ID   SYTC2_XENTR             Reviewed;         814 AA.
AC   Q0V9S0;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   16-JUN-2009, entry version 24.
DE   RecName: Full=Probable threonyl-tRNA synthetase 2, cytoplasmic;
DE            EC=6.1.1.3;
DE   AltName: Full=Threonine--tRNA ligase;
DE            Short=ThrRS;
DE   AltName: Full=Threonyl-tRNA synthetase-like protein 2;
GN   Name=tarsl2;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;
OC   Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: ATP + L-threonine + tRNA(Thr) = AMP +
CC       diphosphate + L-threonyl-tRNA(Thr).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase
CC       family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; BC121417; AAI21418.1; -; mRNA.
DR   RefSeq; NP_001096223.1; -.
DR   UniGene; Str.31543; -.
DR   GeneID; 100124774; -.
DR   KEGG; xtr:100124774; -.
DR   Xenbase; XB-FEAT-5954361; tarsl2.
DR   HOVERGEN; Q0V9S0; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004829; F:threonine-tRNA ligase activity; IEA:EC.
DR   GO; GO:0006435; P:threonyl-tRNA aminoacylation; IEA:InterPro.
DR   InterPro; IPR002314; aa-tRNA-synt_IIb_cons-reg.
DR   InterPro; IPR006195; aa-tRNA-synth_II_cons-reg.
DR   InterPro; IPR004154; Anticodon_bd.
DR   InterPro; IPR012675; b-grasp_ferredoxin-like.
DR   InterPro; IPR004095; TGS.
DR   InterPro; IPR002320; Thr-tRNA-synth_IIa.
DR   InterPro; IPR018158; Thr-tRNA-synth_IIa_cons-reg.
DR   InterPro; IPR012947; tRNA_SAD.
DR   Gene3D; G3DSA:3.40.50.800; Anticodon_bd; 1.
DR   Gene3D; G3DSA:3.10.20.30; Ferredoxin_fold; 1.
DR   Pfam; PF03129; HGTP_anticodon; 1.
DR   Pfam; PF02824; TGS; 1.
DR   Pfam; PF00587; tRNA-synt_2b; 1.
DR   Pfam; PF07973; tRNA_SAD; 1.
DR   PRINTS; PR01047; TRNASYNTHTHR.
DR   TIGRFAMs; TIGR00418; thrS; 1.
DR   PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE   2: Evidence at transcript level;
KW   Aminoacyl-tRNA synthetase; ATP-binding; Coiled coil; Cytoplasm;
KW   Ligase; Nucleotide-binding; Protein biosynthesis.
FT   CHAIN         1    814       Probable threonyl-tRNA synthetase 2,
FT                                cytoplasmic.
FT                                /FTId=PRO_0000333830.
FT   COILED        2     72       Potential.
SQ   SEQUENCE   814 AA;  93328 MW;  97A63139DAEE7562 CRC64;
     MAAHIAQRLT VQEQEIRRLN EEIGRLLELG LQGSVEHSPN PVLEQLRAEN EKLKYRISHL
     QRSLREEQER ARPGQYGEPG LKDAAPVEEP KQQNNKAKEK GQATKGENSV GGKPSACEGN
     KKNEKKAGKE VDGHKQEGPC APGFIKDRLA LYETLKNEHD ALLAARAAHQ SKPIKITLAD
     GKQVDGESWK TTPYQVAIGI SKGLADNVVI AKVNNELWDL DRPLEQDSNV ELLKFDSEEA
     QAVYWHSSAH ILGETMENFY GGCLCYGPPI ENGFYYDMYL DGRGVSSNEF PSLENMCKAI
     IKEKQPFERL EVSKDLLLEM FKYNKFKCRI LNEKVDTPTT TVYRCGPLID LCRGPHVRHT
     GKIKTLKIYK NSSTYWEGRA DMETLQRIYG ISFPDSKLMK EWEQFQEEAK NRDHRKIGRD
     QELFFFHDLS PGSCFFLPRG AHIYNTLTDF IKGEYQIRNF TEVASPNIYN SKLWEMSGHW
     QHYSENMFSF EVEKETFALK PMNCPGHCLM FGHRPRSWRE LPLRFADFGV LHRNELSGTL
     SGLTRVRRFQ QDDAHIFCTM DQIQEEMNGC LQFLQSVYKV FGFTFQLHLS TRPENYLGEI
     EIWNEAEKQL ESSLNQFGEP WKLNPGDGAF YGPKIDIKIK DAIGRYHQCA TIQLDFQLPI
     RFNLTYVSKD GDDKKRPVII HRAILGSVER MIAILCENYG GKWPFWLSPR QVMVIPVGPS
     CDEYAQQVCK DVFEAGFMAE VDLDHSCTLN KKIRNAQLAQ CNFILVVGEK EKTDSAVNVR
     TRDNKVHGEI LLTSAIEKLK TLKKLRSKNA EEEF
//