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Reviewed, UniProtKB/Swiss-Prot Q0V9S0 (SYTC2_XENTR)

Last modified October 13, 2009. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Probable threonyl-tRNA synthetase 2, cytoplasmic
    EC=6.1.1.3
Alternative name(s):
    Threonine--tRNA ligase
      Short name=ThrRS
    Threonyl-tRNA synthetase-like protein 2
Gene names
Name: tarsl2
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifier8364 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraMesobatrachiaPipoideaPipidaeXenopodinaeXenopusSilurana

Protein attributes

Sequence length814 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Catalytic activity

ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   DomainCoiled coil
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
Gene Ontology (GO)
   Biological processthreonyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

threonine-tRNA ligase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 814814Probable threonyl-tRNA synthetase 2, cytoplasmic
PRO_0000333830

Regions

Coiled coil2 – 7271 Potential

Sequences

Sequence LengthMass (Da)Tools
Q0V9S0-1 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 97A63139DAEE7562

FASTA81493,328
        10         20         30         40         50         60 
MAAHIAQRLT VQEQEIRRLN EEIGRLLELG LQGSVEHSPN PVLEQLRAEN EKLKYRISHL 

        70         80         90        100        110        120 
QRSLREEQER ARPGQYGEPG LKDAAPVEEP KQQNNKAKEK GQATKGENSV GGKPSACEGN 

       130        140        150        160        170        180 
KKNEKKAGKE VDGHKQEGPC APGFIKDRLA LYETLKNEHD ALLAARAAHQ SKPIKITLAD 

       190        200        210        220        230        240 
GKQVDGESWK TTPYQVAIGI SKGLADNVVI AKVNNELWDL DRPLEQDSNV ELLKFDSEEA 

       250        260        270        280        290        300 
QAVYWHSSAH ILGETMENFY GGCLCYGPPI ENGFYYDMYL DGRGVSSNEF PSLENMCKAI 

       310        320        330        340        350        360 
IKEKQPFERL EVSKDLLLEM FKYNKFKCRI LNEKVDTPTT TVYRCGPLID LCRGPHVRHT 

       370        380        390        400        410        420 
GKIKTLKIYK NSSTYWEGRA DMETLQRIYG ISFPDSKLMK EWEQFQEEAK NRDHRKIGRD 

       430        440        450        460        470        480 
QELFFFHDLS PGSCFFLPRG AHIYNTLTDF IKGEYQIRNF TEVASPNIYN SKLWEMSGHW 

       490        500        510        520        530        540 
QHYSENMFSF EVEKETFALK PMNCPGHCLM FGHRPRSWRE LPLRFADFGV LHRNELSGTL 

       550        560        570        580        590        600 
SGLTRVRRFQ QDDAHIFCTM DQIQEEMNGC LQFLQSVYKV FGFTFQLHLS TRPENYLGEI 

       610        620        630        640        650        660 
EIWNEAEKQL ESSLNQFGEP WKLNPGDGAF YGPKIDIKIK DAIGRYHQCA TIQLDFQLPI 

       670        680        690        700        710        720 
RFNLTYVSKD GDDKKRPVII HRAILGSVER MIAILCENYG GKWPFWLSPR QVMVIPVGPS 

       730        740        750        760        770        780 
CDEYAQQVCK DVFEAGFMAE VDLDHSCTLN KKIRNAQLAQ CNFILVVGEK EKTDSAVNVR 

       790        800        810 
TRDNKVHGEI LLTSAIEKLK TLKKLRSKNA EEEF 

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Testis.

Cross-references

Sequence databases

BC121417 mRNA. Translation: AAI21418.1.
RefSeqNP_001096223.1.
UniGeneStr.31543

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ0V9S0.

Genome annotation databases

GeneID100124774.
KEGGxtr:100124774.

Organism-specific databases

XenbaseXB-FEAT-5954361. tarsl2.

Phylogenomic databases

HOVERGENQ0V9S0.

Family and domain databases

InterProIPR002314. aa-tRNA-synt_IIb_cons-reg.
IPR006195. aa-tRNA-synth_II_cons-reg.
IPR004154. Anticodon_bd.
IPR012675. b-grasp_ferredoxin-like.
IPR004095. TGS.
IPR002320. Thr-tRNA-synth_IIa.
IPR018158. Thr-tRNA-synth_IIa_cons-reg.
IPR012947. tRNA_SAD.
[Graphical view]
Gene3DG3DSA:3.40.50.800. Anticodon_bd. 1 hit.
G3DSA:3.10.20.30. Ferredoxin_fold. 1 hit.
PfamPF03129. HGTP_anticodon. 1 hit.
PF02824. TGS. 1 hit.
PF00587. tRNA-synt_2b. 1 hit.
PF07973. tRNA_SAD. 1 hit.
[Graphical view]
PRINTSPR01047. TRNASYNTHTHR.
TIGRFAMsTIGR00418. thrS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYTC2_XENTR
AccessionPrimary (citable) accession number: Q0V9S0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: September 5, 2006
Last modified: October 13, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectXenopus annotation project

Relevant documents

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents