 hit.
Pfam	PF00386. C1q. 1 hit. PF01391. Collagen. 1 hit. [Graphical view]
PRINTS	PR00007. COMPLEMNTC1Q.
SMART	SM00110. C1Q. 1 hit. [Graphical view]
SUPFAM	SSF49842. TNF_like. 1 hit.
PROSITE	PS50871. C1Q. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	79406.

Entry information

Entry name

Q0VAN4_HUMAN

Accession

Primary (citable) accession number: Q0VAN4

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.