Q0V3D5 (KAD1_PHANO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Adenylate kinase 1
Short name=AK 1
EC=2.7.4.3

Alternative name(s):
ATP-AMP transphosphorylase 1
Adenylate kinase cytosolic and mitochondrial

Gene names

Name:	ADK1
ORF Names:	SNOG_01479

Organism

Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)

Taxonomic identifier

321614 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Dothideomycetes › Pleosporomycetidae › Pleosporales › Pleosporineae › Phaeosphaeriaceae › Phaeosphaeria

Protein attributes

Sequence length	277 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. This small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth. Functions both in cytoplasm and mitochondrion intermembrane space By similarity.
Catalytic activity	ATP + AMP = 2 ADP.
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm › cytosol By similarity. Mitochondrion intermembrane space By similarity.
Sequence similarities	Belongs to the adenylate kinase family. AK2 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm Mitochondrion
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytosol Inferred from electronic annotation. Source: UniProtKB-SubCell mitochondrial intermembrane space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW adenylate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 277	277	Adenylate kinase 1		PRO_0000365682
Regions
	Nucleotide binding	50 – 58	9	ATP By similarity
	Nucleotide binding	73 – 102	30	AMP By similarity
Sites
	Binding site	74	1	AMP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0V3D5 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: F98DEC6A258C5703	FASTA	277	30,155
	10 20 30 40 50 60 MAPTTDPAVN ELKSTVHKLE QRIAELEGRL SGHGGGSSSA QESVRMILMG PPGAGKGTQA 70 80 90 100 110 120 PRIKEKFCAC HLATGDMLRA QVAAKTPLGR EAKKIMDAGG LVSDEIMVNM IKTELENNQE 130 140 150 160 170 180 CAKGFILDGF PRTVTQAEKL DGMLEATQKP LQHAVELQID DQLLVSRITG RLVHPASGRS 190 200 210 220 230 240 YHKIFNPPKA PMTDDATGEP LIQRSDDNEE TLKKRLSTYH AQTSPVVAYY QKTGIWKPVD 250 260 270 ASQDPGQVWK SLLKIFDDKA YVAGRSGSLL NKIGLKN

References

[1]

"Dothideomycete-plant interactions illuminated by genome sequencing and EST analysis of the wheat pathogen Stagonospora nodorum." Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L., Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E., Torriani S.F.F., McDonald B.A., Oliver R.P. Plant Cell 19:3347-3368(2007) [PubMed: 18024570] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SN15 / ATCC MYA-4574 / FGSC 10173.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH445326 Genomic DNA. Translation: EAT91128.1.
RefSeq	XP_001792117.1. XM_001792065.1.
3D structure databases
ProteinModelPortal	Q0V3D5.
SMR	Q0V3D5. Positions 42-253.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SNOT_01479; SNOT_01479; SNOG_01479.
GeneID	5968962.
KEGG	pno:SNOG_01479.
Phylogenomic databases
OMA	SYHKIFN.
OrthoDB	EOG4X0R28.
PhylomeDB	Q0V3D5.
Family and domain databases
InterPro	IPR006259. Adenyl_kin_sub. IPR000850. Adenylate_kin. IPR007862. Adenylate_kinase_lid-dom. [Graphical view]
KO	K00939.
PANTHER	PTHR23359. Adenylate_kin. 1 hit.
Pfam	PF00406. ADK. 1 hit. PF05191. ADK_lid. 1 hit. [Graphical view]
PRINTS	PR00094. ADENYLTKNASE.
TIGRFAMs	TIGR01351. Adk. 1 hit.
PROSITE	PS00113. ADENYLATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KAD1_PHANO

Accession

Primary (citable) accession number: Q0V3D5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	September 5, 2006
Last modified:	November 16, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program